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World’s largest eye imaging and data resource expands across the UK

The world's largest collection of curated eye imaging and linked clinical data is expanding across the country, in an initiative led out of Moorfields Eye Hospital NHS Foundation Trust and UCL (University College London).

5 Nov 2025

USC researchers map genetic architecture of the human corpus callosum

For the first time, a research team led by the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has mapped the genetic architecture of a crucial part of the human brain known as the corpus callosum-the thick band of nerve fibers that connects the brain's left and right hemispheres.

4 Nov 2025

Combined analysis of three blood tests enhances heart attack risk prediction

A combined analysis of blood tests to measure three biomarkers linked to higher risk of cardiovascular disease-lipoprotein a (Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)-may help identify high-risk individuals earlier and guide more personalized prevention strategies, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Massive cross-ancestry study explains why obesity risks differ around the world

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

31 Oct 2025

AI-powered LifeClock forecasts diseases years before symptoms appear

Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.

28 Oct 2025

Electronic health record data reveals trends in cardiovascular diseases before and after COVID-19

The electronic health record data analyzed in this study is anonymized and never leaves a secure data environment, which is only accessible by approved researchers working on approved projects.

28 Oct 2025

New research highlights crucial role of continuous walking patterns for cardiovascular benefit

An international study led by experts at the University of Sydney and the Universidad Europea in Spain has found that longer periods of continuous walking are more beneficial to cardiovascular health than walking the same number of steps in shorter, more sporadic bouts.

28 Oct 2025

Obesity’s health risks shift with age and sex, new genetic study reveals

Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.

27 Oct 2025

What Britain’s post-war sugar rationing teaches us about long-term heart health

A BMJ study found that individuals exposed to sugar rationing during their first 1,000 days of life had significantly lower risks of heart attack, stroke, and heart failure in adulthood. Early-life sugar restriction was linked to a 2.5-year delay in cardiovascular disease onset, suggesting long-term benefits for heart health.

26 Oct 2025

Unlocking the secrets of vascular health through eye imaging

The tiny blood vessels in your eyes might hold the key to predicting a person's risk of developing heart disease and how fast they're biologically aging, according to researchers at McMaster University and Population Health Research Institute (PHRI) - a joint institute of Hamilton Health Sciences and McMaster.

24 Oct 2025

Impaired movement of cerebrospinal fluid predicts dementia risk later in life

Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.

23 Oct 2025

Restricted sugar intake during early life associated with lower cardiovascular risks in adulthood

Restricted sugar intake during early life is linked to lower risks of several heart conditions in adulthood, including heart attack, heart failure, and stroke, finds a study published by The BMJ today using data from the end of UK sugar rationing in 1953.

23 Oct 2025

Night shift work may raise risk of irritable bowel syndrome

The study indicates that night shift work increases irritable bowel syndrome risk, particularly among those with obesity, due to circadian rhythm disturbances.

22 Oct 2025

Strong grip strength lowers risk of organ dysfunction in obesity

People with obesity who also have high muscle mass may be less likely to have obesity-related organ damage.

21 Oct 2025

Predictive factors for physical activity behavior change after cardiovascular diagnosis

Brain connectivity patterns and environmental factors predict which older adults will successfully increase physical activity after receiving a cardiovascular diagnosis.

21 Oct 2025

Genetic inflammatory signature defines depression subtypes and treatment response

Researchers led by Prof. Alessandro Serretti at Kore University of Enna have identified a genetic inflammatory signature that defines specific depression subtypes and influences how patients respond to antidepressant medications, according to new peer-reviewed research published today in Genomic Psychiatry.

21 Oct 2025

Gender-affirming hormone therapy rewrites body proteins to match gender identity

Melbourne researchers have discovered gender-affirming hormone therapy can alter body proteins to match a person's gender identity, potentially affecting susceptibility to certain health conditions.

21 Oct 2025

Simple hand grip test may reveal your future obesity risk

Increased grip strength correlates with lower obesity-related disease risk, suggesting muscle power as a key factor in preclinical obesity management.

20 Oct 2025

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

This Mendelian randomization study found that low-calorie diets may slightly increase the risk of psoriatic arthritis, while vegetarian and gluten-free diets showed no causal links to psoriasis, acne, or atopic dermatitis. The findings challenge assumptions about universally beneficial dietary patterns and highlight the need for cautious interpretation of dietary interventions in inflammatory skin disease.

19 Oct 2025

MRI age clocks reveal how each organ ages differently and predict who develops disease or lives longer

Researchers developed seven MRI-based biological age clocks across major organs using UK Biobank imaging, linking each to proteins, metabolites, genetics, disease risks, mortality, and cognitive decline. These organ-specific age gaps reveal how uneven aging shapes vulnerability to conditions such as diabetes, hypertension, and dementia, opening new paths for precision prevention and clinical trial stratification

19 Oct 2025

UK Biobank News and Research

World’s largest eye imaging and data resource expands across the UK

USC researchers map genetic architecture of the human corpus callosum

Combined analysis of three blood tests enhances heart attack risk prediction

Massive cross-ancestry study explains why obesity risks differ around the world

AI-powered LifeClock forecasts diseases years before symptoms appear

Electronic health record data reveals trends in cardiovascular diseases before and after COVID-19

New research highlights crucial role of continuous walking patterns for cardiovascular benefit

Obesity’s health risks shift with age and sex, new genetic study reveals

What Britain’s post-war sugar rationing teaches us about long-term heart health

Unlocking the secrets of vascular health through eye imaging

Impaired movement of cerebrospinal fluid predicts dementia risk later in life

Restricted sugar intake during early life associated with lower cardiovascular risks in adulthood

Night shift work may raise risk of irritable bowel syndrome

Strong grip strength lowers risk of organ dysfunction in obesity

Predictive factors for physical activity behavior change after cardiovascular diagnosis

Genetic inflammatory signature defines depression subtypes and treatment response

Gender-affirming hormone therapy rewrites body proteins to match gender identity

Simple hand grip test may reveal your future obesity risk

Low-calorie diets linked to higher psoriatic arthritis risk, genetic study suggests

MRI age clocks reveal how each organ ages differently and predict who develops disease or lives longer

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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