Immune System News and Research

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Two studies discover new enzyme that acts as a sensor of innate immunity

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic infections.

16 Feb 2013

Spherical nucleic acids could revolutionize biomedicine

Northwestern University's Chad A. Mirkin, a world-renowned leader in nanotechnology research and its application, has invented and developed a powerful material that could revolutionize biomedicine: spherical nucleic acids (SNAs).

16 Feb 2013

Patients with untreated depression are poorly protected by shingles vaccination

Results from a new study published in Clinical Infectious Diseases suggest a link between untreated depression in older adults and decreased effectiveness of the herpes zoster, or shingles, vaccine.

16 Feb 2013

IKBKE gene plays a key role in tobacco-induced lung cancer

Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response.

16 Feb 2013

Natural probiotic supplement can help male mice produce healthier bones

In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.

16 Feb 2013

Depression reduces efficacy of shingles vaccine

Research suggests that the varicella zoster, or shingles, vaccine is less effective in older people with untreated depression.

15 Feb 2013

Study discovers new predictor for suicidal thinking

When people lose hope that they will ever get another good night's sleep, they become at high risk for suicide, researchers report.

15 Feb 2013

New insights into how cells stick to each other and to other bodily structures

Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function in the formation of tissue structures and organs. It's thought that abnormalities in their ability to do so play an important role in a broad range of disorders, including cardiovascular disease and cancer.

15 Feb 2013

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that helps protect a cell's genes against these DNA interlopers.

15 Feb 2013

Study reveals how calcium signal repairs damaged tissue

For the first time scientists studying the cellular processes underlying the body's response to healing have revealed how a flash of calcium is the very first step in repairing damaged tissue. The findings, published in Current Biology, could lead to new therapies that speed up the healing process following injury or surgery.

15 Feb 2013

Researchers show how gene mutations shift and evolve over time in chronic lymphocytic leukemia

Tumors are not factories for the mass production of identical cancer cells, but are, in reality, patchworks of cells with different patterns of gene mutations. In a new study, researchers at Dana-Farber Cancer Institute and the Broad Institute show, more fully than ever before, how these mutations shift and evolve over time in chronic lymphocytic leukemia (CLL) - providing a strobe-like look at the genetic past, present, and future of CLL tumors.

15 Feb 2013

Third Rock Ventures announces formation of Jounce Therapeutics

Third Rock Ventures, LLC today announced the formation of Jounce Therapeutics, Inc. with a $47 million Series A financing of the company. Jounce is focused on the discovery and development of first-in-class cancer immunotherapies designed to harness the patient's immune system to seek out and attack cancerous cells and tumors.

15 Feb 2013

Benaroya Research Institute establishes T1D Exchange Biobank Operations Center

In a major effort to advance discoveries in type 1 diabetes research, the Benaroya Research Institute at Virginia Mason (BRI) established the T1D Exchange Biobank Operations Center with a $4.4 million grant from The Leona M. and Harry B. Helmsley Charitable Trust.

15 Feb 2013

Gamida Cell announces results from NiCord Phase I/II study on hematological malignancies

Gamida Cell announced today the successful results of the Phase I/II study of its second pipeline product NiCord, umbilical cord derived stem cells expanded using the company's proprietary NAM technology.

15 Feb 2013

Allografts better survive implantation into brains of immunocompetent research mice

Researchers at the Johns Hopkins University in Baltimore, Md., and the Mossakowski Medical Research Centre in Warsaw, Poland, have found that nonself-donated cells (allografts) better survive implantation into the brains of immunocompetent research mice when the grafts are injected into the striatum (STR) of the brain rather than injected into the forceps minor (FM) region.

14 Feb 2013

Combination of Methotrexat and Tofacitinib shows promise against rheumatoid arthritis

Together with colleagues from the international rheumatic diseases research community, scientists of the Charité - Universitätsmedizin Berlin have presented a new therapy approach for the treatment of rheumatoid arthritis (RA), a chronic form of joint inflammation.

14 Feb 2013

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

"Good" bacteria that live in our intestines have been linked with a variety of health benefits, from fighting disease to preventing obesity. In a new study, Kriston Ganguli of Massachusetts General Hospital for Children and Harvard Medical School and her colleagues have discovered another advantage to these friendly microscopic tenants: Chemicals secreted by good bacteria that typically live in the intestines of babies could reduce the frequency and severity of a common and often-lethal disease of premature infants.

14 Feb 2013

Immune System News and Research

Two studies discover new enzyme that acts as a sensor of innate immunity

Spherical nucleic acids could revolutionize biomedicine

Patients with untreated depression are poorly protected by shingles vaccination

IKBKE gene plays a key role in tobacco-induced lung cancer

Natural probiotic supplement can help male mice produce healthier bones

Depression reduces efficacy of shingles vaccine

Study discovers new predictor for suicidal thinking

New insights into how cells stick to each other and to other bodily structures

Researchers discover SCANR that helps protect a cell's genes against DNA interlopers

Study reveals how calcium signal repairs damaged tissue

Researchers show how gene mutations shift and evolve over time in chronic lymphocytic leukemia

Third Rock Ventures announces formation of Jounce Therapeutics

Benaroya Research Institute establishes T1D Exchange Biobank Operations Center

Gamida Cell announces results from NiCord Phase I/II study on hematological malignancies

Allografts better survive implantation into brains of immunocompetent research mice

Combination of Methotrexat and Tofacitinib shows promise against rheumatoid arthritis

Probiotics shows promise in reducing both incidence and severity of necrotizing enterocolitis

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Researchers investigate new avenue of treatment to help boost poor pancreatic cancer survival rates

Bedside baths and bloodstream infections in children: an interview with Aaron Milstone

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