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AI tool speeds up patient screening for heart failure trials

Artificial intelligence (AI) can rapidly screen patients for clinical trial enrollment, according to a new study published in JAMA and led by Mass General Brigham researchers.

17 Feb 2025

Groundbreaking ALS platform trial accelerates research and drug testing

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with few treatment options. Since 2018, the Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, has been working with national and international stakeholders to accelerate ALS research by launching the first platform trial in ALS to simultaneously test multiple drugs using shared trial infrastructure and placebo data.

17 Feb 2025

Study links sucrase defects to increased IBS risk and severe symptoms

Sucrase-isomaltase (SI) is an intestinal enzyme critical for the digestion of dietary carbohydrates, particularly sucrose and starch.

17 Feb 2025

Study sheds new light on brain evolution

In a new study published in Science, a Belgian research team explores how genetic switches controlling gene activity define brain cell types across species.

17 Feb 2025

Icaritin softgel capsules offer new hope for hepatocellular carcinoma patients

Announcing a new publication for Acta Materia Medica journal. Icaritin (ICA) is a prenylflavonoid natural product extracted from plants of the Epimedium genus.

17 Feb 2025

Poll reveals parents' views on teens getting cosmetic treatments

For teens who may be self-conscious about issues such as acne scarring or discolored teeth, non-surgical cosmetic procedures are an increasingly popular way to address their concerns.

17 Feb 2025

New AI hub for healthcare and neuromodulation set to launch in Geneva

The University hospitals of Geneva (HUG), the Department of Health and Mobilities (DSM) of the Canton of Geneva and the Wyss Center for Bio and Neuro Engineering enter into a three-party agreement to create an artificial intelligence (AI) reference hub for healthcare and neuromodulation with its inauguration set for the second half of the year.

17 Feb 2025

MARBLE algorithm decodes brain activity to identify universal mental patterns

In the parable of the blind men and the elephant, several blind men each describe a different part of an elephant they are touching – a sharp tusk, a flexible trunk, or a broad leg – and disagree about the animal's true nature.

17 Feb 2025

Innovative photodynamic therapy targets melanoma with light-activated dyes

Melanoma is one of the most aggressive skin cancers, with over 300,000 new cases reported worldwide each year. In Europe, the number of diagnoses has been rising rapidly.

17 Feb 2025

Study shows how pituitary macrophages impact hormone regulation

Finnish researchers show in a new study that pituitary macrophages, the immune cells located in the pituitary gland, help regulate hormonal balance. It is possible that in the future, macrophage cells could be used to treat endocrine disorders that can lead, for example, to infertility.

17 Feb 2025

Breakthrough computational tool enhances design of targeted antiviral therapies

Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication.

17 Feb 2025

Researchers develop a way to treat muscular atrophy using regenerative medicine

Researchers from Tokyo Metropolitan University have developed a way to treat ageing-related muscular atrophy using regenerative medicine.

17 Feb 2025

Sweet taste receptors found in the heart could affect heartbeat

In a surprising discovery, scientists have found that the heart possesses "sweet taste" receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can modulate the heartbeat.

17 Feb 2025

Stanford researchers identify key variants linked to inherited cancer risk

Thousands of single changes in the nucleotides that make up the human genome have been associated with an increased risk of developing cancer.

17 Feb 2025

Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

ICHOM develops standard dataset that defines heart valve disease outcomes

The International Consortium for Health Outcomes Measurement (ICHOM) has developed a globally inclusive standard dataset of 16 patient-centered outcome measures for people with heart valve disease, regardless of treatment (surgical or transcatheter procedure), according to a new report published today in the American Heart Association's journal Circulation: Cardiovascular Quality & Outcomes.

17 Feb 2025