Colonoscopy News and Research

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Colonoscopy is examination of the inside of the colon using a colonoscope, inserted into the rectum. A colonoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue to be checked under a microscope for signs of disease.

New study tracks global colorectal cancer risk across 185 nations

Colorectal cancer has long been recognized as a major global health threat, but its burden is far from evenly distributed. Incidence and mortality rates vary dramatically across countries, and these differences are closely tied to socioeconomic development, dietary transitions, and the adoption of screening programs.

26 Aug 2026

Scientists found a distinct gut microbiome pattern in people with symptomatic diverticular disease

A multicenter Japanese study found that symptomatic uncomplicated diverticular disease (SUDD) was associated with reduced gut microbial diversity, increased abundance of the Ruminococcus gnavus group, and depletion of Coprococcus and other butyrate-producing bacteria. Predictive microbiome analysis also identified enrichment of pathways linked to exopolysaccharide biosynthesis and the cell cycle, although the observational design means these associations cannot establish causality.

25 Aug 2026

Only 15% of eligible American adults discuss lung cancer screening with their doctors

Lung cancer screenings can save lives by detecting cancer in its early stages, but only 15% of eligible American adults have discussed the screening with their doctors, according to data analysis performed by University of Cincinnati Cancer Center researchers.

21 Aug 2026

Active screening cuts colorectal cancer death risk drastically

People who take part in screening for colorectal cancer may have as much as 43 per cent lower risk of dying from the disease, according to new estimates published in JAMA Network Open by researchers at Karolinska Institutet and Umeå University in Sweden.

20 Aug 2026

New study highlights noninvasive biomarkers for colorectal cancer detection

Emerging discoveries in liquid biomarker research promise to transform early detection, diagnosis, and treatment monitoring of colorectal cancer (CRC), according to a new study, offering less invasive alternatives to traditional methods that often require surgical interventions or tissue biopsies.

6 Jul 2026

AGA experts highlight benefits and limits of colorectal cancer screening tests

As new colorectal cancer screening guidance draws attention to the growing number of testing options, the American Gastroenterological Association urges patients and primary care providers to understand how those options compare.

17 Jun 2026

New manufacturing platform produces targeted mixtures of beneficial gut bacteria

Researchers at the Icahn School of Medicine at Mount Sinai have developed a new manufacturing platform for producing targeted mixtures of beneficial gut bacteria, an approach that could help expand access to microbiome-based therapies for patients with recurrent Clostridioides difficile (C. difficile) infection.

3 Jun 2026

Gut changes linger years after polyp removal and may signal colorectal cancer risk

Researchers found that women who had undergone colorectal adenoma resection still showed gut microbiome and fecal metabolome alterations an average of about 12 years later. These persistent changes partly resembled colorectal cancer-associated patterns, suggesting that the host-microbiome axis may remain altered along the adenoma-cancer continuum.

28 May 2026

New colorectal cancer screening guidelines emphasize advanced stool tests

With colorectal cancer a growing concern among younger people, the American Cancer Society has endorsed two new types of stool tests to encourage people to get screened while also recommending a limited role for new blood tests many patients find appealing.

27 May 2026

FIT intervention boosts colorectal cancer screening across racial/ethnic groups

Background: Racially and ethnically minoritized patients are underscreened for colorectal cancer, resulting in racial/ethnic disparities.

26 May 2026

Mailed DNA-based test for colorectal cancer screening

The use of mailed FIT-DNA kits in community health centers significantly increases colorectal cancer screening, though follow-up colonoscopy rates remain low.

30 Apr 2026

Newer mail-in stool tests increase colorectal cancer screening completion rates

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States and disproportionally impacts people who receive care in under-resourced settings.

27 Apr 2026

Trial shows durable response with preoperative immunotherapy in bowel cancer

Patients with a specific type of bowel cancer who were treated with a short course of immunotherapy before surgery instead of post-op chemotherapy have remained cancer-free after almost three years of follow-up, according to new results from the NEOPRISM-CRC clinical trial led by a team from UCL and UCLH.

20 Apr 2026