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AI and real-world data can advance patient care in academic health systems

Academic medical centers could transform patient care by adopting principles from learning health systems principles, according to researchers from Weill Cornell Medicine and the University of California, San Diego.

27 Jun 2025

Exploring neural responses to mental exhaustion in healthy adults

In experiments with healthy volunteers undergoing functional MRI imaging, scientists have found increased activity in two areas of the brain that work together to react to, and possibly regulate, the brain when it's "feeling" tired and either quits or continues exerting mental effort.

27 Jun 2025

Brain activity reveals lingering sensitivity to negative cues after depression recovery

Researchers have found that even after recovery, individuals who previously experienced depression may retain a heightened sensitivity to negative cues and face challenges in regulating responses to potential punishment.

27 Jun 2025

New brain imaging benchmark may improve Alzheimer's detection in diverse populations

A team of researchers from the Keck School of Medicine of USC's Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has identified a new brain imaging benchmark that may improve how researchers classify biologically meaningful changes associated with Alzheimer's disease, especially in Hispanic and non-Hispanic white populations.

26 Jun 2025

Can your athletic past raise your risk for atrial fibrillation?

Elite retired rowers face a nearly threefold increased risk of atrial fibrillation compared to the general population, driven by a combination of long-term cardiac remodelling and underlying polygenic genetic susceptibility.

26 Jun 2025

Study finds overlap between chemotherapy side effects and brain aging

While chemotherapy can be lifesaving, it also damages DNA and leads to cognitive issues known as "chemo brain." These effects resemble the memory and learning problems seen in older adults, prompting University of Oklahoma researchers to investigate this unique overlap of cognitive decline.

26 Jun 2025

Unknown organelle discovery could open the door to new treatments for inherited diseases

The discovery of an unknown organelle inside our cells could open the door to new treatments for devastating inherited diseases.

26 Jun 2025

More people survive heart attacks but face ongoing cardiac risks

In 1970, someone over the age of 65 hospitalized for a heart attack in the United States had about a 60% chance of leaving the hospital alive. Today, the survival rate is over 90%, with even better outcomes for younger patients.

26 Jun 2025

Tirzepatide rewires appetite and slashes calorie intake in new obesity trial

A 6-week randomized trial found that tirzepatide significantly reduced energy intake, appetite, and cravings in adults with overweight or obesity, outperforming liraglutide and placebo. Brain imaging revealed that tirzepatide also lowered neural responses to high-fat, high-sugar food cues, offering mechanistic insight into its potent weight-loss effects.

25 Jun 2025

$Men face silent threat of weak bones and fractures$

Men face silent threat of weak bones and fractures

Weak bones can have deadly consequences. Women often get bone density tests to screen for osteoporosis, yet many men don't even realize they are at risk until they suffer a major fracture.

25 Jun 2025

Integrating multiple MRI modalities improves cognitive ability prediction

Predicting cognitive abilities from brain imaging has long been a central goal in cognitive neuroscience.

25 Jun 2025

Study uncovers how the brain amplifies pain from multiple sources

When pain strikes from multiple sources-such as a paper cut followed by contact with hot water-the experience can feel disproportionately intense. But is this agony merely additive, or does the brain integrate these signals in a way that amplifies suffering?

25 Jun 2025

Pathpresenter receives FDA 510(K) clearance for digital pathology clinical viewer

PathPresenter, a leading Image Management System and workflow platform for digital pathology, has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the PathPresenter Clinical Viewer for the purpose of primary diagnosis.

25 Jun 2025

Flexible wireless implant offers hope for chronic pain sufferers

Chronic pain is a debilitating condition that severely impacts quality of life, often leading to reliance on opioid medications with their severe side effects and addiction risks.

24 Jun 2025

Unhealthy teen diets reshape the brain and drive lifelong eating habits, study finds

Adolescent diets high in fat and sugar disrupt the development of the prefrontal cortex and hippocampus, impacting cognition, memory, and impulse control. These brain changes can promote unhealthy eating behaviors and obesity risk that persist into adulthood.

24 Jun 2025

Mayo Clinic researchers discover how ovarian cancer may begin

Little is known about what causes ovarian cancer, and there is no way to detect it early yet. About 75% of the time when someone is diagnosed with ovarian cancer, it has already progressed to stage 3 or stage 4, which means it has spread to other parts of the body.

24 Jun 2025

New PET/CT imaging technique enables early detection of multiple forms of cardiomyopathy

A new PET/CT imaging technique that visualizes activated fibroblasts in the heart muscle enables early detection of multiple forms of cardiomyopathy, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

New PET radiotracer offers clearer view of brain inflammation

A newly developed PET radiotracer has shown the ability to produce high-quality images of real-time brain inflammation, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2025 Annual Meeting.

24 Jun 2025

New AI-based brain mapping tool receives FDA clearance for use in neurosurgery

A new AI-based technology that rapidly maps the brain to locate sensitive areas that control speech, vision, movement and other critical functions has received authorization from the Food and Drug Administration (FDA), enabling it to be marketed to hospitals with the aim of enhancing the precision of neurosurgeries.

23 Jun 2025

New molecular imaging agent shows high accuracy in detecting liver cancer

A novel molecular imaging agent targeting glypican-3 (GPC3) has demonstrated high sensitivity and specificity in detecting hepatocellular carcinoma (HCC), including tumors smaller than one centimeter, according to results from a pilot clinical study.

23 Jun 2025