Pathology News and Research

RSS

Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Antiviral protein protects against COVID-19 in live mouse models

A mammalian protein previously shown by UT Southwestern microbiologists to inhibit the virus that causes COVID-19 in cell culture also protected live mouse models, significantly limiting infection in the lung cells and diminishing the symptoms.

1 Aug 2023

Investigating the neurological effects of SARS-CoV-2: anosmia and neuroinvasion as separate phenomena

A group of researchers investigated the neurotropic potential of SARS-CoV-2 and its variants by studying their ability to invade the brain through the olfactory pathway in hamsters.

1 Aug 2023

Human senescent fibroblasts trigger fibrogenic reaction in the lungs of immunodeficient mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Human senescent fibroblasts trigger progressive lung fibrosis in mice."

31 Jul 2023

Low levels of 'memory strengthening protein' may serve as early predictor of mild cognitive impairment

Results of a long-term, federally funded study of cognitively healthy adults — most with a family history of Alzheimer's disease — have added to evidence that low spinal fluid levels of a protein linked to learning and memory in mice may serve as an early predictor of mild cognitive impairment (MCI) years before symptoms appear.

31 Jul 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Mutational accessibility: A key driver of viral evolution

The influenza (flu) virus is constantly undergoing a process of evolution and adaptation through acquiring new mutations.

29 Jul 2023

Researchers seek to understand the Achilles' heel of insulin pump technology

Since the insulin pump started widespread use in the early 1980s, it's become the option of choice for type 1 diabetes patients to manage their glucose levels in a way that doesn't require testing their blood sugar and injecting insulin multiple times daily.

27 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

Study finds high rates of illicit drug use in young adults who experienced sudden cardiac death

Approximately one-third of young adults in Victoria, Australia, who experienced sudden cardiac deaths (SCDs) outside of a hospital setting from April 2019 to April 2021 used illegal drugs prior to their fatal events, reports a new study in Heart Rhythm, the official journal of the Heart Rhythm Society, the Cardiac Electrophysiology Society, and the Pediatric & Congenital Electrophysiology Society, published by Elsevier.

27 Jul 2023

Lab-on-a-chip technologies offer new ways to assess stored red blood cells

Ziya Isiksacan, PhD, a research fellow in the Center for Engineering in Medicine and Surgery (CEMS) is the lead author, and Osman Berk Usta, PhD, an investigator in the CEMS at Massachusetts General Hospital and an associate professor of Surgery at Harvard Medical School, is the senior author of a new study published in PNAS, Assessment of Stored Red Blood Cells Through Lab-on-a-Chip Technologies for Precision Transfusion Medicine.

26 Jul 2023

Positive experiences can reverse cognitive decline in old age

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "MSK1 is required for the beneficial synaptic and cognitive effects of enriched experience across the lifespan."

26 Jul 2023

Study reveals new way to slow progression of Alzheimer's disease

A new study by researchers at Case Western Reserve University revealed that the progression of Alzheimer's disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion.

24 Jul 2023

Generating functional parathyroid glands from mouse embryonic stem cells

Regenerative medicine has opened up exciting possibilities in the world of medicine. Now, researchers in Japan are searching for ways to recreate and rebuild body tissues and organs, which may be an alternative cure for diseases.

24 Jul 2023

Improving gut health may be key to slowing HIV progression to AIDS

Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.

24 Jul 2023

New biomarkers could help identify aggressive prostate cancer

UniSA researchers have identified three new biomarkers for prostate cancer to help identify and differentiate potentially aggressive cases of the disease which kills more than 300,000 men each year.

24 Jul 2023

Muscle-building supplement may help protect memory and prevent Alzheimer's disease

The secret to protecting your memory may be a staple of a bodybuilder's diet. RUSH researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer's disease.

21 Jul 2023