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Ionophore use in farming drives global spread of antibiotic resistance genes, study finds

Researchers identified the widespread presence of the ionophore resistance genes narA and narB in over 2,400 bacterial isolates across 51 countries. These genes are often genetically linked to resistance against critically important human antibiotics, raising concerns over agricultural practices and global antimicrobial resistance.

30 Jun 2025

How 50,000 years of ancestry shaped India’s unique disease patterns

Scientists sequenced the genomes of 2,762 individuals across India, revealing the country’s unique ancestral makeup and a wealth of previously undocumented disease-related gene variants. The study highlights how ancient migrations, founder effects, and endogamy have shaped both diversity and disease risk in India.

29 Jun 2025

Discovery of a genetic dimmer switch controlling embryonic development

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that controls how genes are switched ‘on’ and ‘off’ during embryonic development.

27 Jun 2025

PIEZO2 ion channel plays critical role in the formation of coronary vessels and the heart

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in "Nature Cardiovascular Research."

27 Jun 2025

Reconstructing 50,000 thousand years of Indian ancestry using whole-genome data

India's population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets.

27 Jun 2025

Study maps HER2 mutations in lung cancer patients from Northeastern Brazil

A new research paper was published in Volume 16 of Oncotarget on June 17, 2025, titled "Molecular landscape of HER2-mutated non-small cell lung cancer in Northeastern Brazil: Clinical, histopathological, and genomic insights."

27 Jun 2025

New center in Copenhagen to pioneer the future of protein design

Proteins are the workhorses of biology. They perform virtually every important function in living organisms. They store, copy and protect our DNA, digest food to give us energy, and harness this energy to make our cells and muscles work.

27 Jun 2025

Soil bacterium offers clues for new bioactive compounds

A recent study by an interdisciplinary research team shows how a soil bacterium can become a source of inspiration in the search of new active substances.

27 Jun 2025

New technology brings antibiotic resistance surveillance to the field

Antibiotics are one of the greatest triumphs in the history of medical science - but these lifesaving tools have a dark side.

26 Jun 2025

Can your athletic past raise your risk for atrial fibrillation?

Elite retired rowers face a nearly threefold increased risk of atrial fibrillation compared to the general population, driven by a combination of long-term cardiac remodelling and underlying polygenic genetic susceptibility.

26 Jun 2025

Study reveals how FOXA1 mutations drive prostate cancer and therapy resistance

A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene-commonly altered in prostate cancer-drive tumor initiation formation and therapeutic resistance.

26 Jun 2025

Can saffron treat Alzheimer’s and depression?

Saffron shows promise as a natural treatment for depression and cognitive decline, performing as well as standard drugs in clinical trials. However, more rigorous studies are needed before saffron can be recommended in mainstream psychiatric and dementia care.

26 Jun 2025

Largest Indian genome study reveals 50,000 years of genetic history

With around 5,000 different ethno-linguistic and religious groups, India is one of the most culturally and genetically diverse countries in the world.

26 Jun 2025

Fire smoke exposure found to alter immune system at the cellular level

Exposure to fire smoke-which can be composed of particulate matter, gases, materials from buildings such as perfluoroalkyl and polyfluoroalkyl substances (PFAS), toxic metals, and carcinogenic compounds-may alter the immune system on a cellular level, according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

26 Jun 2025

New insights into programmed cell death could offer relief for inflammatory bowel disease

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease.

26 Jun 2025

Harnessing saliva for precision medicine and early disease diagnosis

A research team led by the University of the Basque Country (Euskal Herriko Unibertsitatea, EHU) has identified hundreds of molecular markers in saliva that could reveal the risk of a person developing major diseases such as cancer, cardiovascular diseases, diabetes and neurodegenerative diseases.

26 Jun 2025

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.

26 Jun 2025

Ribonucleases revealed as key players in Mendelian disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Targeting the tumor microenvironment to improve osteosarcoma outcomes

The complex tumor microenvironment (TME) in osteosarcoma is emerging as a critical factor in disease progression and treatment resistance.

26 Jun 2025

Missing gut bacteria in US babies triples allergy and eczema risk

US infants lacking Bifidobacterium in their gut microbiome face significant changes in microbial composition, metabolic function, and immune-related health risks. This large, nationally representative study links early-life Bifidobacterium deficits to a three-fold increase in eczema, allergy, or asthma by age two.

25 Jun 2025