Immune System News and Research

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Study confirms overuse of blood transfusions during surgery

Citing the lack of clear guidelines for ordering blood transfusions during surgery, Johns Hopkins researchers say a new study confirms there is still wide variation in the use of transfusions and frequent use of transfused blood in patients who don't need it.

25 Apr 2012

Oregano ingredient could treat prostate cancer

Oregano, the common pizza and pasta seasoning herb, has long been known to possess a variety of beneficial health effects, but a new study by researchers at Long Island University (LIU) indicates that an ingredient of this spice could potentially be used to treat prostate cancer, the second leading cause of cancer death in American men.

25 Apr 2012

Vitamin D deficiency associated with increase in lung transplant rejection, infections

Vitamin D deficiency is associated with an increase in lung transplant rejection and infections, according to research conducted at Loyola University Health System.

25 Apr 2012

Researchers discover how dendritic cells exchange information to amplify immune response

Using a new fluorescent biosensor they developed, researchers at Carnegie Mellon University have discovered how a key set of immune cells exchange information during their coordinated assault on invading pathogens.

24 Apr 2012

Immunosignatures can yield reliable and highly stable diagnostic results

Identifying diseases at an early, presymptomatic stage may offer the best chance for establishing proper treatment and improving patient outcomes. A new technique known as immunosignaturing harnesses the human immune system as an early warning sentry-one acutely sensitive to changes in the body that may be harbingers of illness.

24 Apr 2012

Researchers describe novel mechanism of HIV-1 spread by dendritic cells

A new understanding of the initial interactions of human immunodeficiency virus type 1 (HIV-1) and dendritic cells is described by Boston University School of Medicine (BUSM) researchers in a study currently featured in the Proceedings of the National Academy of Sciences.

24 Apr 2012

Cancer therapy with common cold virus

Common viruses have become the latest weapon against cancer. There is the case of the eight-year-old African boy diagnosed with Burkitt's lymphoma at a Ugandan health clinic. He was exposed to the measles virus and in the next few weeks his tumour regressed completely and he entered remission. But only relatively recently have scientists clinically examined the interaction between viruses and cancers in the growing area of oncolytic virotherapy.

24 Apr 2012

HDAC6 protein may provide novel target for stress-linked disorders

A cellular protein called HDAC6, newly characterized as a gatekeeper of steroid biology in the brain, may provide a novel target for treating and preventing stress-linked disorders, such as depression and post-traumatic stress disorder (PTSD), according to research from the Perelman School of Medicine at the University of Pennsylvania.

24 Apr 2012

Study explains association between alcohol consumption and breast cancer

A research team this week will present findings that they say may finally explain the link between alcohol consumption and breast cancer.

24 Apr 2012

Beta cells from genetically modified pigs can effectively restore pancreas function

Transplantation of a whole pancreas or isolated insulin-producing beta cells are the only therapy to cure type 1 diabetes. However, the shortage of organ donors limits this approach to only few patients. LMU researchers have now shown that beta cells from genetically modified pigs can effectively restore pancreas function and can protect porcine beta cells from immune rejection in animal models.

23 Apr 2012

BAMC/SAMMC researcher develops microemulsion vaccine carrier

A researcher at the Brooke Army Medical Center (BAMC)/San Antonio Military Medical Center (SAMMC) will present findings this week on a new potential vaccine carrier that he hopes will extend the shelf life of and aid in the stockpiling of critical vaccines.

23 Apr 2012

Autophagy potential target for new CF treatments

Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.

23 Apr 2012

Study shows how MRSA epidemics may emerge and spread at molecular level

National Institutes of Health (NIH) scientists and their colleagues in China have described a rapidly emerging Staphylococcus aureus gene, called sasX, which plays a pivotal role in establishing methicillin-resistant S. aureus (MRSA) epidemics in most of Asia.

23 Apr 2012

New drug can prevent exacerbations of asthma due to common cold: Trial report

For the tens of thousands of asthma sufferers in the UK there is a “breakthrough” drug that reduces complications caused by the common cold, it is claimed.

22 Apr 2012

Scientists identify link between different strains of malaria parasites

Scientists have identified a link between different strains of malaria parasites that cause severe disease, which could help develop vaccines or drugs against life-threatening cases of the infection.

21 Apr 2012

NSF announces 2012 Graduate Research Fellows

From cognitive neuroscience to theoretical physics, this year's National Science Foundation (NSF) Graduate Research Fellows from the University of Houston (UH) have their sights set on careers in fields ranging from medicine to energy.

21 Apr 2012

Scientists discover tumor-targeting neural stem cells

Could engineered human stem cells hold the key to cancer survival? Scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, have discovered that neural stem cells possess the innate ability to target tumor cells outside the central nervous system. This finding, which was demonstrated successfully on breast cancer cells, was recently published in leading peer reviewed journal, Stem Cells.

21 Apr 2012

Researchers discover novel genetic mechanism of idiopathic CD4 lymphopenia

Researchers at National Jewish Health have discovered a novel genetic mechanism of immune deficiency. Magdalena M. Gorska, MD, PhD, and Rafeul Alam, MD, PhD, identified a mutation in Unc119 that causes immunodeficiency known as idiopathic CD4 lymphopenia.

21 Apr 2012

Nanoscale films promote bone growth

Every year, more than a million Americans receive an artificial hip or knee prosthesis. Such implants are designed to last many years, but in about 17 percent of patients who receive a total joint replacement, the implant eventually loosens and has to be replaced early, which can cause dangerous complications for elderly patients.

20 Apr 2012

Study supports previously reported positive links between vitamin D and testosterone

A new study conducted by the Harvard School of Public Health, released in the Journal of Clinical Endocrinology, suggests that maintaining a high level of vitamin D supplementation increases the level of testosterone in men.

20 Apr 2012