Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Tumorigenesis may be induced from neighboring tissues, study suggests

Current view is that cancer development is initiated from cells that acquire initial DNA mutations. These in turn provoke additional defects, and ultimately the affected cells begin to proliferate in an uncontrolled manner to develop primary tumors.

2 Jun 2017

Microbiologist explores new methods for analyzing fecal pollution in water

In a project supported by the Austrian Science Fund FWF, the microbiologist Andreas Farnleitner is looking at new methods for analyzing faecal pollution in water. Using DNA analytics, the scientist aims to develop comprehensive and simple methods to determine the extent and origin of faecal pollution.

2 Jun 2017

ATCC and One Codex form partnership to address microbiome research needs

ATCC, a global leader in biological materials development, management and standards, and One Codex, a leading microbial genomics and metagenomics platform, today announced the formation of a partnership to address microbiome research needs.

2 Jun 2017

Insilico Medicine launches personalized drug discovery platform to develop new treatments for ALS

Today, Insilico Medicine, Inc., a company applying the latest advances in deep learning to biomarker development, drug discovery and aging research, launched ALS.AI, a personalized drug discovery and biomarker development platform utilizing the latest advances in deep learning.

1 Jun 2017

Study finds two genetic variants linked to bicuspid aortic valve development

Researchers are working to determine why the aortic valve doesn't form correctly in patients with the most common congenital heart defect: bicuspid aortic valve.

25 May 2017

BU professor receives Research Innovation and Translation Achievement Award from ATS

Avrum Spira, MD, MSc, professor of medicine, pathology and bioinformatics at Boston University School of Medicine, is the inaugural recipient of the Research Innovation and Translation Achievement Award from the American Thoracic Society.

24 May 2017

New study identifies 16 additional genetic markers linked to psoriasis

It's one of the most common immune-mediated diseases in the U.S., causing red, patchy and scaly marks on the skin. Yet the 1 to 2 percent of the population who have psoriasis are still left to wonder why.

24 May 2017

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences.

23 May 2017

WPI research program aims to understand gender differences in neurobiology

Many complicated neurological disorders appear to have a gender bias. Women, for example, are more likely to develop Alzheimer's disease, while men are at greater risk for Parkinson's disease.

17 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

By applying a novel computer algorithm to mimic how the brain learns, a team of researchers – with the aid of the Comet supercomputer based at the San Diego Supercomputer Center at UC San Diego and the Center's Neuroscience Gateway – has identified and replicated neural circuitry that resembles the way an unimpaired brain controls limb movement.

11 May 2017

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Researchers have identified a metabolite 'signature' that can accurately distinguish typhoid from other fever-inducing tropical diseases using patient blood samples.

9 May 2017

Researchers develop fast algorithm that provides new insights into protein evolution

Understanding evolution is one of the cornerstones of biology - evolution is, in fact, the sole explanation for life's diversity on our planet.

9 May 2017

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

In a new study, Roswell Park Cancer Institute researchers have demonstrated that an approach shown to improve outcomes for patients receiving colorectal surgery is just as effective in patients requiring many other abdominal and pelvic operations.

5 May 2017

Vitamin A deficiency leads to loss of blood stem cells

Many specialized cells, such as in the skin, gut or blood, have a lifespan of only a few days. Therefore, steady replenishment of these cells is indispensable. They arise from so-called "adult" stem cells that divide continuously.

5 May 2017

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

10x Genomics, a company focused on enabling the mastery of biology by accelerating genomic discovery, today announced publication of an article in the journal Nature of a collaborative research study with researchers at the Stanford University School of Medicine.

From 10x Genomics, Inc. 4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Invivoscribe® Technologies Inc., a global company with more than 20 years of experience providing clonality and biomarker test solutions for the fields of oncology, personalized molecular diagnostics® and personalized molecular medicine®, today announces the premarket approval of LeukoStrat® CDx FLT3 Mutation Assay.

3 May 2017

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

A new $2.4-million program for graduate students seeking to contribute to breakthrough discoveries in medicine and biology has been established at Penn State University with nearly $1.4 million in funding from the National Library of Medicine of the U.S. National Institutes of Health and more than $1 million from Penn State.

28 Apr 2017

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Scientists and physicians at University of California San Diego School of Medicine, working with colleagues at the U.S. Navy Medical Research Center - Biological Defense Research Directorate, Texas A&M University, a San Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages -- viruses that target and consume specific strains of bacteria -- to treat a patient near death from a multidrug-resistant bacterium.

25 Apr 2017

Bioinformatics News and Research

Further Reading

Tumorigenesis may be induced from neighboring tissues, study suggests

Microbiologist explores new methods for analyzing fecal pollution in water

ATCC and One Codex form partnership to address microbiome research needs

Insilico Medicine launches personalized drug discovery platform to develop new treatments for ALS

Study finds two genetic variants linked to bicuspid aortic valve development

BU professor receives Research Innovation and Translation Achievement Award from ATS

New study identifies 16 additional genetic markers linked to psoriasis

Study points to new pharmacologic approach to target chemo-resistant lung cancer

WPI research program aims to understand gender differences in neurobiology

Researchers identify many dangerous strains of TB pathogens

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

Metabolite 'signatures' can accurately distinguish typhoid from other fever-inducing diseases

Researchers develop fast algorithm that provides new insights into protein evolution

Study shows clear benefit from ERAS approaches in abdominal and pelvic surgeries

Vitamin A deficiency leads to loss of blood stem cells

New study uses 10x Genomics’ Single Cell 3’ Solution to unravel stem cell self-renewal mechanism

New research uncovers role of mysterious molecule in skin cancer

Invivoscribe receives FDA approval for the LeukoStrat CDx FLT3 mutation assay companion diagnostic test for the selection of patients for Rydapt

Penn State establishes new $2.4-million Biomedical Big Data to Knowledge Training Program

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

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