Biochemistry

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Metabolic engineering of cannabinoids – are we there yet?

There has recently been a surge in research into the biosynthetic pathways of cannabinoids and the potential for commercialized metabolic engineering.

19 Jun 2019

Researchers develop technique to track proteins on the surfaces of endoplasmic reticulum in cells

Researchers from Kanazawa University on the development of a technique to closely track a specific protein on the surfaces of endoplasmic reticulum (ER) in cells. Their findings are published in Bioorganic and Medicinal Chemistry.

17 Jun 2019

Researchers demystify the smell of dark chocolate

Chocolate is one of the most-consumed treats around the world, and the smell alone is usually enough to evoke strong cravings from even the most disciplined eaters.

17 Jun 2019

Scientists delay aging using protein found in young mice

Scientists have shown that a protein which is abundant in the blood of young mice can delay the aging process of older mice.

17 Jun 2019

Mutant bacterial receptor could help identify therapeutic compounds that inhibit quorum sensing

Researchers have developed a new mutant version of a receptor used by a bacterial pathogen for a chemical communication process called quorum sensing, according to a study published June 13 in the open-access journal PLOS Pathogens by Bonnie Bassler of Princeton University, and colleagues.

From PLOS ONE 14 Jun 2019

Research suggests new way to improve the efficacy of arthritis drug

Attaching a removable lock to an arthritis drug can make it safer and more effective, according to a new study publishing June 13 in the open-access journal PLOS Biology led by Wen-Wei Lin of Kaohsiung Medical University, Taiwan.

From PLOS ONE 14 Jun 2019

Ultra-Small Microelectrode Biosensors for Brain Injury Analysis

An interview with Stéphane Marinesco, discussing the development of ultra-small microelectrode biosensors for the analysis of traumatic brain injuries.

From Pittcon 14 Jun 2019

Super-Resolution Raman Imaging with Plasmonic Substrates

Renee Frontiera discusses the development of a super-resolution Raman microscope that could one day supersede fluorescence-based super-resolution microscopes.

From Pittcon 14 Jun 2019

Researchers challenge prior theories about how materials travel within E.coli cell

The flow of traffic through our nation's highways and byways is meticulously mapped and studied, but less is known about how materials in cells travel.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

Roche Diagnostics today announced the launch of the VENTANA ROS1 Antibody, the first and only in vitro diagnostic ROS1 immunohistochemistry assay. The test detects the presence of ROS1 protein in tissue, and may be useful in identifying ROS1-positive lung cancer cases.

From Roche Sequencing and Life Science 10 Jun 2019

Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.

7 Jun 2019

Scientists develop faster, easier method for making amino acid chains

Scientists often build new protein molecules by stringing groups of amino acids together. These amino acid chains, called polypeptides, are the building blocks needed in drug development and the creation of new biomaterials.

7 Jun 2019

Study provides new insight into how brain stem cells are activated

Our brains are notoriously bad at regenerating cells that have been lost through injury or disease. While therapies using neural stem cells (NSCs) hold the promise of replacing lost cells, scientists need to better understand how NSCs behave in the brain in order to develop effective treatments.

7 Jun 2019

A novel approach to intraplaque mast cell characterization in atherosclerosis

Researchers have devised a new flow-cytometric method to identify a subpopulation of intraplaque mast cells, the primary immune mediators of atherosclerosis.

6 Jun 2019

Researchers investigate how antibiotic produced by the microbiome kills bacteria

A research team from the Universities of Tübingen and Göttingen as well as from the German Center for Infection Research has investigated the mode of action of a new class of antibiotics that is highly effective against multidrug-resistant pathogens.

4 Jun 2019

Snapshot of chikungunya could help find new ways to prevent or treat viral arthritis

Chikungunya virus, once confined to the Eastern Hemisphere, has infected more than 1 million people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

4 Jun 2019

Researchers develop new method to reduce toxicity of gluten for people with celiac disease

A team of researchers from Universidad Politécnica de Madrid and Universidade de Trás-os-Montes e Alto Douro along with other research institutions have developed a method that will allow us to reduce the toxicity of gluten for people who suffer from celiac disease.

3 Jun 2019

Newly discovered mechanism of enzyme links circadian clock and fat metabolism

The enzyme Nocturnin, which governs daily tasks such as fat metabolism and energy usage, works in an entirely different way than previously thought, reported a team of researchers at Princeton University.

30 May 2019

Artificial intelligence set to revolutionize the field of proteomics

Using artificial intelligence, researchers at the Technical University of Munich have succeeded in making the mass analysis of proteins from any organism significantly faster than before and almost error-free.

29 May 2019