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Blocking complement factor B halts pancreatic cancer growth

Researchers have identified a promising new target in the treatment of pancreatic cancer. A new study in The American Journal of Pathology, published by Elsevier, demonstrates that blocking complement factor B (CFB), a pivotal enzyme in the alternative complement pathway, halts cancer growth and alters the tumor microenvironment.

9 Nov 2026

Blood biomarker tracks nerve damage from oxaliplatin-containing adjuvant chemotherapy

Oxaliplatin can cause numbness, tingling, and pain in the hands and feet, with consequences for mobility, work, and quality of life.

9 Nov 2026

New monoclonal antibody therapy significantly lowers patient triglyceride levels

A phase 2b clinical trial led by Mass General Brigham Heart and Vascular Institute researchers shows that a monoclonal antibody therapy called MAR001 can significantly reduce triglyceride levels within 12 weeks for patients with high triglyceride levels.

9 Nov 2026

Could a daily supplement keep blood vessels healthier as we age?

The study highlights a multi-compound nutritional supplement's potential to improve blood vessel function and lower blood pressure, aiding vascular health.

9 Nov 2026

Vulnerable DNA sites make cancer cells sensitive to PARP inhibitors

A small subset of vulnerable DNA sites can make cancer cells highly sensitive to targeted drugs called PARP inhibitors, a new study shows.

5 Nov 2026

Compound YZG-331 leverages gut microbiota to improve sleep in mouse models of insomnia

This new article publication from Acta Pharmaceutica Sinica B discusses how interactions between the investigational compound YZG-331 and the gut microbiota contribute to its sleep-promoting effects in mouse models of insomnia.

5 Nov 2026

Modern lifestyles may be changing our gut bacteria in unexpected ways

A global study of 1,015 adults across 12 countries found that industrialized lifestyles were associated with lower gut bacterial diversity, reduced microbial community stability, and increased markers of intestinal stress and immune activity. The researchers also found that a microbiome-based health index developed using industrialized populations performed poorly in less-industrialized communities, raising concerns about its applicability across diverse populations.

4 Nov 2026

New nanovesicle therapy shows promise for treating alcohol-related liver disease

Alcohol-related liver disease (ALD) is characterized by hepatocellular injury, oxidative stress, inflammation, and extracellular matrix remodeling, yet effective therapies remain limited.

4 Nov 2026

Genetic variant tied to liver injury from blood pressure drugs

This new article publication from Acta Pharmaceutica Sinica B discusses the clinical features and genetic associations of rare liver injury caused by antihypertensive medications.

4 Nov 2026

Study reveals how breast milk sugar may help protect infants against jaundice

A new study by researchers at the University of California San Diego School of Medicine sheds light on the role of breast milk in supporting intestinal development and preventing hyperbilirubinemia, a condition in which bilirubin, a waste product from broken-down red blood cells, builds up in the blood and causes yellowing of the skin and eyes known as jaundice.

3 Nov 2026

DHA improves autism-like behaviors in a preclinical rat study

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition marked by social and communication difficulties and repetitive behaviors.

3 Nov 2026

New enzyme discovery reveals how breast milk feeds infant gut bacteria

Microbiologists have found that an enzyme, not normally associated with microbial activities in the human gut, to have a role in how some bacteria access key nutrients in breast milk.

3 Nov 2026

RNA-protein interactions reveal new coronavirus drug targets

A study led by researchers at the University of California San Diego School of Medicine and University of California, Riverside (UCR) School of Medicine has identified new targets for antiviral drugs against coronaviruses, including SARS-CoV-2, the virus that causes COVID-19.

3 Nov 2026

A hidden structure may explain how infant gut bacteria gets nutrients

This study reveals how a β-sheet cradle in PNGaseABif enhances glycopeptide processing, offering insights into microbial nutrient access in the infant gut.

3 Nov 2026

Study uncovers translation control mechanisms driving tumor growth and therapy resistance

Decoding of messenger RNA (mRNA) occurs during translation, the vital cellular process that builds proteins. Errors in this process are known to lead to cancer growth.

3 Nov 2026

Plant-derived compound helps restore cancer cells' sensitivity to treatment

A natural plant compound may help overcome a built-in defense that allows many cancers to resist a class of drugs designed to restore normal gene activity, according to a study by researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center.

2 Nov 2026

Study identifies new targets for antiviral drugs against coronaviruses

2 Nov 2026

New strategy exploits a hidden genetic vulnerability in multiple cancers

Researchers have found a surprisingly common vulnerability in a broad variety of cancers and have begun designing drug compounds to exploit it, in a study led by investigators at Weill Cornell Medicine.

2 Nov 2026

New consensus offers guidance for management of neonatal lactose intolerance

Lactose is a major carbohydrate in human milk, but breaking it down requires lactase, an intestinal enzyme that can be insufficient in babies born prematurely.

2 Nov 2026

The type of fiber you eat shapes how gut bacteria feed and work together

A 2021 review examined how the chemical structure and physical properties of dietary fiber influence which gut bacteria can break it down and how microbial species compete and cooperate during fermentation. The authors described how these interactions contribute to short-chain fatty acid production, while emphasizing the need for further research involving intact plant foods to understand their implications for human health.

1 Nov 2026