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UCLA study reveals key role of mismatch repair genes in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

11 Feb 2025

New guidelines urge caution with ketamine use for mental health treatment

The anesthetic ketamine is being hailed as a breakthrough therapy for people with post-traumatic stress disorder (PTSD), treatment-resistant depression and other mood disorders.

11 Feb 2025

Scientists discover functional role of introns in cells

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress.

11 Feb 2025

Older adults experience greater happiness and purpose after Covid-19

Older people have greater general happiness, life satisfaction and sense of purpose than they did before the Covid-19 pandemic.

11 Feb 2025

New project aims to measure nicotine use through sewage

University of California, Merced's Nicotine and Cannabis Policy Center has embarked on an innovative partnership with researchers at the university who track an entire community's health and habits with samples of human sewage.

11 Feb 2025

Global study reveals diversity in healthy vaginal microbiomes

Seeking to understand what constitutes a healthy vaginal microbiome, a global research collaboration that includes a Rutgers-New Brunswick scientist has reported a series of findings, including identifying which bacteria thwart vaginal disease and determining that microbiomes vary significantly across human populations.

11 Feb 2025

Nanoscale plastic particles enhance toxin uptake in plants and human cells

Micro- and nanoscale plastic particles in soil and water can significantly increase how much toxic chemicals plants and human intestinal cells absorb, according to two new studies from Rutgers Health that raise fresh concerns about food safety from plastic pollution.

11 Feb 2025

Short-course, higher dose vaginal brachytherapy for endometrial cancer shown to be effective

In a randomized clinical trial, researchers from Huntsman Cancer Institute at the University of Utah (the U) have found that short-course, higher dose vaginal brachytherapy for endometrial cancer had similar effectiveness to more frequent, lower dose sessions.

11 Feb 2025

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025

New light-sensitive chemicals show promise for treating aggressive breast cancers

Scientists have developed new light-sensitive chemicals that can radically improve the treatment of aggressive cancers with minimal side effects.

11 Feb 2025

Study shows a clear causal relationship between gut microbiota and vagal nerve activity

A new study in an animal model provides direct evidence for the role of the vagus nerve in gut microbiome-brain communication, addressing a critical gap in the field.

11 Feb 2025

UVA launches trial to test AI-powered device for diabetes management

For people living with Type 1 Diabetes (T1D), keeping blood sugar levels in check is a constant challenge.

11 Feb 2025

Air pollution harms cognition just hours after exposure, study finds

New research shows that inhaling polluted air for just an hour can impair cognitive abilities like attention and emotional recognition within four hours, highlighting the urgent need for cleaner air policies.

11 Feb 2025

Study challenges belief that vaping leads to youth smoking

A team of public health researchers found "very low-certainty evidence" to support a commonly held belief that nicotine vaping is a gateway to cigarette smoking for young people.

11 Feb 2025

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025

Insilico Medicine announces preclinical drug discovery benchmarks from 2021 to 2024

Insilico Medicine ( "Insilico") , a clinical stage generative artificial intelligence (AI)-driven biotechnology company today announced a set of preclinical drug discovery benchmarks from the 22 developmental candidate nominations achieved by its platform from 2021 to 2024.

11 Feb 2025