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Uncovering the neurobiological mechanisms of delta opioid receptor agonists

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, including slow action and adverse effects with long-term use. This underscores the urgent need for novel, rapidly-acting therapeutic agents with minimal side effects.

15 Jan 2025

Research reveals inaccuracies in common gene therapy measurement technique

In a finding with implications for one of the most promising cutting-edge medical treatments, researchers evaluated several measurement techniques commonly used in gene therapy.

13 Jan 2025

Study reveals decline in hormonal contraceptive use and increase in fertility awareness methods

There has been a shift away from the use of more reliable hormonal methods of contraception to less reliable fertility awareness methods among women requesting abortion in England and Wales over the past 5 years, reveals research published online in the journal BMJ Sexual & Reproductive Health.

13 Jan 2025

COVID-19 vaccine developed by Brazilian researchers shows promise in mice

Studies conducted in mice have shown that the COVID-19 vaccine being developed by researchers at the University of São Paulo's Medical School (FM-USP) in Brazil is safe and efficacious.

13 Jan 2025

Study highlights the need for clearer diagnosis and treatment of preschool wheeze

A study led by Aston University's Dr Gemma Heath and Dr Prasad Nagakumar from Birmingham Children's Hospital, has shown that treatment and diagnosis for preschool wheeze needs more effective evidence-based guidelines.

13 Jan 2025

Scientists discover why cancer cells die differently after radiotherapy

Scientists at Children's Medical Research Institute have solved a big mystery in cancer research – why cells die in different ways following radiotherapy.

13 Jan 2025

The Rise of Ionized Hydrogen Peroxide (iHP) in Modern Disinfection

Discover the benefits of ionized hydrogen peroxide for disinfection. Jim Reynolds shares expert insights on its applications and impact on industry standards.

From SteraMist Disinfection and Decontamination Technology 13 Jan 2025

Totally implantable cochlear implant promises a new era of hearing restoration

Scientists have developed a totally implantable cochlear implant that delivers hearing performance comparable to conventional devices while improving quality of life and eliminating the need for external components.

12 Jan 2025

European research project seeks faster depression treatment solutions

Depression can affect anyone. It is common, and in many cases severe. These days, there are good treatments available, typically involving a combination of psychotherapy and medication.

10 Jan 2025

Innovative tablet combination shows promise in fighting Trichuris trichiura and other helminths

A new tablet combining albendazole and ivermectin is safe and more effective than albendazole alone in treating Trichuris trichiura and other soil-transmitted helminths (STH), according to a clinical trial conducted by the STOP consortium and led by the Barcelona Institute of Global Health (ISGlobal), a centre supported by "la Caixa" Foundation.

10 Jan 2025

Menarini Group signs licensing deal with Insilico for promising cancer treatment

The Menarini Group ("Menarini"), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. ("Stemline"), a wholly-owned subsidiary of the Menarini Group focused on bringing transformational oncology treatments to cancer patients, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the companies have entered into an exclusive licensing agreement granting Stemline the global rights to develop and commercialize a preclinical small molecule targeting high unmet needs in oncology.

10 Jan 2025

T cells can completely prevent viral infections in humans

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

10 Jan 2025

HIV drug access remains a major challenge despite promising trial results

Promising new drugs to prevent and treat HIV have the potential to transform the response to the disease. But getting these drugs to those who need it most will be critical, says Beatriz Grinsztejn, president of the International AIDS Society.

10 Jan 2025

Machine learning reveals why cancer trials fall short in real-world patients

TrialTranslator uses machine learning to assess cancer RCT generalizability, revealing survival gaps for high-risk patients and enhancing research accuracy.

10 Jan 2025

New biomaterial could redefine recovery from brain and central nervous system injuries

A new electrically active transplantable material that can help to regrow cells in the brain and spinal cord could redefine the recovery prospects of patients who sustain life-altering injuries or suffer from neurodegenerative diseases.

10 Jan 2025

New therapeutic target could boost CAR T-cell therapy success in solid tumors

Russell W. Jenkins, MD, PhD, a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author of a new study in Cancer Immunology Research, "TBK1 is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids".

10 Jan 2025