Hypercarb HPLC Columns from Thermo Scientific

The Thermo Scientific Hypercarb HPLC Columns offer 100% porous graphitic carbon for extended separation capabilities. Enhanced retention of polar compounds and separation of structurally related analytes with stability at pH extremes and high temperature.


  • Exceptional retention of very polar analytes
  • True orthoganality to C18
  • Separated structurally related substances
  • Excellent for high-temperature applications.

Physical Properties of PGC (Hypercarb)

Property To meet requirement of
Particle shape: Spherical No micropores
Specific surface area: 120 m2/g Retention linearity and loading capacity
Median pore diameter: 250 Å Mass transfer for wide range of analyte shapes and sizes
Pore volume: 0.7 m3/g
Mean particle diameters: 3 µm, 5 µm Analytical HPLC columns
7 µm Preparative HPLC columns
30 µm SPE applications
Porosity: 75% Mass transfer within particles
% C: 100% Chemical stability
Mechanical strength: <400=""> Operational particle stability; pressure gradients in packing process