Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Space station study tests colorectal cancer tumor avatars in microgravity

Researchers from Wake Forest Institute for Regenerative Medicine (WFIRM) are studying how microgravity affects how models of colorectal cancer cells respond to chemotherapy aboard the International Space Station.

9 Nov 2026

CIRM grant funds new stem cell therapy to heal hearts

A new $6.9 million grant from the California Institute for Regenerative Medicine (CIRM) will support preclinical development of an investigational cell therapy for the heart created by USC Stem Cell scientists.

5 Nov 2026

UCLA advances CRISPR gene-editing therapy for sickle cell disease

A UCLA-led team has described how they advanced an experimental CRISPR approach for sickle cell disease into a blood stem cell therapy that can be manufactured at the scale and quality required for a clinical trial.

4 Nov 2026

Deep learning method maps spatial architecture of brain cancer cells

Glioblastoma is the deadliest and most common type of malignant brain tumour in adults. One of the reasons it's almost always incurable is that individual tumour cells are very different from one another and shift dynamically between various 'states'.

4 Nov 2026

Spaceflight research opens new avenues for studying rare pediatric diseases

Earth-based hiPSC models have transformed disease research but remain limited by cellular immaturity, a strong reliance on glycolysis rather than oxidative phosphorylation (OXPHOS), and incomplete tissue architecture.

3 Nov 2026

Immune cell neighborhoods control cancer spread and metastasis formation

Published in Nature Cancer: Researchers at the Université libre de Bruxelles (ULB) have discovered that immune cells build distinct "neighborhoods" around cancer cells.

3 Nov 2026

Natural tooth protein could pave way for regenerative dental treatments

A protein that helps build teeth may one day be used to allow damaged teeth to repair themselves.

2 Nov 2026

Spatial study maps active epithelial crosstalk driving chronic periodontitis

Epithelial barriers are active organizers of tissue homeostasis, immune surveillance and host defense, yet chronic inflammation can corrupt their repair and communication with connective tissue.

2 Nov 2026

Mechanical force triggers metabolic changes that promote orthodontic bone formation

Bone adapts to mechanical force through coupled formation and resorption, a principle central to orthodontics.

30 Oct 2026

Researchers uncover molecular pathway controlling bone resorption and tooth eruption

RUNX2 is best known as a master transcription factor of osteoblast differentiation. Mutations in, or haploinsufficiency of RUNX2 cause CCD, a skeletal disorder characterized by delayed permanent tooth eruption, supernumerary teeth and clavicular defects.

30 Oct 2026

Study reveals immune rheostat maintaining skin barrier homeostasis

As the steadfast protector of the body's interior, the skin must be able to swiftly respond to stressors from the outside world and then return to a steady state in order to maintain everyday operations. Coordinating that agile response are epidermal stem cells, which produce the overlying protective layers of specialized skin cells sent to the surface while also maintaining a ready pool of new stem cells to draw from.

30 Oct 2026

Newly discovered protein helps preserve egg chromosome integrity during aging

Eggs follow a very different developmental path from sperm. Once a male hits puberty, sperm cells are produced continuously throughout his life.

29 Oct 2026

New mathematical method maps gene roles across different species

Much of what we know about biology comes from animal models, particularly mice. Applying these insights to humans, however, is not always straightforward.

29 Oct 2026

Ancient virus may help explain differences in human and chimpanzee brains

Pandemics can arise wherever animal or human populations are sufficiently large, and they are not confined to the modern age.

23 Oct 2026

Six-gene score could improve survival predictions for acute myeloid leukemia

The activity of six different genes can help determine patient survival of acute myeloid leukemia (AML), according to a study published today in Science Advances.

23 Oct 2026

Stem cell therapies may need new protein quality control standards

Current Good Manufacturing Practice (GMP) standards for cell therapies assess identity, viability, sterility, and genetic stability. For extracellular vesicle (EV) products, Minimal Information for Studies of Extracellular Vesicles (MISEV2023) guidance adds particle size, concentration, markers, morphology, contaminants, endotoxin, and assays.

22 Oct 2026