Drug Discovery News and Research

RSS
The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
Utilizing AI to Accelerate the Field of High Content Analysis

Utilizing AI to Accelerate the Field of High Content Analysis

CDK6: a potential drug target for severe COVID-19

CDK6: a potential drug target for severe COVID-19

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Powerful tool to monitor membrane proteins trafficking for drug discovery

Powerful tool to monitor membrane proteins trafficking for drug discovery

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

The obstacles to developing high-throughput 3D wound healing models

The obstacles to developing high-throughput 3D wound healing models

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Study unveils several natural marine products as potential agents against SARS-CoV-2

Study unveils several natural marine products as potential agents against SARS-CoV-2

Optical coherence tomography reveals the beating and development of human heart organoids

Optical coherence tomography reveals the beating and development of human heart organoids

Acacetin shows potency against SARS-CoV-2 spike protein

Acacetin shows potency against SARS-CoV-2 spike protein

Mason scientists receive DOD funding for breast cancer prevention and treatment research

Mason scientists receive DOD funding for breast cancer prevention and treatment research

New smartphone app can calculate users’ genetic risk for coronary artery disease

New smartphone app can calculate users’ genetic risk for coronary artery disease

Canadian scientist discusses about how society could better prepare for future pandemics

Canadian scientist discusses about how society could better prepare for future pandemics

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

COVID-19 and the life sciences; what have we learned and where are we going?

COVID-19 and the life sciences; what have we learned and where are we going?

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

Novel drug candidate protects lab mice against cognitive decline by reducing brain inflammation

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Optibrium Adds Augmented Intelligence for Compound Design to its StarDrop Small Molecule Drug Discovery Software

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor