Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

New blood test detects genetic disorders in fetuses

Tel Aviv University researchers have developed a new blood test for genetic disorders that may allow parents to learn about the health of their baby as early as 11 weeks into pregnancy.

21 Feb 2019

Rubicon level linked to inhibition of autophagic process

Autophagy is an important biological recycling mechanism that is used to maintain homeostasis within all types of animal tissue. Many studies have attempted to understand the relationship between the reduction of autophagy and progression of aging in animals; however, none have provided a clear explanation, until now.

20 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

$4.1 million funding for heart research on Valentine's Day

Valentine's Day is a time to celebrate love and romance, but the holiday has also become an opportunity to promote heart health, a tradition that continues as Clemson University bioengineers announce the launch of two separate research projects.

14 Feb 2019

New method detects potentially disease-causing forms of proteins using fluorescence

A new method uses fluorescence to detect potentially disease-causing forms of proteins as they unravel due to stress or mutations.

14 Feb 2019

Researchers provide insight into how breast tissue stiffening promotes cancer development

A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells.

13 Feb 2019

Study findings hold promise for children with DMD

Prednisone, the current standard of care used to treat kids with Duchenne muscular dystrophy (DMD), reduces chronic inflammation but has harsh side effects.

11 Feb 2019

Bone marrow disease is stimulated by vitamin D and immune cells, reveals research

The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes.

11 Feb 2019

New research opens the way for tailored cancer drugs

New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer.

11 Feb 2019

New study pinpoints how fibrosis develops in butterfly syndrome patients

Children with a grave skin disorder known as butterfly syndrome develop severe and chronic blisters. Fibrosis, the thickening and scarring of connective tissues, is a major complication of the disease.

7 Feb 2019

Research could provide a new way to treat organ scarring in future

The increased deposition of connective tissue is a problem in chronic diseases of many organs such as the lungs, liver, kidneys, gut, and the skin.

6 Feb 2019

Study uncovers new clues to lung transplant rejection

A lung transplant often remains the only option for many patients with end-stage lung disease, a condition that can be brought on by emphysema, pulmonary fibrosis, cystic fibrosis and other lung disorders.

4 Feb 2019

The T2B Infrastructure Center for Respiratory Disease set to enter into the final phase

The Korea Institute of Toxicology (KIT·Chief Dr. Song, Chang-woo) National Center for Efficacy Evaluation of Respiratory Disease Product (NCER·Chief Dr. Lee, Kyu-hong) obtained on January 10 the final decision from the Ministry of Health and Welfare that the T2B Infrastructure Center for Respiratory Disease would enter into the final phase (second phase) with funding of 3 billion KRW over two years.

4 Feb 2019

New clinical practice guideline on home oxygen therapy for children

The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society's American Journal of Respiratory and Critical Care Medicine.

4 Feb 2019

Discovery of proteins that control mucin secretion reveals clues to treating colon, airway diseases

Cells produce mucins at a constant rate, and when exposed to an allergen or pathogen, they produce more mucin in a rapid burst. Both the constant and rapid mucin secretion is controlled by calcium.

1 Feb 2019

Cancer nanomedicine may accelerate metastasis, NUS study finds

Nanoparticles can be found in processed food (e.g. food additives), consumer products (e.g. sunscreen) and even in medicine. While these tiny particles could have large untapped potential and novel new applications, they may have unintended and harmful side effects, according to a recent study by researchers from the National University of Singapore.

1 Feb 2019

Research may provide a new way to treat organ scarring

Scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Medicine 3 - Rheumatology and Immunology, headed by Prof. Dr. Georg Schett, have now decrypted a molecular network that controls these processes and could in future provide a new way to treat organ scarring.

1 Feb 2019

Insilico to present its latest results in AI for Drug Discovery on CXOTalk Show

Insilico Medicine, a Rockville-based company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery on a live episode of the influential CXOTalk Show on February 8, 2019 at 1:00 PM Eastern time.

1 Feb 2019

Researchers identify new therapeutic targets for kidney fibrosis

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population--and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis.

29 Jan 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019