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Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

Pharmacyclics, Inc. today announced results of 40 clinical, non-clinical and pre-clinical presentations on ibrutinib (IMBRUVICA™) at the 55TH Annual meeting of the American Society of Hematology (ASH) held in New Orleans, Dec 7 - 10, 2013.

11 Dec 2013

AANMA partners with AAE and AAPA-AAI to build network focusing on allergy, asthma care

Allergy & Asthma Network Mothers of Asthmatics, a leading patient education organization, is partnering with the Association of Asthma Educators and the American Academy of Physician Assistants in Allergy, Asthma & Immunology as part of its endeavor to build the only multidisciplinary, patient-centered network of healthcare professionals focused on allergy and asthma care.

10 Dec 2013

Preparing for better management of Tamiflu-resistant influenza viruses

Researchers in Umeå and Uppsala have found that residues of the influenza drug Tamiflu in our environment can make the influenza virus in birds resistant. This can have serious consequences in the event of an influenza pandemic. With more than 14 million SEK from the Swedish Research Councils Formas and VR, the research team will now continue their studies with a focus on alternative antiviral drugs.

10 Dec 2013

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has presented new pre-clinical data with ALN-AT3, a subcutaneously administered RNAi therapeutic targeting antithrombin (AT) for the treatment of hemophilia and rare bleeding disorders (RBD), at the 55th Annual Meeting of the American Society of Hematology (ASH) held December 7 - 10, 2013 in New Orleans.

10 Dec 2013

Takeda presents clinical study results of oral proteasome inhibitor MLN9708 in multiple myeloma patients

Takeda Pharmaceutical Company Limited today announced final Phase 1 and preliminary Phase 2 results of a study combining oral investigational MLN9708 administered twice a week with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma.

10 Dec 2013

Private contractors who worked in conflict environments struggle from depression, PTSD

Private contractors who worked in Iraq, Afghanistan or other conflict environments over the past two years report suffering from post-traumatic stress disorder and depression more often than military personnel who served in recent conflicts, according to a new RAND Corporation study.

10 Dec 2013

Acetylon Pharmaceuticals presents positive interim data from two ricolinostat clinical trials at ASH 2013

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase inhibitors for enhanced therapeutic outcomes, today announced that positive interim clinical data from the two proof-of-concept clinical trials with selective HDAC6 inhibitor, ricolinostat (ACY-1215), were presented at the 55th Annual Meeting of the American Society of Hematology in New Orleans, LA.

9 Dec 2013

FDA advisory committee backs Takeda's vedolizumab for treatment of ulcerative colitis, Crohn's disease

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals U.S.A., Inc., today announced that a joint panel of members from the Gastrointestinal Drugs and Drug Safety and Risk Management Advisory Committees of the United States Food and Drug Administration voted to recommend approval of Takeda's vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis and Crohn's disease.

9 Dec 2013

Early lung infection exacerbates asthma risk in preterm birth children

A Swedish study of children admitted to hospital within the first year of life for lung infection has found that the increased risk this poses for later development of asthma is exacerbated by low gestational age.

9 Dec 2013

Atonomics reaches agreement to advance development of diagnostic test for lifestyle diseases

Atonomics announces today that it has entered into an agreement with Omron Healthcare, which will enable Atonomics to advance the development of the AtolyzerConsumer device for advanced diagnostic testing of lifestyle diseases in a consumer pharmacy setting. As part of the transaction Omron Healthcare is taking a minority equity stake in Atonomics.

9 Dec 2013

Taking probiotics during pregnancy has no effect on asthma rate amoung infants

Taking probiotics has health benefits but preventing childhood asthma isn't one of them, shows newly published research led by medical scientists at the University of Alberta.

9 Dec 2013

Janssen reports positive pivotal Phase 2 study data of siltuximab for Multicentric Castleman's Disease

Janssen Research & Development, LLC today announced positive results from a pivotal Phase 2 global registration study (MCD2001) suggesting siltuximab, an investigational compound, along with best supportive care, exhibited statistically significant efficacy and a tolerable safety profile compared with placebo and BSC in treating patients with the rare disorder Multicentric Castleman's Disease who are HIV-negative and human herpes virus 8-negative.

8 Dec 2013

Children with higher parental stress gain more weight

Parental stress is linked to weight gain in children, according to a new study from St. Michael's Hospital. The study found that children whose parents have high levels of stress have a Body Mass Index, or BMI, about 2 per cent higher than those whose parents have low levels of stress. Children with higher parental stress also gained weight at a 7 per cent higher rate during the study period than other children.

8 Dec 2013

ATS Labs offers testing of antimicrobial products for efficacy against H7N9 virus

ATS Labs announced today that they are pleased to offer testing of antimicrobial products for efficacy against avian influenza A (H7N9) virus. Avian influenza A (H7N9) virus, called H7N9 for short, has infected humans in China causing severe respiratory illness.

6 Dec 2013

Auxilium Pharmaceuticals' XIAFLEX gets FDA approval for treatment of Peyronie's disease

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, announced today that the U.S. Food and Drug Administration has approved XIAFLEX (collagenase clostridium histolyticum, or CCH), an in-office, biologic for the treatment of Peyronie's disease. XIAFLEX is the first and only FDA-approved treatment proven effective for PD in men with a palpable plaque and a curvature deformity of 30 degrees or greater at the start of therapy.

6 Dec 2013

Maternal weight issues spell wheezing trouble for children

High maternal weight and gestational weight gain are independently associated with an increased risk for wheezing in preschool age children, a Dutch study has found.

6 Dec 2013

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Sanford-Burnham scientists have identified the B and T Lymphocyte Attenuator (BTLA) inhibitory receptor as a key factor in limiting inflammatory responses, particularly in the skin. The study, published online today in Immunity, provides clarity on how T cells get fired up to protect against pathogens, and then cool down to restore immune homeostasis.

6 Dec 2013

Quadriplegics have heightened risk of central sleep apnea

There are over a million people with spinal cord injuries in the United States alone with an estimated 11,000 new cases every year. Furthermore, it is estimated that there are, at least, 100,000 veterans with SCI, making the VA the largest integrated health care system in the world for SCI care. But despite this large prevalence, researchers are still discovering all the various ways that SCI affect those with this condition beyond the obvious paralysis.

6 Dec 2013

Autumn-born children prone to asthma

Month of birth closely correlates with the prevalence of bronchial asthma, a major study of Taiwanese children has found.

5 Dec 2013

Alvotech to invests $250M in the development of biosimilar monoclonal antibodies

Alvotech, a powerful new player in the field of biopharmaceuticals, today announced plans to invest $250 million in the development and manufacturing of a portfolio of biosimilar monoclonal antibodies.

5 Dec 2013

Respiratory News and Research

Pharmacyclics presents ibrutinib trial data for B-cell malignancies at ASH meeting

AANMA partners with AAE and AAPA-AAI to build network focusing on allergy, asthma care

Preparing for better management of Tamiflu-resistant influenza viruses

Alnylam presents new pre-clinical data with ALN-AT3 for treatment of hemophilia and RBD

Takeda presents clinical study results of oral proteasome inhibitor MLN9708 in multiple myeloma patients

Private contractors who worked in conflict environments struggle from depression, PTSD

Acetylon Pharmaceuticals presents positive interim data from two ricolinostat clinical trials at ASH 2013

FDA advisory committee backs Takeda's vedolizumab for treatment of ulcerative colitis, Crohn's disease

Early lung infection exacerbates asthma risk in preterm birth children

Atonomics reaches agreement to advance development of diagnostic test for lifestyle diseases

Taking probiotics during pregnancy has no effect on asthma rate amoung infants

Janssen reports positive pivotal Phase 2 study data of siltuximab for Multicentric Castleman's Disease

Children with higher parental stress gain more weight

ATS Labs offers testing of antimicrobial products for efficacy against H7N9 virus

Auxilium Pharmaceuticals' XIAFLEX gets FDA approval for treatment of Peyronie's disease

Maternal weight issues spell wheezing trouble for children

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Quadriplegics have heightened risk of central sleep apnea

Autumn-born children prone to asthma

Alvotech to invests $250M in the development of biosimilar monoclonal antibodies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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