Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

3DHISTECH and Epredia open pathology innovation incubator to accelerate advancements in cancer diagnostics

Two leading pathology and diagnostics companies, 3DHISTECH of Hungary and Epredia, a member of PHC Group (headquartered in Japan), announce the opening of the Pathology Innovation Incubator in Budapest to develop methods and equipment for faster and more precise diagnosis of cancer and tumor lesions.

From 3DHISTECH Ltd. 25 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Everyday chemicals linked to increased cancer risk, especially in women

This study identifies links between exposure to chemicals like PFAS, parabens, and phenols and increased cancer risk, particularly among women and across racial groups. The findings spotlight the role of environmental toxins in hormone-related cancers, suggesting new avenues for cancer prevention and mitigation strategies.

24 Sep 2023

New insights into the molecular mechanism of protein degradation

Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease.

22 Sep 2023

New science committee to support One Medicine research at Humanimal Trust

Humanimal Trust, the charity founded in 2014 by orthopaedic veterinary surgeon, Professor Noel Fitzpatrick, has announced a new Committee of independent advisors, made up of leading human and animal health professionals, academics and researchers from around the world.

22 Sep 2023

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.

22 Sep 2023

Placental disease: A key contributor to unexplained pregnancy loss

New study in Reproductive Sciences identifies placental diseases as the likely cause for 99% of unexplained pregnancy losses, shedding light on miscarriages and stillbirths. The research suggests that identifying specific placental pathologies could lead to more preventative measures.

21 Sep 2023

Study sheds light on the cause of craniosynostosis in infants

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led by researchers at Weill Cornell Medicine.

21 Sep 2023

Brain activity changes predict recovery from early PTSD symptoms

After a traumatic experience, most people recover without incident, but some people - between 2% and 10%- develop posttraumatic stress disorder (PTSD), a mental health condition that can cause debilitating symptoms of anxiety due to emotional dysregulation.

21 Sep 2023

Lurie Children's neurosurgeon performs computer-guided radiofrequency ablation to decrease hypertonia in cerebral palsy

Jeffrey Raskin, MS, MD, a neurosurgeon at Ann & Robert H. Lurie Children's Hospital of Chicago, performed the first ever computer-guided radiofrequency ablation to decrease excessive muscle tone (called hypertonia) in a child with cerebral palsy.

20 Sep 2023

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Hyperdiploidy is a genetic condition observed in cancer cells, where the cells contain more chromosomes than usual.

20 Sep 2023

Early treatment with convalescent plasma may reduce risk of long COVID

Findings from a nationwide, multicenter study led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health suggest that patients with COVID-19 have less chance of developing post-COVID conditions - commonly known as long COVID - if they receive early treatment with plasma from convalescent (recovered) COVID patients that contain antibodies against SARS-CoV-2, the virus that causes COVID-19.

20 Sep 2023

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

20 Sep 2023

Researchers identify key mechanisms to address future treatments for hereditary blindness

There are still many enigmas about the mechanism of action of the CERKL gene, which causes retinitis pigmentosa and other hereditary vision diseases.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

The National Institutes of Health/National Institute on Aging recently awarded a $13.7 million grant to a project led by Boston University Chobanian & Avedisian School of Medicine principal investigators Lindsay Farrer, PhD, chief of biomedical genetics and distinguished professor of genetics, and Richard Sherva, PhD, assistant professor of medicine in biomedical genetics, for research using whole genome sequencing and other approaches to identify genetic factors for Alzheimer disease (AD) in Jews currently living in Israel who trace their ancestors to southern Spain and locations in the Middle East and North Africa (MENA) and Arab citizens of Israel.

15 Sep 2023

How does the APOE4 gene play both hero and villain in your health risks?

The study reveals that APOE4, a genetic risk factor for Alzheimer's Disease and cardiovascular diseases, has complex effects on mortality risk. While APOE4 carriers with higher AD neuropathology have increased mortality risk, those with low neuropathology had a reduced risk of certain cancers, warranting further research into this genetic factor's diverse impact on health outcomes.

14 Sep 2023

Innovative technique provides unparalleled insight into autism pathology

Does the human brain have an Achilles heel that ultimately leads to Autism? With a revolutionizing novel system that combines brain organoid technology and intricate genetics, researchers can now comprehensively test the effect of multiple mutations in parallel and at a single-cell level within human brain organoids.

13 Sep 2023

Study helps explain why solid tumors often spread to the spine

The vertebral bones that form the spine are derived from a distinct type of stem cell that secretes a protein favoring tumor metastases, according to a study led by researchers at Weill Cornell Medicine.

13 Sep 2023

Researchers develop new protocol to study white matter injury in Alzheimer's disease

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 16, entitled, "Microvascular contributions to white matter injury in Alzheimer's disease."

13 Sep 2023

Pathology News and Research

Further Reading

3DHISTECH and Epredia open pathology innovation incubator to accelerate advancements in cancer diagnostics

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Everyday chemicals linked to increased cancer risk, especially in women

New insights into the molecular mechanism of protein degradation

New science committee to support One Medicine research at Humanimal Trust

Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Placental disease: A key contributor to unexplained pregnancy loss

Study sheds light on the cause of craniosynostosis in infants

Brain activity changes predict recovery from early PTSD symptoms

Lurie Children's neurosurgeon performs computer-guided radiofrequency ablation to decrease hypertonia in cerebral palsy

St. Jude Children's researchers better define hyperdiploidy in childhood B-ALL

Early treatment with convalescent plasma may reduce risk of long COVID

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

Researchers identify key mechanisms to address future treatments for hereditary blindness

Single-cell screening of cerebral organoids to identify developmental defects in autism

BU researchers receive NIH grant to identify genetic factors for Alzheimer's disease

How does the APOE4 gene play both hero and villain in your health risks?

Innovative technique provides unparalleled insight into autism pathology

Study helps explain why solid tumors often spread to the spine

Researchers develop new protocol to study white matter injury in Alzheimer's disease

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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