Aorta News and Research

RSS

Study maps key regions driving inflammation in aging hearts

Scientists have long known that aging drives inflammation in the heart, but exactly how those changes are distributed throughout the organ has remained unclear.

6 Nov 2026

Myeloid immune cells play key roles in aortic health and disease

The aorta is often viewed primarily as the body's largest blood vessel-a durable conduit that delivers oxygen-rich blood from the heart to every organ.

30 Oct 2026

New surgical technique enlarges aortic roots for larger valve implants

When replacing the aortic valve, a small aortic root can limit the size of the prosthetic valve that can be implanted.

16 Oct 2026

Biomechanical strain keeps heart valves strong for decades

Collagen plays a critical role in keeping heart valves strong, but the heart is surrounded by enzymes designed to break down collagen.

14 Oct 2026

Cornell researchers document first case of Marfan syndrome in cats

Researchers at Cornell University have documented the first molecular characterization of Marfan syndrome in domestic cats in a paper in Scientific Reports.

25 Sep 2026

Menopause may not drive rising pulse pressure and midlife aortic stiffness in women

Contradicting conventional wisdom, menopause may not be the driving force behind an increase in aortic stiffness in women after midlife, according to new, independent research published today in Hypertension, a peer-reviewed scientific journal published by the American Heart Association journal.

15 Sep 2026

Physics-informed AI framework improves aortic aneurysm stress prediction

Ascending thoracic aortic aneurysms often progress silently, but once dissection or rupture occurs, they can cause severe mortality before hospital arrival or during admission.

4 Sep 2026

Deep-learning tissue clocks reveal how organs age and leave disease-linked signals in blood

Deep learning applied to more than 25,000 histopathology slides revealed tissue-specific structural signatures of biological aging that tracked telomere attrition, pathology, comorbidity, and molecular changes more closely than chronological age alone.

18 Aug 2026

Accumulation of somatic mutations drives vascular damage in people with progeria

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging.

31 Jul 2026

Two heart nerve cell types sustain cardiac stability in mice

Researchers identified two major intrinsic cardiac neuron populations in mice: Npy-positive neurons regulate parasympathetic heart rate control and support coronary perfusion, while Ddah1-positive neurons help maintain electrical stability during extreme stress. Removing Npy-positive neurons caused fatal cardiac failure, whereas loss of Ddah1-positive neurons increased susceptibility to malignant arrhythmias and sudden cardiac arrest under stress.

23 Jul 2026

Study: Aortic dissection survivors can participate in moderate‑intensity exercise at home

A multicenter clinical trial led by UTHealth Houston has found that survivors of aortic dissection can participate in moderate‑intensity exercise at home without increasing the risk of recurrent aortic events.

9 Jul 2026

Landmark study confirms long-term durability of Ross procedure for aortic valve replacement

The Ross procedure, a highly specialized option for aortic valve replacement, is associated with significant long-term durability and excellent outcomes in a wide range of adult patients with aortic valve disease.

23 Jun 2026

Microbially modified bile acids influence sleep apnea outcomes

Studies in mice reveal a new target for potentially treating and preventing life-threatening cardiovascular complications in the millions of patients with sleep apnea worldwide.

7 Jun 2026

Early paracetamol may speed up heart vessel closure in preterm babies

Early administration of paracetamol may accelerate closure of the patent ductus arteriosus in extremely preterm babies, according to a new study.

3 Jun 2026

New PET imaging tracks tumor progression and cardiac inflammation during cancer therapy

A novel PET imaging approach enables simultaneous visualization of tumor progression and cardiac inflammatory responses during cancer treatment.

1 Jun 2026

Active brown fat may protect heart health in obese individuals

People with obesity face a significantly increased risk of atherosclerosis, and consequently heart attack and stroke.

4 May 2026

Genetic research identifies rare DNA changes causing common heart valve defect

New clues from genetic research may help explain what causes the most common heart defect present at birth.

24 Apr 2026

Common osteoporosis drugs could slow or halt aneurysm progression

Aortic aneurysms are characterized by abnormal enlargement of the aorta, the primary artery responsible for carrying blood from the heart. Rupture often leads to sudden death, and currently, no effective drug therapies are available to halt disease progression.

14 Apr 2026

Targeted therapy treats mixed histiocytosis following multiple skull relapses

Mixed histiocytosis (Langerhans cell histiocytosis [LCH] / Erdheim-Chester disease [ECD]) developing after treatment for initial skull LCH is not well recognized.

13 Apr 2026

Trial shows mavacamten benefits adolescents with obstructive heart condition

Adolescent patients with obstructive hypertrophic cardiomyopathy (HCM) who received the drug mavacamten saw a significant improvement in left ventricular outflow tract (LVOT) gradient, a measure of blood flow obstruction in the heart, compared with those who received a placebo, according to a small study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026