Cell Adhesion News and Research

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Disrupted circadian rhythms may influence tumor immunity and cancer spread

Epidemiological studies link light at night (LAN), shift work, chronic jet lag (CJL), and core clock gene mutations to higher cancer risk and aggressive spread, especially in breast and colorectal cancer.

8 Oct 2026

Global scientific collaboration brings hope to lobular breast cancer patients

Every October, Breast Cancer Awareness Month brings people around the world together under the pink ribbon to raise awareness, encourage early detection, support patients and fund research.

6 Oct 2026

Retinal immune cell gateway may unlock targeted uveitis treatments

As part of an effort to understand the molecules and mechanisms that regulate transendothelial migration in different vascular beds of the body, researchers focused on the blood vessels of the retina, part of the blood-brain barrier.

8 Sep 2026

Tea, berries and dark chocolate featured in a diet linked to lower Parkinson’s risk

A prospective UK Biobank study of 123,655 adults found that a dietary pattern richer in flavonoid-containing foods was modestly associated with a lower incidence of hospital-recorded Parkinson’s disease. The association was strongest among those with the highest flavonoid diet scores, while exploratory proteomic and transcriptomic analyses pointed to possible neuroimmune and cell-adhesion pathways but did not establish causality or mechanism.

26 Aug 2026

Antibodies for visualizing cell identity and tumor architecture

Whether you are characterizing cell state transitions, assessing organelle integrity, or building a multiplex immunofluorescence (IF) assay, you need reliable structural markers for your imaging.

From Antibodies Incorporated 21 Aug 2026

Expanded DepMap reveals new cancer vulnerabilities through 3D tumor models

For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies - the genetic changes some cancers need to thrive that can potentially be targeted by new cancer drugs.

5 Aug 2026

Cell junction proteins regulate stem cell signaling and tissue homeostasis

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.

28 Jul 2026

Excess tubulin disrupts tissue organization and cell survival

A UNIGE study shows that even a slight overproduction of tubulin, a protein essential for cell structure, is enough to disrupt tissue organization, highlighting the need for tight regulation of protein levels.

22 Jul 2026

Researchers identify new genetic pathway driving epilepsy and seizures

Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about 50 % of individuals with the condition

16 Jul 2026

Genetic research links KDF1 mutation to impaired dental epithelial organization

Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay. However, enamel cannot regenerate once damaged. Inherited disorders, such as amelogenesis imperfecta, disrupt enamel formation during development, leaving affected individuals with fragile, discolored, and decay-prone teeth.

30 Jun 2026

Exercise, not liraglutide alone, drives vascular gains after obesity-related weight loss

A prespecified secondary analysis of the S-LiTE trial found that regular exercise reduced carotid artery wall thickness and circulating levels of inflammatory cytokines in adults with obesity who had already achieved substantial diet-induced weight loss. Liraglutide alone did not significantly improve these vascular or inflammatory markers, while exercise plus liraglutide also improved endothelial function biomarkers.

25 Jun 2026

Scientists find a universal gut microbiome pattern linked to colorectal cancer

Researchers analyzed 6,779 stool microbiome profiles and 906 tissue samples to identify a colorectal cancer microbial signature that remained consistent across age groups, populations, and sequencing methods. The signature aligned with tumor-resident microbes, showed weaker detection for adenomas, and was inversely associated with dietary fiber intake.

25 Jun 2026

Tissue rigidity actively regulates cell polarity and embryonic development

Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organise and reorganise themselves following incredibly precise patterns, while remaining flexible and robust.

2 Jun 2026

New peptide triggers domino effect to suppress bladder cancer

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin-plectin-vimentin/ITGβ4 axis (referred to as the "cytoskeletal domino effect").

25 May 2026

New imaging agent shows promise for non-invasive endometriosis diagnosis

The Nuffield Department of Women's & Reproductive Health at the University of Oxford, together with Serac Healthcare Limited announces the publication of Phase 2 data in The Lancet Obstetrics and Gynaecology.

29 Apr 2026

Study aims to understand molecular origins of CTNNB1 neurodevelopmental syndrome

On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare disease caused by mutations in the beta-catenin protein.

27 Feb 2026

Defective ASTN1 gene linked to developmental delay and neurological disorders

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development.

10 Feb 2026

Sub-terahertz biosensors enable label-free cancer cell identification

Early detection and accurate typing of cancer are critical for improving patient survival rates. While traditional pathology remains the gold standard, it often requires complex sample processing and chemical staining.

4 Feb 2026

Study shows DHPS enzyme controls macrophage maturation across multiple organs

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

21 Jan 2026

New antibody mechanisms disrupt bacterial adhesion in urinary tract infections

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

7 Jan 2026