Myelitis News and Research

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Review highlights challenges in managing childhood enterovirus infections

Enteroviruses (EVs) are a diverse group of viruses and a common cause of multiple infections in children.

1 Sep 2026

Immune surveillance in children sheds light on virus rebound after COVID

The first paper from a multi-year clinical research study has been published in The Lancet Infectious Diseases: Dynamics of Endemic Virus Re-emergence in Children in the USA Following the COVID-19 Pandemic (2022-2023): A Longitudinal Immunoepidemiologic Surveillance Study and demonstrates how the approach can improve modeling to better predict future outbreaks.

7 Aug 2025

Children show delayed exposure to respiratory viruses after COVID restrictions

COVID-19 prevention methods such as masking and social distancing also suppressed the circulation of common respiratory diseases, leaving young children lacking immunity to pathogens they otherwise would have been exposed to, a new multi-center clinical research study reveals.

6 Aug 2025

Gaps in surveillance leave European children at risk of acute flaccid myelitis

European researchers surveyed 28 countries and found acute flaccid myelitis (AFM) remains underreported, with only Norway maintaining dedicated surveillance. Most AFM cases coincided with years of high enterovirus D68 (EV-D68) circulation, highlighting gaps in monitoring and preparedness.

2 Jun 2025

Metagenomic sequencing improves detection of rare pathogens in CNS infections

New research shows that metagenomic next-generation sequencing (mNGS) over seven years increased pathogen detection in challenging CNS infections, identifying rare and unexpected microbes often missed by standard testing.

13 Nov 2024

New treatment offers hope for children with Acute Flaccid Myelitis

Researchers at Kennedy Krieger Institute's International Center for Spinal Cord Injury (ICSCI) have made a remarkable advancement in treating children with Acute Flaccid Myelitis (AFM), a rare but severe neurological condition that causes sudden paralysis.

12 Nov 2024

PCORI announces $165 million in new funding for comparative clinical effectiveness research

The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling more than $165 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in patient-centered CER.

13 Aug 2024

Rare but real: The neurological risks associated with vaccines

Review highlights the rare neurological risks associated with vaccination, emphasizing the importance of accurate detection and management strategies, particularly in the context of the COVID-19 pandemic.

9 Aug 2024

Clinical trial seeks to evaluate safety of new EV-D68 treatment

The National Institutes of Health (NIH) is sponsoring a clinical trial to evaluate the safety of an investigational monoclonal antibody to treat enterovirus D68 (EV-D68), which can cause severe respiratory and neurological diseases such as acute flaccid myelitis (AFM) – similar to polio. Scientists are striving to better understand AFM, which has emerged in the United States with spikes in cases every other year, primarily in the late-summer months over the last decade.

28 Jun 2024

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Government seeks views on proposed changes to the Health Protection Notification Regulations 2010

The Health Protection Notification Regulations 2010 (HPNR) help us respond promptly to suspected cases of infectious disease that could have an impact on public health.

13 Jul 2023

Prevalence study uncovers rising threat: enterovirus D68 and acute flaccid myelitis link

Study evaluated the changes in the transmission of EV-D68 in England inferred from seroprevalence data.

23 Jun 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

Study finds recent shingles infection increases the risk of myocardial infarction

Researchers assessed myocardial infarction (MI) risk after zoster infection.

30 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Researchers explore neurological manifestations among long COVID patients

In a new study, researchers assessed the long-term neurological sequelae in the post-acute phase of coronavirus disease 2019 (COVID-19) or long COVD.

26 Sep 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

CDC Health Alert Network provides recommendations to manage the recent increase in severe respiratory illness among children

The US CDC’s HAN has provided certain recommendations to inform healthcare providers, infection control professionals, clinical laboratories, and public health departments about the recent increase in pediatric cases of severe respiratory illness in several regions of the USA.

14 Sep 2022

Exploring a paralytic poliomyelitis case in an unvaccinated person

Researchers investigated the public health response to a paralytic poliomyelitis case in an unvaccinated person.

19 Aug 2022