Immune System News and Research

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New gut-on-chip model could revolutionize immunotherapy for melanoma

A team of researchers from the European Institute of Oncology and the Politecnico di Milano, coordinated by Luigi Nezi, Team Leader of the Department of Experimental Oncology, European Institute of Oncology, and Marco Rasponi, Full Professor of the Department of Electronics, Informatics and Bioengineering, Politecnico di Milano, have developed a "gut-on-chip" (a miniature model of the human intestine on a chip-sized device) capable of reproducing the main features of intestinal inflammation and of predicting the response of melanoma patients to immunotherapy treatment.

14 Feb 2025

Researchers uncover cause of persistent blood clots despite treatment

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

14 Feb 2025

How immune cells and neurons secretly shape brain health, behavior, and disease

Scientists explore how the immune and nervous systems constantly communicate, influencing brain diseases, behavior, and repair while shaping responses to environmental factors like sleep, diet, and pollution.

13 Feb 2025

Enzyme found in lymphatic cells enhances immune activity against tumors

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges.

13 Feb 2025

Testosterone treatment can save lives for men with Klinefelter syndrome

Testosterone treatment significantly reduces mortality among men with Klinefelter syndrome. Researcher calls for changes in guidelines to ensure more patients receive the necessary treatment.

13 Feb 2025

Immunotherapy reduces sunspots and skin cancer by 65%

University of Queensland researchers have discovered immunotherapy, when used to treat people with advanced cancers, also helps reduce sunspots and skin cancers by at least 65 per cent.

12 Feb 2025

Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.

12 Feb 2025

New insights could help prevent peripheral neuropathy or slow disease onset

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes.

12 Feb 2025

Diabetes plays key role in the emergence and expansion of antibiotic resistance

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to evolve and spread.

12 Feb 2025

New dual-target therapy offers hope for better breast cancer treatment

Researchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), in collaboration with Pfizer, have discovered new insights into possible future treatments for breast cancer.

12 Feb 2025

New discovery could overcome immune therapy failure in ovarian cancer

University of Virginia Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment.

12 Feb 2025

New technique sheds light on how Tregs control the immune system

Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for scientists.

12 Feb 2025

Osaka University researchers develop innovative tool to study immune regulation

Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for scientists. T cells, which are the frontline warriors in the battle against the infections, have been a major focus of research.

12 Feb 2025

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025

Study explores why newborns regenerate heart tissue better than adults

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults aren't so lucky.

11 Feb 2025

Many Americans take supplements for immune support, but doctor recommendations are low

Study finds 11% of U.S. adults used dietary supplements for immune support pre-pandemic, emphasizing the importance of healthcare professional recommendations.

11 Feb 2025

New mechanism of immune evasion discovered in cancer cells

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

11 Feb 2025

EBV exposure linked to life-threatening cancer risk in kidney transplant patients

More than 90% of the adult population in the U.S. is or has been infected with Epstein Barr virus (EBV). EBV is a highly contagious member of the herpes virus family, best known for causing infectious mononucleosis ("mono") and for its association with several cancers and autoimmune diseases.

10 Feb 2025

Understanding the process and risks of tattoo removal

Sometimes people get a permanent tattoo then later decide they no longer want it. Life situations change or maybe the tattoo just didn't come out as hoped.

10 Feb 2025

GUK1 enzyme plays crucial role in lung cancer metabolism and growth

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, and it can shapeshift in unpredictable ways to evade treatment.

10 Feb 2025