Open Heart Surgery News and Research

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Brain connectivity differences found in infants with congenital heart disease

The prevalence of congenital heart disease points to the need for a better understanding of how it influences neurodevelopment. New in JNeurosci, Jung-Hoon Kim and Catherine Limperopoulos, from Children's National Hospital, led a study examining brain network disruptions that may be linked to congenital heart disease.

9 Mar 2026

Study supports safe same-day discharge following TAVI procedures

With careful selection, same-day hospital discharge was found to be feasible and safe in around one-fifth of patients undergoing transcatheter aortic valve implantation in a study presented today at the EAPCI Summit 2026.

19 Feb 2026

Major trial questions the need for invasive monitoring in heart surgery

Australians undergoing open-heart surgery could soon benefit from safer, simpler care and get home earlier thanks to the results of a world-first clinical trial led by Monash University's Victorian Heart Institute.

21 Jan 2026

New $8.5 million renewal grant fuels research on children's heart health

The National Institutes of Health has awarded the Icahn School of Medicine at Mount Sinai an $8.5 million renewal grant to continue groundbreaking work aimed at understanding and improving long-term outcomes for children with congenital heart disease-the most common type of birth defect in the United States.

7 Jan 2026

Researchers successfully perform coronary artery bypass without cutting the chest wall

In a world-first, a team of researchers at the National Institutes of Health (NIH) and Emory School of Medicine, Atlanta, has successfully performed a coronary artery bypass - a normally open-heart surgery - without cutting the chest wall.

6 Jan 2026

Mayo Clinic scientists create stem cell patch to heal hearts without surgery

Mayo Clinic researchers have developed a pioneering method to mend damaged hearts without open-heart surgery, an advance that could one day transform the treatment of heart failure.

5 Nov 2025

Flexible drug-delivery patch can promote tissue healing after a heart attack

MIT engineers have developed a flexible drug-delivery patch that can be placed on the heart after a heart attack to help promote healing and regeneration of cardiac tissue.

4 Nov 2025

HonorHealth study shows major breakthrough in treating structural shock

An 8-year HonorHealth Research Institute clinical trial, using non-surgical techniques, showed 86% of patients with a type of usually fatal low blood pressure known as 'structural shock' survived at least 3 months, while 73% survived at least 6 months, according to a study presented here at a major heart convention.

27 Jun 2025

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

Patients who underwent transcatheter aortic valve replacement (TAVR) with a valve designed to treat aortic regurgitation had an overall mortality rate of just 8.1% at one year, well below the trial's prespecified goal of 25% to show non-inferiority, according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

31 Mar 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

Heart failure patients benefit from dapagliflozin after TAVR procedure

Patients with heart failure who took dapagliflozin, a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, after undergoing transcatheter aortic valve replacement (TAVR) were significantly less likely to die or experience worsening heart failure at one year compared with patients who did not take the drug, according to a study presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

AI helps sonographers detect fetal abnormalities faster during 20-week pregnancy scan

Artificial intelligence (AI) could help sonographers identify any abnormalities at the 20-week pregnancy screening scan almost twice as quickly, without reducing the accuracy or reliability of diagnoses, a new study has shown.

27 Mar 2025

Singer Amy Grant highlights the need for support to fight women's heart disease

Singer-songwriter and musician, Amy Grant understands first-hand that cardiovascular disease (CVD) remains the No. 1 cause of death for women.

13 Nov 2024

Medical device may aid stroke survivors during heart valve replacement procedure

Recently published research shows a medical device may be beneficial for patients who have previously had a stroke and are planning to undergo a transcatheter aortic valve replacement, a type of heart valve operation.

31 Jul 2024

From Dr. Oz to heart valves: A tiny device charted a contentious path through the FDA

In 2013, the FDA approved an implantable device to treat leaky heart valves. Among its inventors was Mehmet Oz, the former television personality and former U.S. Senate candidate widely known as "Dr. Oz."

9 Jul 2024

NHS urged to expand TEER access for all mitral regurgitation patients

A life-saving medical procedure called Trans-catheter Edge-to-edge Repair (or TEER) for a common heart complaint is not available to many patients it could help.

20 May 2024

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

The adipose-neural axis plays an important role in arrhythmogenesis.

15 May 2024

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

A study in Cell Reports Medicine used an in vitro co-culture of adipocytes, cardiomyocytes, and sympathetic neurons to reveal that the adipose-neural axis plays a crucial role in arrhythmogenesis, driven by interactions between epicardial adipose tissue and the sympathetic nervous system.

14 May 2024

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.

14 May 2024

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

Administering tranexamic acid (TxA), a drug used to reduce bleeding during heart surgery, topically rather than intravenously did not meet its primary endpoint of reducing seizures and was stopped early due to an increased risk of bleeding events, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Open Heart Surgery News and Research

Brain connectivity differences found in infants with congenital heart disease

Study supports safe same-day discharge following TAVI procedures

Major trial questions the need for invasive monitoring in heart surgery

New $8.5 million renewal grant fuels research on children's heart health

Researchers successfully perform coronary artery bypass without cutting the chest wall

Mayo Clinic scientists create stem cell patch to heal hearts without surgery

Flexible drug-delivery patch can promote tissue healing after a heart attack

HonorHealth study shows major breakthrough in treating structural shock

Trilogy valve demonstrates safety and effectiveness in treating aortic regurgitation

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

Heart failure patients benefit from dapagliflozin after TAVR procedure

AI helps sonographers detect fetal abnormalities faster during 20-week pregnancy scan

Singer Amy Grant highlights the need for support to fight women's heart disease

Medical device may aid stroke survivors during heart valve replacement procedure

From Dr. Oz to heart valves: A tiny device charted a contentious path through the FDA

NHS urged to expand TEER access for all mitral regurgitation patients

New study reveals brain clearance of toxins is reduced during sleep and anesthesia

Interactions between adipose and sympathetic neurons contribute to cardiac arrhythmia

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

DEPOSITION trial evaluates the use of topical tranexamic acid during heart surgery

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