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Study shows how prostate tumors rewire metabolism to resist therapy

Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.

20 Aug 2026

More coffee, higher testosterone? This study found a more complicated picture

Higher habitual coffee intake was associated with a leaner body composition, lower circulating branched-chain amino acids, and distinct cardiometabolic patterns in 2,264 middle-aged Finnish adults. Hormonal associations differed by sex, with broader testosterone- and SHBG-related patterns in men and more limited SHBG-related changes in women.

20 Aug 2026

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

A review finds that restricting protein, particularly methionine, isoleucine, and valine, may improve metabolism and influence key aging pathways, largely in experimental models. Short human studies suggest metabolic benefits, but effects on lifespan remain unknown and restriction may harm people with unmet or increased protein needs.

3 Aug 2026

Consuming less protein could have greater health benefits and extend lifespan

Protein-fortified foods are popping up everywhere, from cereal and coffee to even protein water. But a new review covering over 350 papers on protein restriction and aging-publishing July 31 in the Cell Press journal Cell Press Blue-suggests that consuming less protein could have greater health benefits and could, in some cases, extend lifespan.

31 Jul 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

Retatrutide reshapes metabolism in obesity and type 2 diabetes, study finds

Retatrutide altered circulating metabolites and lipids linked to fatty acid oxidation and insulin resistance in people with obesity, with or without type 2 diabetes. These biomarker changes suggest improved metabolic health, but the post-hoc analysis remains hypothesis-generating and does not prove direct clinical benefit.

26 May 2026

AI model ranks genetic variants from severe to mild disease mutations

popEVE combines evolutionary insights with human population data to identify damaging genetic mutations, improving variant scoring for rare diseases.

3 Dec 2025

Molecular fingerprint predicts physical fitness in older adults

Could a simple blood test reveal how well someone is aging? A team of researchers led by Wolfram Weckwerth from the University of Vienna, Austria, and Nankai University, China, has combined advanced metabolomics with cutting-edge machine learning and a novel network modeling tool to uncover the key molecular processes underlying active aging.

30 Sep 2025

Flavonols found in foods can block drug resistance protein and boost medication absorption

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

6 Aug 2025

Subtle genetic shifts in brain enzyme offer clues to human evolution

The evolutionary success of our species may have hinged on minute changes to our brain biochemistry after we diverged from the lineage leading to Neanderthals and Denisovans about half a million years ago.

5 Aug 2025

Cricket flour pasta offers a safe, sustainable protein alternative

A 10% cricket flour blend in pasta enhances protein and minerals, offering a sustainable solution to malnutrition without compromising safety or flavor.

11 Jul 2025

Pasta gets a protein upgrade with eco-friendly cricket flour

Cricket flour is rich in protein, essential minerals, and healthy fats, offering a sustainable boost to the nutritional quality of wheat pasta. Adding just 10% cricket flour to pasta significantly improves nutrient content and meets daily amino acid requirements while ensuring food safety.

10 Jul 2025

How nutritious is dried Gapal? Study reveals its strengths and one hidden weakness

Researchers analyzed the nutritional composition of dried Gapal, a traditional fermented milk-cereal food from Burkina Faso, revealing its high carbohydrate and mineral content. Despite its nutritional potential, high phytic acid levels may limit mineral bioavailability, especially for zinc.

7 May 2025

Ultra-processed foods increase risk of anxiety and depression, study shows

A large UK Biobank study linked ultra-processed food (UPF) consumption to increased risks of anxiety, depression, substance use disorder, and other mental health outcomes. A metabolomic signature associated with UPF intake partially mediated these relationships, especially in adults under 60.

5 May 2025

Genetic mutation offers hope for better rheumatoid arthritis treatments

Research led by York University's Faculty of Health reveals how a specific mutation in a protein called TRAF1 can shut down an overactive immune response, dramatically reducing inflammation in mice.

27 Feb 2025

Human-specific gene variant may hold key to evolution of language

The origins of human language remain mysterious. Are we the only animals truly capable of complex speech? Are Homo sapiens the only hominids who could give detailed directions to a far-off freshwater source or describe the nuanced purples and reds of a dramatic sunset?

18 Feb 2025

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

Can a mushroom protein bar improve memory? Study suggests cognitive benefits of Termitomyces fuliginosus

The FCM protein snack bar, rich in amino acids and antioxidants, improves brain function and memory accuracy in just six weeks, according to recent research.

28 Oct 2024

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

Researchers utilie metabolomics to investigate the processes underlying dietary heme iron consumption and the risk of type 2 diabetes.

20 Aug 2024

Higher heme iron intake linked to increased risk of type 2 diabetes

Higher intake of heme iron, the type found in red meat and other animal products - as opposed to non-heme iron, found mostly in plant-based foods - was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led by researchers at Harvard T.H. Chan School of Public Health.

13 Aug 2024