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Targeting the Hippo signaling pathway to treat systemic sclerosis

Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.

21 Feb 2024

Pioneering cell-based treatment for melanoma offered at Siteman Cancer Center

Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.

20 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

NIH-funded research enhances genetic testing for health equity

To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score.

20 Feb 2024

New RNA therapy zilebesiran shows promise in lowering blood pressure

Zilebesiran, an RNA interference therapeutic, significantly reduces blood pressure in hypertension patients with a favorable safety profile, offering a potential biannual treatment option.

19 Feb 2024

Selection, optimization, and validation of genetic tests for 10 common diseases

By analyzing millions of small genetic differences across a person's genome, researchers can calculate a polygenic risk score to estimate someone's lifetime odds of developing a certain disease.

19 Feb 2024

Evaluating a machine learning tool for predicting hospital-acquired acute kidney injury

Hospital-acquired acute kidney injury (HA-AKI) is a common complication in hospitalized patients that can lead to chronic kidney disease and is associated with longer hospital stays, higher health care costs and increased mortality.

16 Feb 2024

Heart attack survivors face higher risk of long-term health conditions

Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows.

16 Feb 2024

6th CKD Drug Development Summit: Countdown Begins

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From 6th CKD Drug Development Summit 16 Feb 2024

Ketogenic diet boosts brain's natural calm to combat epilepsy

A study in Cell Discovery shows the ketogenic diet increases brain GABA levels and the GABA/glutamate ratio through β-hydroxybutyric acid, offering a potential mechanism for its effectiveness in reducing epilepsy seizures.

15 Feb 2024

Good news for Valentine’s Day: Dark chocolate and champagne may improve heart health

It’s news you’ll love for Valentine’s Day: a leading health expert says the dark chocolates and bubbly you bought your sweetheart may also improve their heart health.

13 Feb 2024

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

A therapist-guided digital cognitive behavioural therapy reduced distress in 89 per cent of participants living with long-term physical health conditions, a new King's College London study finds.

13 Feb 2024

Gene therapy reverses advanced heart failure in animal study

Heart failure remains the leading cause of mortality in the U.S. During a heart attack blood stops flowing into the heart.

13 Feb 2024

A century of progress: American Heart Association's historic journey and future directions

Dramatic advances in the understanding and treatment of cardiovascular diseases have saved millions of lives in the 100 years since the founding in 1924 of the American Heart Association, the world's leading voluntary organization focused on heart and brain health for all.

13 Feb 2024

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Heart disease is the leading cause of death among women, and women who have complications during pregnancy, such as high blood pressure or gestational diabetes, have a significantly higher risk of heart disease and stroke later in life, according to a new scientific statement from the American Heart Association, published today in Circulation, the Association's flagship peer-reviewed journal.

12 Feb 2024

Small ultrasound sticker can monitor the stiffness of internal organs

MIT engineers have developed a small ultrasound sticker that can monitor the stiffness of organs deep inside the body.

9 Feb 2024

UT Health San Antonio scientist receives $1.2 million to implement early intervention measures for pre-diabetes

More than one out of three people have pre-diabetes, characterized by abnormal blood sugar levels not yet in the diabetes range – and yet associated with significant increases in eye, kidney and neuropathic diseases, and risk of cardiovascular death.

8 Feb 2024

Healthcare providers' assumptions about parents' preferences hinder effective care for child diarrhea

Young children in India who suffer from life-threatening diarrhea frequently are given ineffective treatments because health providers misperceive the wishes of a child's caregiver, according to a novel new study.

8 Feb 2024

Weekly exercise may reduce chronic kidney disease risk in obese people with type 2 diabetes

Clocking up high weekly levels of moderate to vigorous intensity physical activity is linked to a lower risk of developing chronic kidney disease in overweight/obese people with type 2 diabetes, finds research published online in the British Journal of Sports Medicine.

8 Feb 2024

New study links legume consumption to lower risk of colorectal cancer

Researchers collated and analyzed 12 studies comprising more than 17 years’ worth of case-control experiments aimed at elucidating site-specific cancer outcomes of legume consumption.

8 Feb 2024

Kidney News and Research

Targeting the Hippo signaling pathway to treat systemic sclerosis

Pioneering cell-based treatment for melanoma offered at Siteman Cancer Center

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

NIH-funded research enhances genetic testing for health equity

New RNA therapy zilebesiran shows promise in lowering blood pressure

Selection, optimization, and validation of genetic tests for 10 common diseases

Evaluating a machine learning tool for predicting hospital-acquired acute kidney injury

Heart attack survivors face higher risk of long-term health conditions

6th CKD Drug Development Summit: Countdown Begins

Ketogenic diet boosts brain's natural calm to combat epilepsy

Good news for Valentine’s Day: Dark chocolate and champagne may improve heart health

Therapist-guided digital therapy reduces distress in people with long-term physical health conditions

Gene therapy reverses advanced heart failure in animal study

A century of progress: American Heart Association's historic journey and future directions

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Small ultrasound sticker can monitor the stiffness of internal organs

UT Health San Antonio scientist receives $1.2 million to implement early intervention measures for pre-diabetes

Healthcare providers' assumptions about parents' preferences hinder effective care for child diarrhea

Weekly exercise may reduce chronic kidney disease risk in obese people with type 2 diabetes

New study links legume consumption to lower risk of colorectal cancer

Free guide - Everything about renal proximal tubule cells eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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