Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Helix BioPharma awarded U.S. patent for adjunct chemotherapy applications

Helix BioPharma Corp. has announced the issuance of its second DOS47 patent (U.S. Patent # 7,264,800) from the United States Patent & Trademark Office, describing a method and composition for combining targeted DOS47 therapeutics with weakly basic chemotherapeutic drugs in adjunct treatment applications.

18 Sep 2007

Smoking and lactating women - nicotine disrupts infants' sleep patterns

A study from the Monell Chemical Senses Center reports that nicotine in the breast milk of lactating mothers who smoke cigarettes disrupts their infants' sleep patterns.

5 Sep 2007

Blood pressure pill offers diabetics a longer life

A team of Australian researchers say a once-a-day pill to lower blood pressure should be given routinely to people with diabetes to prevent heart disease, strokes and other medical complications.

5 Sep 2007

First finding of a metabolite in 1 sex only

Researchers at the University of Illinois at Chicago have discovered a chemical compound in male blue crabs that is not present in females -- the first time in any species that an entire enzyme system has been found to be activated in only one sex.

24 Aug 2007

Benefits of vitamin D for cancer prevention

A new study looking at the relationship between vitamin D serum levels and the risk of colon and breast cancer across the globe has estimated the number of cases of cancer that could be prevented each year if vitamin D3 levels met the target proposed by researchers.

22 Aug 2007

Sewage reveals community-wide illegal drug use

Public health officials may soon be able to flush out more accurate estimates on illegal drug use in communities across the country thanks to screening test described at the 234 th national meeting of the American Chemical Society, the world's largest scientific society.

22 Aug 2007

Researchers turn mouse into factory for human liver cells

Oregon Health & Science University researchers have figured out how to turn a mouse into a factory for human liver cells that can be used to test how pharmaceuticals are metabolized.

11 Aug 2007

Potential new ways to prevent smoking-related cellular damage

In the current issue of PLoS One, researchers show how a poorly understood and previously unsuspected mechanism may be the key to understanding how life-style associated forms of oxidative stress, such as exposure to cigarette smoke, damage cells in the lungs.

7 Aug 2007

New method for early disease diagnosis

Purdue University researchers worked with the Indiana University School of Medicine to establish a technique that provides a new approach for detecting a number of genetic disorders found in infants and young children.

18 Jul 2007

New genomics-based technology

Bruce S. Gillis, M.D., M.P.H., a medical toxicologist and CEO of the research group, The Cytokine Institute, will present a tutorial on a new genomics-based technology, msds1(TM).

16 Jul 2007

Magnetic resonance spectroscopy for breast cancer

The American Cancer Society recently issued new recommendations for women with a higher risk of developing breast cancer, including those with a family history of breast or ovarian cancer, and those who may carry genetic mutations (BRCA1 or BRCA2) that make them more likely to develop the disease.

11 Jul 2007

Cigarette smoking associated with reduced risk for developing Parkinson's disease

A pooled analysis of data from previous studies suggests that cigarette smoking appears to be associated with a reduced risk for developing Parkinson's disease, with long-term and current smokers at the lowest risk, according to a report in the July issue of Archives of Neurology.

10 Jul 2007

Alternative to blood test to detect drugs in the body

The presence of narcotic substances in a person’s body can usually be detected by a blood or urine test.

23 Jun 2007

Calcium from food best for protecting bone health

Women who get most of their daily calcium from food have healthier bones than women whose calcium comes mainly from supplemental tablets, say researchers at Washington University School of Medicine in St. Louis.

20 Jun 2007

Urocanic acid linked to a deadly parasite of the developing world

Researchers at the University of Pennsylvania have found a link between some of the world's most common parasites that cause infection and disease throughout the developing world and their attraction to a chemical secreted from human and animal skin.

15 Jun 2007

Gamma-secretase acts as a tumor suppressor

Researchers at Burnham Institute for Medical Research (Burnham) have provided the first evidence that gamma-secretase, an enzyme key to the progression of Alzheimer's, acts as a tumor suppressor by altering the pathway of epidermal growth factor receptor (EGFR), a potential treatment target for cancer.

14 Jun 2007

Hot flashes may be a good sign for women with early stage breast cancer

Women on tamoxifen therapy who reported having hot flashes were less likely to develop recurrent breast cancer than those who did not report hot flashes, according to a study from the Moores Cancer Center at the University of California, San Diego (UCSD).

5 Jun 2007

Chemical maps hint at drug's effects on schizophrenia

Antipsychotic drugs do most of their work in the brain, but they also leave behind in the bloodstream a trail of hundreds of chemicals that may be used in the future to direct better treatment for schizophrenia and other psychiatric conditions, say Duke University Medical Center researchers.

16 May 2007

Engineered minichromosomes for medically useful proteins and metabolites

A team of scientists at the University of Missouri-Columbia has discovered a way to create engineered minichromosomes in maize and attach genes to those minichromosomes.

16 May 2007