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Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Peptilogics, a development stage company utilizing its innovative peptide platform to treat multidrug-resistant bacterial infections, today announced it recently held a pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration to discuss the regulatory pathway for the development of PLG0206 for the treatment of prosthetic joint infections.

25 Aug 2018

Scientists design biomaterial that stimulates growth of blood vessels in teeth after root canal

A root canal ranks high on most people's list of dreaded dental procedures. Although the lengthy and sometimes painful surgery relieves the agony of an infection, a root canal results in a dead tooth with no living soft tissue, or dental pulp, inside.

22 Aug 2018

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

Remember the scene in the movie Mission: Impossible when Tom Cruise has to sneak into the vault? He had to do all sorts of moves to avoid detection. That's what it's like to sneak a targeted drug into a kidney and keep it from getting eliminated from the body.

22 Aug 2018

Scientists discover peptides that can be used as new antibiotic candidates

The human body produces many antimicrobial peptides that help the immune system fend off infection. Scientists hoping to harness these peptides as potential antibiotics have now discovered that other peptides in the human body can also have potent antimicrobial effects, expanding the pool of new antibiotic candidates.

21 Aug 2018

New tool fills gap in Small Molecules market

This news story covers the launch of SmallMolecules.com, an online tool for scientists looking to buy and compare molecules for their experiments.

From SmallMolecules.com 17 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

Finding the light in antimicrobials

Hundreds of polymers which kill drug-resistant superbugs in novel ways could be produced and tested using light, using this new method.

14 Aug 2018

Simple score helps predict which hospitalized heart attack patients are at high risk of readmissions

Tracking just seven factors of heart attack patients when they are first admitted to the hospital can help flag those most at risk for 30-day readmission, researchers from UT Southwestern found.

13 Aug 2018

Discovery could lead to new drugs against infection and inflammation

Researchers at Lund University in Sweden, have in collaboration with colleagues in Copenhagen and Singapore, mapped how the body's own peptides act to reduce infection and inflammation by deactivating the toxic substances formed in the process.

13 Aug 2018

MSU researchers uncover the effects of aging on regenerative ability of kidneys

Autophagy is a process of destruction and processing of damaged cell components by the cells themselves. It is used by a cell to clean itself of excessive organelles and sometimes for self-execution. This adaptive mechanism supports a healthy phenotype on the cellular level.

13 Aug 2018

Collaboration between Merck and InnoCore could improve biologic drug delivery

Following today’s (Friday 3 August) announcement of Merck and InnoCore’s collaboration, Rahael Maladwala, Pharma Analyst at GlobalData, a leading data and analytics company, offers his view on what this might mean for biologic drug delivery:

10 Aug 2018

Researchers describe new class of potent inhibitors against amyloid plaques

Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available.

9 Aug 2018

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

A new study in the American Journal of Pathology reports for the first time that injection of neuropeptide vasoactive intestinal peptide directly into the eye of mice enhanced corneal graft survival.

7 Aug 2018

Scientists develop novel peptide drug that could potentially stop development of liver cancer

A research team led by scientists from the Cancer Institute of Singapore at the National University of Singapore has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma or primary liver cancer.

2 Aug 2018

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue transmission often precedes Zika virus infection, suggesting that women who previously acquired dengue immunity may be bitten by ZIKV-carrying mosquitoes during pregnancy.

2 Aug 2018

Peptides News and Research

Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Scientists design biomaterial that stimulates growth of blood vessels in teeth after root canal

Researchers engineer peptide nanoparticles to outsmart biological system and target kidney cells

Scientists discover peptides that can be used as new antibiotic candidates

New tool fills gap in Small Molecules market

Discovery may help broaden the scope of defenses against HPV

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Finding the light in antimicrobials

Simple score helps predict which hospitalized heart attack patients are at high risk of readmissions

Discovery could lead to new drugs against infection and inflammation

MSU researchers uncover the effects of aging on regenerative ability of kidneys

Collaboration between Merck and InnoCore could improve biologic drug delivery

Researchers describe new class of potent inhibitors against amyloid plaques

Injecting vasoactive intestinal peptide into the eye enhances corneal graft survival

Scientists develop novel peptide drug that could potentially stop development of liver cancer

Mice study shows mother's dengue immunity protects unborn from ZIKA infection

Progesterone and lipoic acid combination ameliorates death of photoreceptors in the retina

New drug offers hope to prevent attacks of hereditary angioedema

Researchers design and create new molecule that can kill malarial parasites

New target for pneumonia seems to restore tight barriers and fluid clearance in the lungs

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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