Cytoskeleton News and Research

RSS

Antibodies for visualizing cell identity and tumor architecture

Whether you are characterizing cell state transitions, assessing organelle integrity, or building a multiplex immunofluorescence (IF) assay, you need reliable structural markers for your imaging.

From Antibodies Incorporated 21 Aug 2026

Basel researchers challenge decades of belief about coronin proteins

Scientific progress comes not only from discovering something entirely new, but also from taking a fresh look at long-held assumptions.

18 Aug 2026

Expanded DepMap reveals new cancer vulnerabilities through 3D tumor models

For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies - the genetic changes some cancers need to thrive that can potentially be targeted by new cancer drugs.

5 Aug 2026

Artificial cells offer new insights into living cell behavior

Using simple artificial cells, a research group led by Makito Miyazaki of the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have uncovered fundamental physical principles that govern how living cells change their shape.

5 Aug 2026

Scientists uncover how muscle actin filaments grow and renew themselves

Biophysicists unraveled a mystery of how muscles form at the molecular level and how they maintain their function.

29 Jul 2026

Dormant melanocytes found in vitiligo offer hope for future repigmentation therapies

Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease.

23 Jul 2026

Excess tubulin disrupts tissue organization and cell survival

A UNIGE study shows that even a slight overproduction of tubulin, a protein essential for cell structure, is enough to disrupt tissue organization, highlighting the need for tight regulation of protein levels.

22 Jul 2026

Researchers identify new genetic pathway driving epilepsy and seizures

Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about 50 % of individuals with the condition

16 Jul 2026

Review highlights macrophages as key drivers of chronic transplant rejection

A comprehensive review led by Professors Malgorzata Kloc and Xian Chang Li at the Immunobiology and Transplant Science Center of Houston Methodist Hospital in the United States was published in Volume 2, article number 29 of the journal Immunity & Inflammation on June 30, 2026.

9 Jul 2026

Discovery provides key insights into cellular mechanisms underlying female fertility

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these follicles, the oocyte is surrounded by granulosa cells that supply nutrients, signaling molecules, and structural support essential for egg development.

2 Jul 2026

Cytoskeletal proteins in the cell nucleus influence brain development

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

Study identifies new therapeutic candidate for KRAS-driven pancreatic cancer

A new research paper was published in Volume 17 of Oncotarget on June 3, 2026, titled "The anticancer effects of PCAIs in pancreatic cancer cells involve MAPK and PI3K/AKT pathways hyperactivation."

8 Jun 2026

Study explains how environmental acidity destabilizes internal cellular traffic

A new scientific study led by the Universidad Carlos III de Madrid (UC3M) describes the mechano-chemical mechanism by which the acidity of the cellular environment destabilizes microtubules, the "avenues" that organize internal cellular traffic.

26 May 2026

New peptide triggers domino effect to suppress bladder cancer

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin-plectin-vimentin/ITGβ4 axis (referred to as the "cytoskeletal domino effect").

25 May 2026

ISTA researchers prove keratin is indispensable for coherent cell migration

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

22 May 2026

Scientists uncover cellular mechanism behind rare childhood brain disorders

Thousands of times per year, a family's moment of joy turns to unexpected grief. A seemingly healthy infant stops smiling or making eye contact.

8 May 2026

Cells filter physical forces based on duration to detect disease

Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.

29 Apr 2026

Microtubules unveiled as active enzyme regulators

Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling role. The findings, published in Science Advances, demonstrate that microtubules are in fact regulators of enzymatic reactions through reshaping the geometry of the enzyme's substrate proteins attached to them and controlling when key events occur to conduct cell division.

26 Mar 2026

Imaris 11 transforms image analysis with automated workflows and reproducible research tools

Discover how Imaris 11 streamlines image analysis with automated workflows, reproducibility tools, and powerful batch processing.

From Oxford Instruments - Life Sciences 13 Mar 2026

Understanding PIEZO2 mutations and sensory disorders

Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into an electrical signal that the brain can interpret as touch. While scientists have long known that a protein called PIEZO2 acts as a key sensor for touch, it remained unclear why PIEZO2 is specialized for the localized mechanical forces experienced by sensory neurons, whereas its close relative PIEZO1 responds to broader mechanical stresses such as those generated when cells stretch, as occurs in blood vessels.

9 Mar 2026