Prolapse News and Research

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Prolapse literally means "To fall out of place". In medicine, prolapse is a condition where organs, such as the uterus, fall down or slip out of place. It is used for organs protruding through the vagina or the rectum, or for the misalignment of the valves of the heart.

New heart assembloid model mimics complex valve disorders

A multi-disciplinary, multi-institution group of researchers focused their expertise in genetics, mechanics, chemistry and biology on a chip the size of a postage stamp in order to model a particular class of heart conditions.

11 Aug 2026

New soft robotic heart accurately mimics the complex movements of human valves

Researchers at UNSW Sydney have developed a fully synthetic soft robotic heart that reproduces the complex movements and internal structures of the human heart, opening the door to better treatments, safer medical devices and more personalized care.

1 Jul 2026

Survey finds one in three women suffer silently with pelvic prolapse

Up to half of all women will experience some degree of pelvic organ prolapse in their lifetime. The condition can cause incontinence, constipation and the descent of the bladder or uterus into the vagina.

13 May 2026

Visceral fat strongly linked to urinary incontinence in women

The accumulation of fat in the abdominal region, especially visceral fat (fat that accumulates between organs), significantly increases the risk of stress urinary incontinence in women.

17 Apr 2026

Mount Sinai launches Adams Valve Institute for advanced heart care

The Mount Sinai Health System today announced the launch of the Adams Valve Institute, a new global center dedicated to advancing comprehensive care and surgical techniques for patients with heart valve disease.

7 Apr 2026

Many women suffer in silence from treatable pelvic floor conditions

Many women assume pelvic floor health issues are simply their fate—part of having vaginal deliveries, getting older, gaining weight or entering menopause. Perhaps they have watched their mothers and grandmothers live with symptoms, such as urinary incontinence and pain.

17 Dec 2025

Development of a polygenic risk score for pelvic organ prolapse in Chinese women

Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly impairs women's quality of life, yet genetic insights into non-European populations and comprehensive risk models that integrate genetic and clinical data remain insufficiently explored.

24 Nov 2025

Single-port robotic surgery transforms cancer care at NYU Langone Hospital—Long Island

After enduring seven prior abdominal surgeries, 64-year-old Joy Monetti from Islip was no stranger to painful procedures and lengthy recoveries.

17 Nov 2025

Mediterranean-style diets improve pelvic floor function and sexual health, review finds

This systematic review and meta-analysis of 31 studies reveals that healthy, anti-inflammatory dietary patterns, particularly the Mediterranean and DASH diets, are linked to improved sexual function and reduced incontinence symptoms in pelvic floor dysfunction. However, prospective evidence for incontinence improvement remains limited, suggesting that benefits may be mediated by metabolic and inflammatory pathways, especially in individuals with obesity or metabolic syndrome.

19 Oct 2025

Study links hysterectomy and bilateral oophorectomy to higher stroke risk

Given the seriousness and increased frequency of strokes, many studies have been conducted to assess the relationship between hysterectomy and/or bilateral oophorectomy and the risk of stroke with varying results.

3 Sep 2025

Regenerative strategy offers hope for women with pelvic organ prolapse

Pelvic organ prolapse (POP) is a disorder that primarily affects older women who have experienced multiple vaginal childbirths.

27 Aug 2025

Global experts release first guide to protect patients undergoing innovative surgery

Leading global doctors, researchers, and lawyers have joined forces with patient representatives and created the first-ever information guide to better support and protect patients across the world who are considering pioneering, but also potentially risky, surgery.

8 Jul 2025

Body composition associated with pelvic floor disorder symptoms in middle-aged women

According to a recent study conducted at the University of Jyväskylä, Finland, body composition is associated with symptoms of pelvic floor disorders in middle-aged women.

19 Jun 2025

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled "A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation."

13 Jun 2025

Heart valve abnormality raises long term risk of dangerous arrhythmias

People with a certain heart valve abnormality are at increased risk of severe heart rhythm disorders, even after successful valve surgery.

15 Apr 2025

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases

Scientists identified 195 genetic risk loci across 42 female reproductive health conditions, revealing shared genetic pathways and developing a polygenic risk score for intrahepatic cholestasis of pregnancy (ICP). These findings pave the way for personalized reproductive healthcare and targeted treatments based on genetic risk.

12 Mar 2025

Exploring sexual health challenges in women with pelvic floor disorders

Many women experience problems due to a weakened or damaged pelvic floor. These ailments are most common in pregnant women, women who have recently given birth, and menopausal women. However, pelvic floor disorders can affect all women.

10 Jan 2025

Senolytic agents show promise in mouse model of pelvic organ prolapse

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, "Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model."

22 Oct 2024

PCORI announces $165 million in new funding for comparative clinical effectiveness research

The Patient-Centered Outcomes Research Institute (PCORI) today announced the approval of funding awards totaling more than $165 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in patient-centered CER.

13 Aug 2024

Groundbreaking device revolutionizes pelvic floor training for physiotherapists

Pelvic floor problems like incontinence, prolapse, trouble going to the toilet and pain during sex are all too common, and often the best line of treatment is physio.

5 Aug 2024