Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Researchers investigate whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused hyperglycemia.

18 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Research investigates the potential health benefits of grape consumption by examining its impact on the human microbiome. By analyzing microbiome composition and metabolites, the study provides insights into the relationship between grapes and human health.

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

Can beer intake improve heart health following oxidative injury?

Researchers examined the impact of antioxidants found in fermented beverages on tissue transcriptomics.

16 May 2023

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

A new international study published in Nature Medicine and presented as a late-breaking abstract at the American Association of Neurological Surgeons annual conference, shows great promise for patients with glioblastoma.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Dietary recommendations for cardiovascular health challenged by new evidence on saturated fatty acids' effects on LDL-C and Lp(a) levels

Researchers discussed current dietary recommendations to reduce the intake of saturated fatty acids.

15 May 2023

Using an intracellular toolkit to map organelle bio-geography in stem cells

Organelles – the bits and pieces of RNA and protein within a cell – play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy.

12 May 2023

Targeting the hemoglobin problem in sickle cell disease using a new drug

A class of drugs used for their ability to stop tumor cells from dividing is now under study for their potential to reduce the pain and damage caused by sickle cell disease, investigators report.

11 May 2023

How eating mushrooms may lower blood pressure levels

Scientists review the potential of edible mushrooms as functional foods in improving cardiovascular function and ameliorating hypertension.

11 May 2023

Study extends understanding of m6A modification as biological pathway underlying atrial fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Numerous single nucleotide polymorphisms (SNPs) have been identified as genetic contributors to atrial fibrillation (AF).

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

New approaches to promote healthspan from an epigenetic perspective

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "How can we modulate aging through nutrition and physical exercise? An epigenetic approach."

10 May 2023

Study may provide new avenues for addressing somatosensory symptoms of long COVID

COVID-19, the disease resulting from SARS-CoV-2 infection, is associated with highly variable clinical outcomes that range from asymptomatic disease to death.

9 May 2023

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers investigated whether functional connectivity between glioblastoma and the brain affected neural circuits.

9 May 2023

Can intermittent fasting tackle obesity-related inflammation?

Research reviews the effects of two forms of intermittent fasting, time-restricted eating (TRE) and alternate-day fasting (ADF), on body weight and key circulating inflammatory markers (CRP, TNF-alpha, and IL-6) in adults with obesity. The results suggest that intermittent fasting has little or no effect on key inflammatory markers, but more research is needed to confirm these findings.

8 May 2023

Upregulated expression of many LY6 genes linked to poor survival in endometrial cancer patients

A new research paper was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma."

8 May 2023

Gene Expression News and Research

Further Reading

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Researchers find that SARS-CoV-2 directly infects hepatocytes that cause hyperglycemia

Democratizing RNA sequencing: A breakthrough in cost and efficiency

Grape expectations: Dietary grapes promote subtle shifts in human microbiome with potential health implications

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

Can beer intake improve heart health following oxidative injury?

Clinical trial of a combination treatment shows great promise for patients with glioblastoma

Newly identified genetic variant provides protection from Alzheimer's disease

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Dietary recommendations for cardiovascular health challenged by new evidence on saturated fatty acids' effects on LDL-C and Lp(a) levels

Using an intracellular toolkit to map organelle bio-geography in stem cells

Targeting the hemoglobin problem in sickle cell disease using a new drug

How eating mushrooms may lower blood pressure levels

Study extends understanding of m6A modification as biological pathway underlying atrial fibrillation

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

New approaches to promote healthspan from an epigenetic perspective

Study may provide new avenues for addressing somatosensory symptoms of long COVID

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Can intermittent fasting tackle obesity-related inflammation?

Upregulated expression of many LY6 genes linked to poor survival in endometrial cancer patients

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