Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

Researchers explore the therapeutic potential of circadian-modulating interventions to treat Alzheimer’s disease.

27 Aug 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

Competency-based cardiac imaging delivery is needed for effective and efficient patient care, according to a European Society of Cardiology (ESC) statement published today in European Heart Journal, a journal of the ESC.

25 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

A stem cell patch developed by USC researchers for patients with macular degeneration will soon be tested in a phase 2b clinical trial.

24 Aug 2023

Study finds examining retinal structure could provide markers for Parkinson disease

A new paper examined the retinal data from Parkinson disease patients in attempt to identify disease markers.

24 Aug 2023

What are the needs for clinical application of next-generation sequencing for microbiological diagnosis?

Scientists have surveyed to understand the need for clinical application of next-generation sequencing in microbiology laboratories.

23 Aug 2023

Time-restricted feeding may correct the circadian disruptions in Alzheimer's disease

One of the hallmarks of Alzheimer's disease is disruption to the body's circadian rhythm, the internal biological clock that regulates many of our physiological processes.

21 Aug 2023

Sleep dysfunction is underreported and underrecognized in Huntington's disease

A good night's sleep is essential for everyone. In individuals with Huntington’s disease (HD), sleep disturbances constitute an additional burden that may exacerbate disease outcomes and impact patients’ quality of life.

21 Aug 2023

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

Is there an association between sleep-disordered breathing and Alzheimer's disease?

Researchers evaluated the impact of sleep-disordered breathing (SDB) on neuroimaging biomarkers of Alzheimer's disease (AD).

21 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

Japanese squirrels may be a model for human amyloidosis

A research group led by Dr. Tomoaki Murakami from the Tokyo University of Agriculture and Technology has revealed that fibrinogen Aα-chain amyloidosis, a previously unreported disease in animals other than humans, is highly prevalent in Japanese squirrels (Sciurus lis).

18 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors - which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Can your screen time affect your bowel movements?

The causal relationship between leisure screen time and irritable bowel syndrome.

18 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors

A new research paper was published by Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) in Volume 15, Issue 15, entitled, "Associations between klotho and telomere biology in high stress caregivers."

17 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023

Pathology News and Research

Further Reading

Study discovers method to classify febrile illness with a single blood sample

A review of the neurological imaging techniques in dementia diagnosis

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

New research sheds light on role of KRAS mutations in pancreatic cancer

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

Study finds examining retinal structure could provide markers for Parkinson disease

What are the needs for clinical application of next-generation sequencing for microbiological diagnosis?

Time-restricted feeding may correct the circadian disruptions in Alzheimer's disease

Sleep dysfunction is underreported and underrecognized in Huntington's disease

New microneedles could monitor melanoma therapy response

Is there an association between sleep-disordered breathing and Alzheimer's disease?

Severe COVID-19 causes long-lasting changes to immune system stem cells

Japanese squirrels may be a model for human amyloidosis

Proxalutamide shows promise as potential COVID-19 treatment

Can your screen time affect your bowel movements?

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

Klotho levels and telomere length may be associated through a coordinated downregulation of longevity factors

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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