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SARS-CoV-2 surveillance in urban wildlife from Ontario and Québec

Researchers conducted SARS-CoV-2 surveillance in urban wildlife from Ontario and Québec, Canada.

7 Dec 2021

Simple quantitative framework to understand the pathogenesis of severe COVID-19

Researchers from Los Alamos National Laboratory in the United States developed a model to explain why severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections induce high inflammatory levels.

6 Dec 2021

'Combination' adjuvant may boost the protective power of vaccines

Scientists at La Jolla Institute for Immunology and Massachusetts Institute of Technology, have found a possible way to improve the effectiveness of COVID-19 vaccines - and any vaccine.

4 Dec 2021

In-depth analysis of SARS-CoV-2 specific T cells in unexposed individuals

A new study aimed to analyze SARS-CoV-2 specific T-cells in unexposed individuals.

2 Dec 2021

Special collection of articles highlights China's response to covid-19

Today, The BMJ is launching a special collection of articles on China's response to covid-19 - what it was, how it worked, why traditional public health measures played such a vital role, and how other countries can learn from this experience to protect their populations, in particular in future pandemics.

2 Dec 2021

Novel approach to estimate transmission advantage of SARS-CoV-2 variants in real-time

A new study retrospectively estimates the effective transmission advantage of the Alpha variant as compared to other non-VOC lineages.

1 Dec 2021

Grouping of immunological T-cell receptors may be key to identifying patients' history of infection

Grouping of pathogen-recognizing proteins on immune T cells may be key to identifying if someone has had an infection in the past, suggests a study published today in eLife.

1 Dec 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Scientists develop a smartwatch-based device for early detection of COVID-19

Scientists have developed a wearable device that can detect the early onset of COVID-19 in real-time by analyzing the aberrant changes in physiological parameters caused by SARS-CoV-2 infection.

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Extended host range for SARS-CoV-2 variants of concern

Researchers used viral pseudotyping to examine whether variants of concern had different host ACE2 receptor usage patterns.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Prediction of severe infection based on SARS-CoV-2 genomic analysis

A group of researchers have used these SARS-CoV-2 sequence data and developed an algorithm to predict severity based upon viral mutations.

26 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

Mtb's exotoxin secretion and trafficking mechanism revealed

Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years.

25 Nov 2021

Adoption of a robust approach to minimize disease transmission between humans and wild animals

The threat of disease transmission from conservationists moving wild animals between habitats or back into the wild needs to be urgently assessed to minimize risk.

25 Nov 2021

Maternal-fetal interface yields intriguing clues to how it battles SARS-CoV-2

Scientists have hypothesized that the number of immune cells and the amount of cytokines produced in response to SARS-CoV-2 infection in pregnant women change in accordance with the timing of maternal infection in pregnancy. This study is available on the bioRxiv* preprint server.

24 Nov 2021

Drug-resistant bacteria are quickly outpacing new antibiotic development

Experts predict that without intervention, the problem of multidrug-resistant bacterial infections could be catastrophic by 2050, killing nearly 10 million people each year.

24 Nov 2021