Primary Ciliary Dyskinesia News and Research

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Oral swab detects hidden inflammation in rare lung disease

Researchers at UTHealth Houston have identified different types of hidden systemic inflammation in patients with primary ciliary dyskinesia, even when they are not experiencing acute illness.

9 Jun 2026

Engineers create designer biobots using human lung cells

A brand-new engineering approach to generate "designer" biological robots using human lung cells is underway in Carnegie Mellon University's Ren lab.

26 Sep 2025

Researchers map atomic structure of protein complex driving cilia movement

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

28 Jul 2025

New guidelines aim to improve diagnosis and treatment of mycoplasma pneumoniae in children

The Chinese Medical Association has released new guidelines for diagnosing and treating Mycoplasma pneumoniae in children.

7 Apr 2025

Inogen receives FDA 510(k) clearance for SIMEOX 200 airway clearance device

Inogen, Inc., a medical technology company offering innovative respiratory products for use in the homecare setting, today announced that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the SIMEOX 200 Airway Clearance Device, expanding the company’s ability to market and meet the various needs of patients with chronic respiratory diseases in the U.S.

6 Jan 2025

Research reveals key role of mucin modification in muco-obstructive diseases

With each breath, a human may inhale thousands of harmful microbes into the lungs. Mucus, the gel-like moist substance coating the airways, is one of the first lines of defense and aids in removal these microbes.

24 Sep 2024

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Primary ciliary dyskenisia (PCD) is a rare genetic disease that causes the tiny hair-like filtration structures in the respiratory tract to stop working.

12 Sep 2023

UCL researchers produce first image of the structures that power human cilia

The first image of the structures that power human cilia – the tiny, hairlike projections that line our airways – has been produced by a team involving UCL researchers and could lead to much-needed treatments for people with rare cilial diseases.

13 Jun 2023

New method to improve diagnosis of Primary Ciliary Dyskinesia in preschool age children

University of Southampton researchers have recommended a method to help diagnose preschool age children with Primary Ciliary Dyskinesia (PCD).

27 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Scientists pinpoint the routes taken by SARS-CoV-2 to enter and exit cells in our nasal cavity

Somebody just coughed on you. On a plane. At a dinner party. In a supermarket line. If only there were a "morning after" nasal spray that could knock out respiratory viruses' ability to colonize your nose and throat.

5 Jan 2023

Cilia act as sensors to establish body left-right asymmetry during embryogenesis

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, liver, stomach, and brain.

5 Jan 2023

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Simple, minimally-invasive tool to study nasal airways of cystic fibrosis patients

A paper published today in Science Translational Medicine describes a simple, minimally invasive new tool for viewing differences in the nasal airways of cystic fibrosis patients in vivo at a cellular level.

8 Aug 2019

Study provides better understanding of how cilia work and what causes oscillations

Human bodies have some built-in systems to care for themselves. The cells that line our lungs, nose, brain and reproductive system have cilia, which are tiny, hair-like structures designed to sweep out fluids, cells and microbes to stay healthy.

30 Mar 2019

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

Babies exposed to higher levels of organochlorine compounds in womb may have worse lung function

Babies exposed to higher levels of organochlorine compounds in the womb go on to have worse lung function in childhood, according to new research presented today at the European Respiratory Society International Congress.

18 Sep 2018

Researchers uncover molecular roots of genetic lung disease

Respiratory infections peak during the winter months, and most people recover within a few weeks. But for those with a rare genetic lung disease, the sniffling, coughing and congestion never end.

24 Jan 2018

Defects in cerebrospinal fluid flow may contribute to scoliosis during adolescence

A new study in zebrafish suggests that irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence.

13 Jun 2016