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Ipsen reports positive initial results from Dysport phase III study in Adult Upper Limb spasticity

Ipsen today announced positive initial results from the double-blind phase III study of Dysport (abobotulinumtoxinA) in Adult Upper Limb spasticity. Regarding the primary endpoints, treatment with Dysport showed statistically significant response versus placebo in the improvement of muscle tone, as measured by the Modified Ashworth Scale.

17 Dec 2013

Poland's entry into EU may have led to consequence of increasing allergies in rural villages

Poland's entry into the EU may have had the surprising consequence of increasing allergies in rural villages, according to a new study. Surveys show that the prevalence of atopy, a predisposition towards allergic reactions, jumped from seven per cent to 20 per cent in villages in southwest Poland between 2003 and 2012.

17 Dec 2013

Alnylam initiates Phase II study with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated a pilot Phase II study with ALN-TTRsc, a subcutaneously delivered RNAi therapeutic targeting the transthyretin gene in development for the treatment of TTR-mediated amyloidosis.

17 Dec 2013

WSU researchers discover how Nipah virus employs burglary-ring-like teamwork to infiltrate human cell

A team of scientists from Washington State University has discovered how one of the planet's most deadly known viruses employs burglary-ring-like teamwork to infiltrate the human cell.

17 Dec 2013

Increased risk of complications to mother, newborn associated with early-term deliveries

Enduring the last few weeks of pregnancy can be physically and emotionally challenging for some women. The aches and pains, the swelling of the limbs and the anxiety of when labor may start are part of the natural gestation process, but they also can seem unbearable.

17 Dec 2013

Research finds reduced allergy risk among children raised with dogs from birth

Children's risk for developing allergies and asthma is reduced when they are exposed in early infancy to a dog in the household, and now researchers have discovered a reason why.

17 Dec 2013

Fat mass not linked to lung function in children with asthma

A study suggests that the relationship between body mass and lung function in children with asthma is more nuanced than previously thought.

16 Dec 2013

Interactive booklet boosts parents’ RTI confidence

An interactive booklet given to parents in primary care can help them to be more knowledgeable and feel more confident about when and when not to consult a doctor for their child’s respiratory tract infections.

16 Dec 2013

Aerogen wins Medical Technology Company award for its innovative solutions to healthcare providers

Aerogen, a medical device and drug delivery company has been honoured as the Medical Technology Company of the Year Award 2013. Aerogen's patented vibrating mesh technology turns liquid medication into a fine particle mist, gently and effectively delivering drugs to the lungs of critically ill patients.

16 Dec 2013

Health Canada approves Genzyme's Lemtrada for adults with relapsing remitting multiple sclerosis

Genzyme, a Sanofi company, announced today that Health Canada has approved Lemtrada (alemtuzumab) for the management of adult patients with relapsing remitting multiple sclerosis, with active disease defined by clinical and imaging features, who have had an inadequate response to interferon beta or other disease-modifying therapies.

13 Dec 2013

Brazilian study provides evidence to support effectiveness of Tecta in erosive GERD

Takeda Pharmaceuticals International GmbH announced today results showing pantoprazole magnesium 40 mg (Tecta) was as effective as esomeprazole 40 mg for achieving complete remission (defined as combined endoscopic healing and symptomatic relief) and the mucosal healing rate was high, whilst providing significantly higher symptom relief after 8 weeks.

13 Dec 2013

Cinnamon, nutmeg, marshmallows provide more than taste of holiday spice

Cinnamon, nutmeg and marshmallows provide more than a taste of holiday spice or a sugar rush. They are the ingredients for recipes for trendy risky games played by many to disasterous consequences.

13 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

Researchers at the Icahn School of Medicine at Mount Sinai reported that a virulent new strain of influenza - the virus that causes the flu - appears to retain its ability to cause serious disease in humans even after it develops resistance to antiviral medications. The finding was included in a study that was published today in the journal Nature Communications.

12 Dec 2013

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

GlaxoSmithKline plc announced today that a peer-reviewed study issued online by the New England Journal of Medicine has reported that GSK's FluLaval® Quadrivalent reduced flu cases among children ages 3-8 by 55.4% overall and lowered the risk of developing moderate-to-serious flu illness by 73.1%.

12 Dec 2013

Emergent BioSolutions enters into definitive agreement to acquire Cangene

Emergent BioSolutions Inc.announced that it has entered into a definitive agreement with Cangene Corporation (TSX: CNJ) under which Emergent will acquire all of the outstanding common shares of Cangene in an all-cash transaction valued at $3.24 per share on a fully diluted basis for an aggregate purchase price of $222 million.

12 Dec 2013

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

MedImmune, AstraZeneca’s global biologics research and development arm, and The Johns Hopkins University today announced they have entered into a five-year, $6.5 million research collaboration.

12 Dec 2013

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

AstraZeneca and Bristol-Myers Squibb Company (NYSE:BMY) today announced the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC) recommends the investigational medicine metreleptin for the treatment of pediatric and adult patients with generalized lipodystrophy (LD).

12 Dec 2013

New guidelines developed to manage heart failure in children with undiagnosed heart disease

12 Dec 2013

Celgene subsidiary presents REVLIMID study results on lymphoma at ASH annual meeting

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ:CELG) today announced that results from two studies of REVLIMID (lenalidomide) combinations in patients with diffuse large B-cell lymphoma (DLBCL) were presented at the American Society of Hematology annual meeting in New Orleans, La.

11 Dec 2013

Respiratory News and Research

Ipsen reports positive initial results from Dysport phase III study in Adult Upper Limb spasticity

Poland's entry into EU may have led to consequence of increasing allergies in rural villages

Alnylam initiates Phase II study with ALN-TTRsc for treatment of ATTR

WSU researchers discover how Nipah virus employs burglary-ring-like teamwork to infiltrate human cell

Increased risk of complications to mother, newborn associated with early-term deliveries

Research finds reduced allergy risk among children raised with dogs from birth

Fat mass not linked to lung function in children with asthma

Interactive booklet boosts parents’ RTI confidence

Aerogen wins Medical Technology Company award for its innovative solutions to healthcare providers

Health Canada approves Genzyme's Lemtrada for adults with relapsing remitting multiple sclerosis

Brazilian study provides evidence to support effectiveness of Tecta in erosive GERD

Cinnamon, nutmeg, marshmallows provide more than taste of holiday spice

New guidelines to manage heart failure in children

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

Emergent BioSolutions enters into definitive agreement to acquire Cangene

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

FDA Advisory Committee recommends metreleptin for treatment of generalized lipodystrophy

New guidelines developed to manage heart failure in children with undiagnosed heart disease

Celgene subsidiary presents REVLIMID study results on lymphoma at ASH annual meeting

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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