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$Refractory lichen planus-like lesions reveal underlying systemic T-cell lymphoma$

Refractory lichen planus-like lesions reveal underlying systemic T-cell lymphoma

A 61-year-old man had a 2-year history of painful mucosal lesions and pruritic violaceous plaques on the trunk and extremities.

6 Nov 2026

Researchers develop method to generate billions of cDC1 immune cells

Conventional type 1 dendritic cells, known as cDC1 cells, are immune cells that help initiate responses against intracellular pathogens and tumors.

4 Nov 2026

Researchers uncover how astrovirus spreads without destroying gut cells

Among the various viruses that sicken your gut, some at least leave behind a tiny path of cellular destruction as they replicate, implicating the guilty pathogen.

3 Nov 2026

Curiox Biosystems strengthens commercial leadership to expand adoption of centrifuge-free sample preparation

Curiox Biosystems Inc (Curiox), a provider of centrifuge-free (C-FREE™) sample preparation technologies for reproducible, automated flow cytometry workflows, today announced the expansion of its senior commercial team and the formation of a Strategic Advisory Board (SAB).

From Curiox Biosystems 30 Oct 2026

Amyloid fibers help sperm deliver RNA to mouse embryos

Researchers identified RNA-associated amyloid fibrils in human seminal fluid and demonstrated that synthetic PAP fibrils could enter mammalian sperm. In mouse IVF experiments, these fibrils helped sperm deliver RNA to embryos, where the detected reporter-protein signal was at least tenfold higher than without fibril exposure.

27 Oct 2026

Six-gene score could improve survival predictions for acute myeloid leukemia

The activity of six different genes can help determine patient survival of acute myeloid leukemia (AML), according to a study published today in Science Advances.

23 Oct 2026

Semaglutide and teduglutide reduce immune-driven gut injury in mice

Researchers found that gut-derived GLP-1 and GLP-2 signaling helped protect mice against T cell-induced intestinal injury, with GLP-1R primarily regulating inflammation and GLP-2R supporting intestinal repair. Semaglutide and teduglutide, administered separately or together, reduced acute intestinal damage in mice lacking intestinal proglucagon, suggesting potential avenues for investigating treatments for immune-mediated gut injury.

21 Oct 2026

Scientists discover a novel strategy to unmask cancer cells in high-risk neuroblastoma

High-risk neuroblastoma is one of the most aggressive forms of solid tumors affecting children, originating in the nervous system.

6 Oct 2026

SGLT2 inhibitors reduce inflammatory cells linked to heart disease

For the first time in a human trial, a class of drugs known as sodium-glucose cotransporter-2 (SGLT2) inhibitors, already known for their weight loss and glucose lowering benefits, has been shown to also reduce inflammatory cells in the blood known to cause cardiovascular disease.

6 Oct 2026

New BCR analysis method tracks immune recovery after stem cell transplantation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Could the gut be priming the body for a more severe stroke?

Gut bacteria may prime immune cells to worsen stroke damage

2 Oct 2026

Two-molecule blood test accurately identifies infections in febrile infants

A test that compares the levels of two molecules in the blood is able to accurately distinguish between bacterial and viral infections in newborn babies with fever in a small study presented at the European Emergency Medicine Congress today (Sunday).

27 Sep 2026

Kansas researchers secure NIH funding to fight antibiotic resistance

As antibiotic resistance makes everyday infections tougher to treat and emerging pathogens drive challenging infectious-disease outbreaks, researchers in Kansas from multiple disciplines and institutions are teaming up to target pathogens and overcome antibiotic resistance.

25 Sep 2026

Celastrol reduces cholestatic liver injury by inhibiting specific protein

Cholestasis occurs when bile formation, secretion, or flow is impaired, causing toxic bile acids to accumulate and trigger inflammation and liver-cell damage.

17 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Study shows mRNA vaccines trigger more diverse flu antibody responses

Influenza remains a major global health challenge as continual antigenic drift can limit the breadth and durability of vaccine-induced antibody responses, requiring frequent vaccine updates.

11 Sep 2026

Refined starch activates immune pathways after low-carb weight loss

After substantial weight loss on a very-low-carbohydrate diet, participants who switched to a diet rich in refined starch showed greater activation of circulating immune and metabolic pathways than those who continued the low-carbohydrate diet or consumed a high-carbohydrate diet rich in added sugar. Mouse experiments suggested that activation of the complement immune pathway may help explain the inflammatory response associated with starch intake.

10 Sep 2026

Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

In mice, intestinal infections reshaped dural CD4+ T-cell populations and seeded the brain’s outer meningeal border with antigen-specific memory cells that persisted for months and mounted rapid recall responses to bloodborne antigens. Oral priming was associated with reduced Salmonella spread to the brain and modest cross-protection in an engineered shared-antigen Candida model, although the researchers could not definitively prove that dural CD4+ T cells alone caused the protection.

9 Sep 2026

New laser-fabricated plasmonic chip accurately identifies and sorts cancer cells

Novel laser-fabricated plasmonic chip combines 185 nm Raman resolution and deep learning to identify and sort cancer cells with 96.2% accuracy.

9 Sep 2026

Retinal immune cell gateway may unlock targeted uveitis treatments

As part of an effort to understand the molecules and mechanisms that regulate transendothelial migration in different vascular beds of the body, researchers focused on the blood vessels of the retina, part of the blood-brain barrier.

8 Sep 2026