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Study defines new starting points for therapy and vaccine research on coronavirus

The SARS coronavirus 2 (SARS-CoV-2) infects lung cells and is responsible for the COVID-19 pandemic. The viral spike protein mediates entry of the virus into host cells and harbors an unusual activation sequence.

4 May 2020

Study reveals variable sites in novel coronavirus SARS-CoV-2

Understanding the varying aggressiveness of SARS-CoV-2 may provide valuable data to trace its spread across populations. In the study, published on the preprint server BioRxiv, the researchers traced amino acid variants that possess high frequency in Europe, particularly in Italy, one of the hardest-hit countries.

4 May 2020

Scientists develop CRISPR-based test for SARS-CoV-2

Now, a team of scientists at the University of California Santa Barbara has developed a low-cost, rapid, and high-tech test that can detect SARS-CoV-2 effectively. They have developed a CRISPR-based test that is sensitive and effective as traditional tests.

4 May 2020

Researchers discover hidden symmetry in chemical kinetic equations

Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.

4 May 2020

Scientists develop new way to deliver molecules that target specific genes within cells

A group of researchers from University of Toronto Engineering and SickKids Hospital have developed a new way to deliver molecules that target specific genes within cells.

4 May 2020

SARS-CoV-2 receptor ‘mimic' could prevent COVID-19

Researchers from Italy have developed an exciting new peptide drug that could potentially prevent the coronavirus from infecting people’s cells. The paper, published on the preprint server bioRxiv* in April 2020, describes a small molecule that can bind to and block the attachment site on the virus spike protein, preventing its entry into the host cell.

4 May 2020

Research detects a more dangerous SARS-CoV-2 mutation

A new study published on the preprint server bioRxiv in May 2020 reports the setting up of a system to help track new mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is behind the current COVID-19 pandemic. This will help analyze mutations to find and track the spread of those that are most likely to increase the pathogenicity of the virus, either by making it easier to transmit or by enhancing its resistance to treatment.

4 May 2020

Study: Chronic exposure to inhaled nicotine alone leads to pulmonary hypertension

A study conducted by a team of researchers at LSU Health New Orleans has shown for the first time that chronic exposure to inhaled nicotine alone increases blood pressure (hypertension), in both the body's general circulation and in the lungs that can lead to pulmonary hypertension.

4 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

Study reveals antiviral properties of glycosaminoglycans against SARS-CoV-2

Glycosaminoglycans can inhibit cell invasion by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses, which supports the utilization of such therapeutics in the fight against coronavirus disease (COVID-19) – reports a new study available on the preprint server bioRxiv.

3 May 2020

Low molecular weight heparins inhibit SARS-CoV-2 cell invasion

A recent paper available on the preprint server bioRxiv* reports preliminary data on the ability of low molecular weight heparins to interact with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), elicit structural changes in its key proteins and subsequently halt cell invasion.

3 May 2020

Inventor of hepatitis C cure wins prestigious award from University of Edinburgh

A medicinal chemist who found a cure for the viral disease hepatitis C has received a prestigious award from the University of Edinburgh.

3 May 2020

Discovery heralds a new strategy in the hunt for antibiotics

Scientists have identified a key process in the way bacteria protect themselves from attack - and it heralds a new strategy in the hunt for antibiotics.

3 May 2020

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

DNA damage in general and DNA strand breaks in particular occur every day in all cells of the human body.

3 May 2020

High blood pressure drugs found to be safe for COVID-19 patients

Despite concerns expressed by some experts, common high blood pressure drugs did not increase the risk of contracting COVID-19 - or of developing severe disease - in a study of 12,594 patients.

3 May 2020

Research reveals mechanism underlying Parkinson's dyskinesia

Many people with Parkinson's disease eventually develop debilitating movements called dyskinesia, a side effect of their much-needed dopamine replacement medication.

3 May 2020

Study finds potential new therapeutic targets for childhood brain tumors

People with the genetic condition neurofibromatosis type 1 (NF1) are prone to developing tumors on nervous system tissue.

2 May 2020

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

In this interview, Dr. Polinski and Dr. Atabakhsh discuss the importance of developing biomarkers for Parkinson’s and the partnership between MJFF and Abcam.

From Abcam 1 May 2020