DNAPac PA100 Nucleic Acid HPLC Column from Thermo Scientific

The DNAPac® PA100 is a high-resolution anion-exchange column that provides single-base resolution. It is stable under denaturing conditions, rugged, reliable, and can be readily scaled up. The DNAPac PA100 is a 13 μm pellicular, nonporous polymeric resin with bound quaternary amine-functionalized MicroBeads™. The rapid mass-transport characteristics of this resin result in very high-resolution oligonucleotide separations.


  • Capable of n, n-1 resolution for oligonucleotides
  • Resolves oligonucleotides with secondary structures
  • Compatible with solvent, high pH, and high temperatures
  • Analyzes phosphorothioate-based clinical samples
  • Provides easy scale-up