Anaphylaxis News and Research

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Anaphylaxis is an acute multi-system severe type I hypersensitivity reaction. Due in part to the variety of definitions, between 1% and 15% of the population of the United States can be considered "at risk" for having an anaphylactic reaction if they are exposed to one or more allergens. Of those people who actually experience anaphylaxis, up to 1% may die as a result.

Unusual allergy triggers cause anaphylaxis in children and teenagers

When people think about anaphylaxis, peanuts, shellfish, or even bee sting often come to mind. Three medically challenging cases presented at the American College of Allergy, Asthma and Immunology (ACAAI) 2026 Annual Scientific Meeting show that severe allergic reactions can come from far less obvious places: a fish ingredient hidden in an energy drink, a natural hair oil and a popular children's sensory toy.

12 Nov 2026

Biologic drug offers promising protection against alpha-gal syndrome

The summer of 2026 was a particularly bad season for ticks. And with it came a rising number of cases of alpha-gal syndrome (AGS) thanks to bites from the Lone Star Tick.

12 Nov 2026

Stocking epinephrine in schools protects students and eases family financial burdens

For school kids with severe food allergies, having epinephrine on hand at school can mean the difference between a scary moment and a life-threatening one.

12 Nov 2026

Supervised food challenges clear many infants of suspected peanut allergy

A world-first national program has discovered more than a third of babies thought to have a peanut allergy could safely have the diagnosis removed. And the findings are changing how Australia's healthcare system approaches infant food allergies.

4 Nov 2026

Before the first bite: A missing gut protein may set the stage for peanut allergy

For most people, a peanut butter sandwich poses no threat. But for the roughly 1.6 million children in the United States with peanut allergy, exposure can trigger a life-threatening reaction.

6 Oct 2026

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

A large Australian randomized trial of 2,137 pregnant women tested whether substantially increasing egg and peanut consumption during pregnancy and breastfeeding could prevent food allergy in infants with a strong family history of allergic disease. Higher maternal intake did not significantly reduce IgE-mediated egg or peanut allergy at 1 year, although the lower-than-expected allergy rate limited statistical power and the results could not exclude a clinically important benefit.

17 Sep 2026

Orexo announces FDA acceptance of Investigational New Drug (IND) application for OX640 for the treatment of anaphylaxis

Orexo AB (publ.) today announces that the U.S. Food and Drug Administration (FDA) has accepted its Investigational New Drug (IND) application for OX640, a nasally administered powder formulation of epinephrine intended for the emergency treatment of anaphylaxis.

15 Sep 2026

Martha's Vineyard Hospital launches study to better understand alpha-gal syndrome

Martha's Vineyard Hospital, a member of Mass General Brigham, has begun recruiting participants for a research study designed to better understand alpha-gal syndrome (AGS), a potentially serious allergic condition associated with lone star tick exposure.

25 Aug 2026

Tick-borne alpha-gal syndrome poses potential risks during blood transfusions

A new multi-institute study led by researchers at Dartmouth Health and Geisel School of Medicine at Dartmouth suggests that alpha-gal syndrome, the tick-borne disease that can result in a chronic allergy to meat and animal byproducts, also may complicate certain patients' ability to safely receive a blood plasma or platelet transfusion.

24 Aug 2026

Researchers uncover mechanism linking skin inflammation to body-wide allergies

Our bodies experience allergic reactions when the immune system mistakenly overreacts to harmless substances, known as allergens, such as pollen, dust, or certain foods.

6 Aug 2026

Microbiome-based therapy may increase peanut allergy tolerance in adults

Some 33 million Americans have severe food allergies. Now, researchers at Boston Children's Hospital may have found a promising solution.

5 Aug 2026

Mouse study links leaky gut to severe food allergies

A "leaky gut" might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology.

31 Jul 2026

Omalizumab beats multiallergen oral immunotherapy in multifood allergy trial

Omalizumab demonstrates higher treatment success for multifood allergies compared to oral immunotherapy, with fewer adverse events impacting patient retention.

30 Jul 2026

Review highlights strong safety and effectiveness of mRNA vaccines

A comprehensive new review published in The Lancet affirms that currently approved mRNA vaccines are safe and highly effective at preventing infectious diseases, including COVID-19.

30 Jun 2026

Review explores diagnosis and management of perioperative anaphylaxis during anesthesia

Perioperative anaphylaxis is a rare, life‑threatening condition during anesthesia. The unique setting – multiple drugs, patient draping, and altered physiology – causes higher mortality than anaphylaxis elsewhere.

29 May 2026

Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial

A Swedish randomized trial found that slow up-dosing peanut oral immunotherapy with a low maintenance dose helped 82% of preschool children achieve sustained peanut tolerance after three years. The approach proved safer than conventional protocols, with severe reactions uncommon and strong family adherence throughout treatment.

10 May 2026

Anaphylaxis News and Research

Further Reading

Unusual allergy triggers cause anaphylaxis in children and teenagers

Biologic drug offers promising protection against alpha-gal syndrome

Stocking epinephrine in schools protects students and eases family financial burdens

Supervised food challenges clear many infants of suspected peanut allergy

Before the first bite: A missing gut protein may set the stage for peanut allergy

Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test

Orexo announces FDA acceptance of Investigational New Drug (IND) application for OX640 for the treatment of anaphylaxis

Martha's Vineyard Hospital launches study to better understand alpha-gal syndrome

Tick-borne alpha-gal syndrome poses potential risks during blood transfusions

Researchers uncover mechanism linking skin inflammation to body-wide allergies

Microbiome-based therapy may increase peanut allergy tolerance in adults

Mouse study links leaky gut to severe food allergies

Omalizumab beats multiallergen oral immunotherapy in multifood allergy trial

Review highlights strong safety and effectiveness of mRNA vaccines

Review explores diagnosis and management of perioperative anaphylaxis during anesthesia

Slow and steady wins: Low-dose peanut immunotherapy safely desensitizes 82% of preschoolers in landmark trial

Delayed adrenaline use linked to fatal childhood food anaphylaxis

When rice-based formula is the right choice for cow’s milk allergy

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Gut bacteria may explain differences in peanut allergy reactions

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