Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

A group of Portuguese researchers from IBMC and FMUP at the University of Porto has found the reason why patients with chronic pain often suffer from impaired short -term memory.

9 Feb 2013

Location of altered brain metabolite levels found in bipolar I patients

Bipolar I disorder patients have increased phospholipid levels in the thalami and increased N-acetyl-aspartate levels in the left hippocampus compared with healthy individuals, a team of investigators has discovered.

5 Feb 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

2 Feb 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

31 Jan 2013

Scientists discover clear link between poor sleep, memory loss and brain deterioration of old age

The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory.

28 Jan 2013

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

Using a brain-imaging technique that examines the entire infant brain, researchers have found that the anatomy of certain brain areas - the hippocampus and cerebellum - can predict children's language abilities at 1 year of age.

22 Jan 2013

Family members with rare gene mutation at high risk of developing schizophrenia

Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.

22 Jan 2013

New model of tau pathology spread

Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological tau filaments.

19 Jan 2013

Dentate gyrus, fimbria volumes reduced in bipolar II disorder

Results from a Norwegian study suggest that the dentate gyrus and fimbria may play an important role in the pathophysiology of bipolar II disorder.

17 Jan 2013

Pannexin1 channel protein critical for memory and orientation

The channel protein Pannexin1 keeps nerve cells flexible and thus the brain receptive for new knowledge. Together with colleagues from Canada and the U.S., researchers at the Ruhr-Universit-t Bochum led by the junior professor Dr. Nora Prochnow from the Department of Molecular Brain Research describe these results in PLoS ONE.

10 Jan 2013

Study investigates prolonged pathological outcomes of traumatic brain injury

Researchers from the University of South Florida and colleagues at the James A. Haley Veterans' Hospital studying the long-term consequences of traumatic brain injury using rat models, have found that, overtime, TBI results in progressive brain deterioration characterized by elevated inflammation and suppressed cell regeneration.

7 Jan 2013

Women with menopausal transition experience cognitive difficulties

The memory problems that many women experience in their 40s and 50s as they approach and go through menopause are both real and appear to be most acute during the early period of post menopause. That is the conclusion of a study which appears today in the journal Menopause.

4 Jan 2013

NIDA's 2012 Monitoring the Future survey shows rates stable or down for most drugs

Continued high use of marijuana by the nation's eighth, 10th and 12th graders combined with a drop in perceptions of its potential harms was revealed in this year's Monitoring the Future survey, an annual survey of eighth, 10th, and 12th-graders conducted by researchers at the University of Michigan.

20 Dec 2012

Ion channel acts as powerful ‘brake’ after epileptic seizures

Given that epilepsy impacts more than 2 million Americans, there is a pressing need for new therapies to prevent this disabling neurological disorder. New findings from the neuroscience laboratory of Mark S. Shapiro, Ph.D., at The University of Texas Health Science Center at San Antonio, published Dec. 20 in the high-impact scientific journal, Neuron, may provide hope.

19 Dec 2012

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

The University of North Carolina at Chapel Hill has awarded the 13th Perl-UNC Neuroscience prize jointly to Edvard and May-Britt Moser at the Norwegian University of Science and Technology (NTNU-Trondheim) in Trondheim, Norway.

17 Dec 2012

Relatives of schizophrenia patients show cortical thinning

Patients with schizophrenia and their unaffected relatives show significant cortical thinning compared with mentally healthy individuals without such a family history, researchers report.

13 Dec 2012

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

Researchers at Johns Hopkins Medicine in November surgically implanted a pacemaker-like device into the brain of a patient in the early stages of Alzheimer's disease, the first such operation in the United States. The device, which provides deep brain stimulation and has been used in thousands of people with Parkinson's disease, is seen as a possible means of boosting memory and reversing cognitive decline.

6 Dec 2012

UI researchers develop neonatal piglet model to study micronutrient deficiencies

University of Illinois researchers have developed a model that uses neonatal piglets for studying infant brain development and its effect on learning and memory. To determine if the model is nutrient-sensitive, they have done some research on the effects of iron-deficient diets.

4 Dec 2012

Long-term hippocampal DBS effectively reduces seizures in experimental models

The results of the first reported study of deep brain stimulation (DBS) in an animal model for temporal lobe epilepsy (TLE) presented today at the American Epilepsy Society (AES) 66th Annual Meeting suggests that DBS may have potential as therapy for this common and often difficult to treat form of epilepsy.

2 Dec 2012

Hippocampus News and Research

Further Reading

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

Location of altered brain metabolite levels found in bipolar I patients

Review article highlights growing evidence for lasting impact of alcohol on the brain

Review article highlights growing evidence for lasting impact of alcohol on the brain

Scientists discover clear link between poor sleep, memory loss and brain deterioration of old age

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

Family members with rare gene mutation at high risk of developing schizophrenia

New model of tau pathology spread

Dentate gyrus, fimbria volumes reduced in bipolar II disorder

Pannexin1 channel protein critical for memory and orientation

Study investigates prolonged pathological outcomes of traumatic brain injury

Women with menopausal transition experience cognitive difficulties

NIDA's 2012 Monitoring the Future survey shows rates stable or down for most drugs

Ion channel acts as powerful ‘brake’ after epileptic seizures

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

Relatives of schizophrenia patients show cortical thinning

First U.S. patient treated with deep brain stimulation for Alzheimer's at Johns Hopkins

UI researchers develop neonatal piglet model to study micronutrient deficiencies

Long-term hippocampal DBS effectively reduces seizures in experimental models

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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