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NVP-BEZ235 inhibits growth of ovarian cancer cells, increases survival: Study

An experimental drug that blocks two points of a crucial cancer cell signaling pathway inhibits the growth of ovarian cancer cells and significantly increases survival in an ovarian cancer mouse model, a study at UCLA's Jonsson Comprehensive Cancer Center has found.

16 Apr 2011

Probiotic may reduce rate of recurrent urinary tract infections in women

Urinary tract infections are common in women, costing an estimated $2.5 billion per year to treat in 2000 in the United States alone. These infections frequently recur, affecting 2 to 3 percent of all women.

16 Apr 2011

Data of ImmunoCellular's lead dendritic cell cancer vaccine candidate for GBM presented at AAN meeting

ImmunoCellular Therapeutics, Ltd., announced that Surasak Phuphanich, MD, Principal Investigator of the Phase I clinical trial of ImmunoCellular's lead dendritic cell cancer vaccine candidate for glioblastoma multiforme presented safety and preliminary efficacy data yesterday at the American Academy of Neurology 63rd Annual Meeting.

16 Apr 2011

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

New results from the largest multicenter clinical trial for heart transplant patients will be released this week at the International Society for Heart & Lung Transplantation 31st Annual Meeting and Scientific Sessions in San Diego. Results show clinical benefit for the use of Everolimus in heart transplant patients.

16 Apr 2011

Complementary alternative medicine may improve quality of life in urban adolescents with asthma

A new study by researchers at the University of Cincinnati shows that urban adolescents with asthma may experience worse outcomes when not using spiritual coping and often use complementary and alternative medicine, or integrative medicine, like prayer or relaxation, to manage symptoms.

16 Apr 2011

Opexa's Tovaxin Phase IIb study data in MS presented at AAN meeting

Opexa Therapeutics, Inc., a company developing Tovaxin, a novel T-cell therapy for multiple sclerosis, today presented important efficacy data at the American Academy of Neurology 63rd Annual Meeting.

16 Apr 2011

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Pfizer Inc. announced today top-line results from the ORAL Scan Phase 3 study of tofacitinib, formerly known as tasocitinib, an investigational, novel, oral JAK inhibitor.

15 Apr 2011

Genentech receives FDA approval for Actemra to treat juvenile idiopathic arthritis

The U.S. Food and Drug Administration today approved Actemra, given alone or in combination with methotrexate, for the treatment of active systemic juvenile idiopathic arthritis in children ages 2 years and older.

15 Apr 2011

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.

15 Apr 2011

New JAMA issue focuses on infectious diseases and immunology

Several media outlets report on findings published in this week's issue of JAMA, which focuses on infectious diseases and immunology.

15 Apr 2011

Genzyme reports positive data from 5-year alemtuzumab Phase 2 study in MS

Genzyme Corp., a subsidiary of sanofi-aventis Group, today reported additional five-year patient data from its completed Phase 2 multiple sclerosis (MS) trial showing that nearly two-thirds of alemtuzumab treated patients remained free of clinically-active disease as much as four years after most patients received their last course of the investigational drug.

15 Apr 2011

Researchers develop Short-CGH method for preimplantation genetic screening

A Short Comparative Genomic Hybridisation method has been developed to carry out preimplantation genetic screening by analysing all chromosomes and transferring selected embryos to the recipient uterus in the same in vitro fertilisation cycle. This eliminates the need to freeze them.

15 Apr 2011

African genital herpes strains are more infectious than the U.S. virus

Strains of genital herpes in Africa are far more virulent than those in the United States, researchers at Harvard Medical School report, a striking insight into a common disease with important implications for preventing HIV transmission in a region staggered by the HIV/AIDS epidemic.

15 Apr 2011

Researchers temporarily turn off essential gene using RNAi technology

One way of discovering a gene's function is to switch it off and observe how the loss of its activity affects an organism. If a gene is essential for survival, however, then switching it off permanently will kill the organism before the gene's function can be determined. Researchers at Cold Spring Harbor Laboratory (CSHL) have overcome this problem by using RNA interference (RNAi) technology to temporarily turn off any essential gene in adult mice and then turn it back on before the change kills the animals.

15 Apr 2011

QRxPharma receives new U.S. Patent for MoxDuo IR in treatment of acute pain

QRxPharma Limited announced today that the United States Patent and Trademark Office issued the Company a new patent, U.S. Patent #7,923,453, which expires in 2029. This patent covers a proprietary dosing algorithm for converting patients from intravenous opioid administration to orally administered MoxDuo IR, thereby more effectively and safely managing acute pain following surgery.

15 Apr 2011

NRC, NCKU partner to develop cancer diagnostic and treatment technologies

A Taiwanese research team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at National Cheng Kung University has partnered with a research group led by Dr. Dennis Whitefield from National Research Council of Canada to develop innovative cancer diagnostic and treatment technologies.

15 Apr 2011

The Wistar Institute, Advaxis enter research collaboration

Advaxis, Inc., the live, attenuated Listeria monocytogenes vaccine company, has entered into a research collaboration with the laboratory of Ellen Puré, Ph.D., professor/associate vice president for Academic Affairs at The Wistar Institute.

15 Apr 2011

Cerapedics announces i-FACTOR biologic bone graft study results in PLIF spine surgery

Cerapedics, Inc., a medical device company focused on developing and commercializing novel osteobiologic products, announced the results of a prospective, randomized, controlled trial of its i-FACTOR biologic bone graft for patients undergoing posterior lumbar interbody fusion spine procedures.

12 Apr 2011

Teva presents new CNS products study data in RRMS, Parkinson's at AAN meeting

Teva Pharmaceutical Industries Ltd. today announced that several new studies further support the efficacy and safety of the company's innovative central nervous system products.

12 Apr 2011

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

A novel brain tumor vaccine clinical trial study demonstrates a longer survival time in patients with glioblastoma, according to findings being presented at the 79th Annual Scientific Meeting of the American Association of Neurological Surgeons in Denver.

12 Apr 2011

Efficacy News and Research

NVP-BEZ235 inhibits growth of ovarian cancer cells, increases survival: Study

Probiotic may reduce rate of recurrent urinary tract infections in women

Data of ImmunoCellular's lead dendritic cell cancer vaccine candidate for GBM presented at AAN meeting

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

Complementary alternative medicine may improve quality of life in urban adolescents with asthma

Opexa's Tovaxin Phase IIb study data in MS presented at AAN meeting

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Genentech receives FDA approval for Actemra to treat juvenile idiopathic arthritis

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

New JAMA issue focuses on infectious diseases and immunology

Genzyme reports positive data from 5-year alemtuzumab Phase 2 study in MS

Researchers develop Short-CGH method for preimplantation genetic screening

African genital herpes strains are more infectious than the U.S. virus

Researchers temporarily turn off essential gene using RNAi technology

QRxPharma receives new U.S. Patent for MoxDuo IR in treatment of acute pain

NRC, NCKU partner to develop cancer diagnostic and treatment technologies

The Wistar Institute, Advaxis enter research collaboration

Cerapedics announces i-FACTOR biologic bone graft study results in PLIF spine surgery

Teva presents new CNS products study data in RRMS, Parkinson's at AAN meeting

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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