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A hybrid approach to re-engineer a SARS-CoV-1 neutralizing antibody against SARS-CoV-2

A hybrid approach involving a combination of conventional discovery and antibody repurposing to combat COVID-19.

21 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors - which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Researchers evaluated distinct immune responses to mRNA and vector-based COVID-19 vaccines and natural SARS-CoV-2 infections.

17 Aug 2023

Long-term use of proton pump inhibitors associated with increased risk of dementia

Researchers determine whether the current and cumulative use of prescription proton pump inhibitors increases the risk of incident dementia.

17 Aug 2023

STING gene variant linked to increased risk of severe group A strep infections

Group A streptococci are fairly common bacteria that can cause, among other things, strep throat or impetigo.

17 Aug 2023

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

New Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.

16 Aug 2023

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Researchers comparatively evaluated humoral immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among infants and their mothers.

16 Aug 2023

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Researchers presented a scalable lipid nanoparticle production (SCALAR) platform to develop SARS-CoV-2 mRNA lipid nanoparticle vaccines.

15 Aug 2023

Study explores the protective effect of transmembrane mucins against SARS-CoV-2 infection

A recent study analyzed the role played by host mucins and mucin glycans with regard to SARS-CoV-2 entry into the airway epithelial cells.

15 Aug 2023

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

New gene therapy shows promise for treating fusion-driven cancers

A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These fusion-driven cancers are caused by an error in cell division that creates a fusion of different genes.

11 Aug 2023

Genetically diverse mice reveal key differences in innate immune responses to SARS-CoV-2

Researchers at The Jackson Laboratory have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection.

11 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

New mechanism discovered for brain repair after ischemic stroke

Patients often experience functional decline after an ischemic stroke, especially due to the brain's resistance to regenerate after damage.

10 Aug 2023

New gene-editing tool helps to study single-base mutations in cancer

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy.

10 Aug 2023

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes.

10 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19.

10 Aug 2023

Duke researchers develop potent antibiotic against drug-resistant superbugs

A scientific journey decades in the making at Duke University has found a new antibiotic strategy to defeat gram-negative bacteria like Salmonella, Pseudomonas and E. coli, the culprits in many urinary tract infections (UTIs).

9 Aug 2023

Enzyme News and Research

A hybrid approach to re-engineer a SARS-CoV-1 neutralizing antibody against SARS-CoV-2

Proxalutamide shows promise as potential COVID-19 treatment

Study suggests antibodies triggered by COVID-19 mRNA vaccination may depend on prior infection history

Long-term use of proton pump inhibitors associated with increased risk of dementia

STING gene variant linked to increased risk of severe group A strep infections

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

Study evaluates differences in humoral immune response against SARS-CoV-2 in infants versus mothers

Researchers develop platform allowing mass-scale production of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Study explores the protective effect of transmembrane mucins against SARS-CoV-2 infection

Study finds way to reverse gene silencing in inner ear cells

Scientists capture first images of ribosome-modifying enzymes in action

New gene therapy shows promise for treating fusion-driven cancers

Genetically diverse mice reveal key differences in innate immune responses to SARS-CoV-2

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

New mechanism discovered for brain repair after ischemic stroke

New gene-editing tool helps to study single-base mutations in cancer

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Duke researchers develop potent antibiotic against drug-resistant superbugs

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Editorial Focus eBook - Proteomics (2nd Edition)

Industry Focus eBook - Life Science Microscopy (2nd Edition)

BFEB: Advances in microplate-based assays and analysis

Biologics stability screening toolkit: Three practical workflows for accelerating formulation development

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy