Efficacy News and Research

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Prescription trends for obesity medications surge, tied to growing interest in GLP-1 drugs

Obesity medication prescriptions reached 1.5 million, driven by GLP-1 agents semaglutide and tirzepatide, as public interest influences prescription trends.

3 Feb 2025

Study reveals mechanism behind CAR molecule transfer in cancer therapy

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumour microenvironment.

3 Feb 2025

Pain coping skills training reduces pain and improves quality of life for dialysis patients

People undergoing hemodialysis treatment for kidney failure often experience chronic pain related to their condition, but it can be difficult to manage with opioid medication and other conventional treatments.

31 Jan 2025

NIH-supported clinical trial to test experimental treatment for dengue

A clinical trial supported by the National Institutes of Health (NIH) is testing an experimental treatment designed to help people suffering the effects of dengue, a mosquito-borne viral disease.

31 Jan 2025

Emerging antibiotics at risk of resistance before clinical use

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Ventilation and air cleaners may increase aerosol spread in hospitals

Increased use of ventilation and air cleaners, designed to mitigate the spread of viral infections in hospitals, is likely to have unpredictable effects and may cause viral particles to move around more, according to a new study from researchers at UCL and UCLH.

31 Jan 2025

Antibody therapy provides protection against severe H5N1 avian flu in monkeys

A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, University of Pittsburgh and NIH Vaccine Research Center researchers report today in Science.

30 Jan 2025

PROTAC technology offers hope for treating castration-resistant prostate cancer

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men.

30 Jan 2025

Stem cell-derived heart patches show promise for heart failure treatment

Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a human patient, with trials ahead.

30 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

The key to healthy aging? Exercise might be the answer

Researchers explore the health benefits of physical activity in the elderly.

30 Jan 2025

Three new drug regimens offer hope for drug-resistant tuberculosis

Tuberculosis remains one of the top infectious disease killers worldwide, a challenge amplified by drug-resistant forms of the disease.

29 Jan 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

New study compares dementia care approaches and the impact on caregivers

New research comparing different approaches to dementia care for people with Alzheimer's disease and other dementias found no significant differences in patient behavioral symptoms or caregiver strain, whether delivered through a health system, provided by a community-based organization, or as usual care over an 18-month period.

29 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

Weekly diabetes injection could replace daily shots for lipodystrophy patients

Rutgers Health researchers have found that a weekly injection of diabetes medication could replace painful daily hormone shots for people with a rare genetic form of lipodystrophy that leaves patients with almost zero fat tissue, according to a study in The New England Journal of Medicine.

29 Jan 2025

Self-guided family-based treatment effective for childhood obesity

Family-based behavioral treatment (FBT) is a clinically-proven approach to treating children with obesity in which a health care professional works with the family to help children lose weight by promoting physical activity, encouraging healthy eating habits, and teaching age-appropriate behavioral skills.

29 Jan 2025

Survey reveals shift in U.S. views on childhood vaccine requirements

With President Donald Trump having threatened school vaccine mandates for children during his campaign, a new survey finds that nearly three-quarters of U.S. adults support requiring that children be vaccinated against preventable diseases such as measles, mumps, and rubella.

29 Jan 2025

Oral fecal transplantation could help prevent graft-versus-host disease in stem cell transplant patients

A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood cancers.

28 Jan 2025