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Clinical trial demonstrates safety of targeted treatment approach for deadly brain tumor in children

A Phase I clinical trial demonstrated that a targeted approach to treating a deadly brain tumor in children called diffuse intrinsic pontine glioma (DIPG) is safe, reported Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center investigators.

3 Apr 2025

New CT-based score helps predict need for repeat sinus surgery

A new CT-scan based risk score facilitates the identification of patients at risk of revision endoscopic sinus surgery due to chronic rhinosinusitis.

3 Apr 2025

What’s lost: Trump whacks tiny agency that works to make the nation’s health care safer

Sue Sheridan's baby boy, Cal, suffered brain damage from undetected jaundice in 1995. Helen Haskell's 15-year-old son, Lewis, died after surgery in 2000 because weekend hospital staffers didn't realize he was in shock.

3 Apr 2025

Addressing low lung cancer screening rates through awareness and access

Lung cancer screening has the potential to catch lung cancer early and save lives-but only if people get screened. Although lung cancer screening is recommended in the U.S. for certain individuals with a history of smoking, only 18% of eligible individuals in the U.S. get screened.

3 Apr 2025

Macular thickness could predict postoperative delirium in older patients

Thickening of the macular layer of the eye's retina is associated with a greater risk of postoperative delirium for older patients undergoing surgery under general anaesthetic, reveals a study published online in the open access journal General Psychiatry.

2 Apr 2025

Survey reveals high rate of NHS-related harm in Great Britain

Almost one in ten people in Great Britain experienced healthcare-related harm due to care or treatment they received from the National Health Service (NHS) or difficulties accessing care in the last three years, show the findings of a large population survey published in the journal BMJ Quality & Safety.

2 Apr 2025

How much will that surgery cost? 🤷 Hospital prices remain largely unhelpful.

It's a holy grail of health care: forcing the industry to reveal prices negotiated between health plans and hospitals — information that had long been treated as a trade secret.

2 Apr 2025

High-fat diet linked to increased breast cancer metastasis risk

Obesity is associated with an increased risk of developing breast cancer, and a greater probability for the cancer to spread to other organs – metastasize –. But the causes of this association are still not well understood.

2 Apr 2025

Scientists make breakthrough in understanding the causes of spina bifida

Scientists at Rady Children's Institute for Genomic Medicine, and the Department of Neurosciences and Pediatrics at the University of California, San Diego, have made a significant breakthrough in understanding the causes of spina bifida, a serious birth defect affecting thousands of newborns each year.

1 Apr 2025

Hydrogel-based drug delivery offers hope for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition.

1 Apr 2025

Gastric bypass proven most effective for severe obesity in landmark study

Gastric bypass is the most clinically and cost effective form of interventional surgery for people living with severe obesity, reveals landmark research funded and supported by the National Institute for Health and Care Research (NIHR).

1 Apr 2025

Scientists discover key genes for regenerating cells in the ear and eye

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the National Academy of Sciences (PNAS).

1 Apr 2025

Queen Mary scientists invent a new way to repair osteochondral defects

Scientists at Queen Mary University of London have invented a new way to repair osteochondral defects – a common form of joint damage often caused by sports injuries or trauma – and to prevent progression to osteoarthritis.

1 Apr 2025

New genetic discovery sheds light on PHTS-related vascular malformations

During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner.

31 Mar 2025

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Patients who underwent transcatheter aortic valve replacement (TAVR) with a valve designed to treat aortic regurgitation had an overall mortality rate of just 8.1% at one year, well below the trial's prespecified goal of 25% to show non-inferiority, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

‘They won’t help me’: Sickest patients face insurance denials despite policy fixes

Sheldon Ekirch spends a lot of time on hold with her health insurance company. Sometimes, as the minutes tick by and her frustration mounts, Ekirch, 30, opens a meditation app on her phone. It was recommended by her psychologist to help with the depression associated with a stressful and painful medical disorder.

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Heart failure patients benefit from dapagliflozin after TAVR procedure

Patients with heart failure who took dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at one year compared with patients who did not take the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Bentracimab reverses ticagrelor's antiplatelet effects during surgery and bleeding events

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's antiplatelet effects in patients undergoing urgent surgery or experiencing major bleeding, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

In patients experiencing excessive bleeding during cardiac surgery, a concentrated blood product containing proteins that help the blood clot was significantly more effective and caused fewer adverse effects than frozen plasma, the standard therapy, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

29 Mar 2025

Surgery News and Research

Clinical trial demonstrates safety of targeted treatment approach for deadly brain tumor in children

New CT-based score helps predict need for repeat sinus surgery

What’s lost: Trump whacks tiny agency that works to make the nation’s health care safer

Addressing low lung cancer screening rates through awareness and access

Macular thickness could predict postoperative delirium in older patients

Survey reveals high rate of NHS-related harm in Great Britain

How much will that surgery cost? 🤷 Hospital prices remain largely unhelpful.

High-fat diet linked to increased breast cancer metastasis risk

Scientists make breakthrough in understanding the causes of spina bifida

Hydrogel-based drug delivery offers hope for post-traumatic osteoarthritis

Gastric bypass proven most effective for severe obesity in landmark study

Scientists discover key genes for regenerating cells in the ear and eye

Queen Mary scientists invent a new way to repair osteochondral defects

New genetic discovery sheds light on PHTS-related vascular malformations

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

‘They won’t help me’: Sickest patients face insurance denials despite policy fixes

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Heart failure patients benefit from dapagliflozin after TAVR procedure

Bentracimab reverses ticagrelor's antiplatelet effects during surgery and bleeding events

Study finds 4F-PCC superior to frozen plasma in reducing bleeding after cardiac surgery

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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