Biochemistry

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Research into structure of anticoagulant protein may open new avenues for treatment of thrombosis

A collaboration between researchers from Brazil and the United States may open new avenues for the treatment of thrombosis, the leading cause of death among cancer patients.

27 May 2019

University of Freiburg to receive 25.8 million euros for collaborative research centers

The Deutsche Forschungsgemeinschaft has approved grant applications for two collaborative research centers at the University of Freiburg: one for continued grant funding, and one for initial grant funding.

24 May 2019

Scientist studies people with Cockayne syndrome, who don’t get cancer

Hua-Ying Fan, PhD, studies the cells of people who don't get cancer. These people have an inherited disorder called Cockayne syndrome and, unfortunately, they don't live long enough to develop cancer. But by studying their cells, Fan may be able to help them and help people with cancer, too.

24 May 2019

Genetic switch that controls conversion of bad to good fat identified

Fat cells. They are the bane of a dieter's existence, but fat is important. Previous studies showed the subcutaneous white fat cells can transform to brown and beige varieties when exposed to cold stress.

23 May 2019

Researchers decode how molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide.

22 May 2019

Study provides new insights into key beneficial function of small ancient protein

Cell boundaries are made of lipids. When cells are severely damaged, these lipids need to be rapidly removed to avoid toxicity and facilitate tissue healing. Researchers have discovered that a small ancient protein, Serum Amyloid A (SAA), plays a previously unknown key role in this vital process.

21 May 2019

Cutting the test time for disease biomarkers using extracellular vesicles

When an individual has cancer, or any number of other diseases, early detection can make a huge difference in the outcome. A research team led by the University of Notre Dame is working to cut the test time for disease biomarkers.

21 May 2019

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Host-cell enzymes called PARP12 and PARP14 are important for inhibiting mutant forms of a coronavirus, according to a study published May 16 in the open-access journal PLOS Pathogens by Stanley Perlman of the University of Iowa, Anthony Fehr of the University of Kansas, and colleagues.

21 May 2019

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive protein modification that spurs on Alzheimer's disease.

18 May 2019

Marine natural compounds could be potential treatments for triple negative breast cancer

The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products.

17 May 2019

University of Virginia chemist identifies potential addiction-free pain reliever

An estimated 1.7 million Americans suffer from substance abuse disorders related to opioid use for pain relief, according to the National Institute on Drug Abuse.

17 May 2019

Neurological Side Effects of CAR T-Cell Therapy Revealed

Researchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect.

16 May 2019

New technique for separation of cancer cells enables comprehensive genetic profiling

A new technique for obtaining cancer cells from blood samples without contamination from blood cells has made it feasible to conduct detailed genetic analysis of cancer cells without the need for tumour biopsy.

16 May 2019

LC-MS/MS test for progesterone outperforms traditional immunoassays

Researchers have devised a cheap, non-invasive and specific means to monitor progesterone production in women.

15 May 2019

Microextraction gets an eco-friendly makeover in new cannabis study

Researchers have successfully demonstrated that IT-SPME coupled to nano-LC is an adequate analytical method for the characterization of cannabis traces.

15 May 2019

Probiotic-derived molecule optimizes the immune system to combat viral inflammatory diseases

The existence of certain microorganisms in your gut may bolster the immune system's ability to fend off a herpes viral attack that can cause fatal brain inflammation, reports a new City of Hope-led study.

14 May 2019

Brazilian researchers develop new strategy to starve triple negative breast cancer cells

A team of Brazilian researchers has developed a strategy that slows the growth of triple negative breast cancer cells by cutting them off from two major food sources.

13 May 2019

Scientists create building blocks that could be the basis for anti-cancer medicine

Kaunas Technology University, Lithuania scientists are working on a method to create building blocks which could be the basis for future anti-cancer medicine.

13 May 2019

Nanotubes enable movement of toxic protein linked to Huntington's disease

A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.

11 May 2019

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Most antibiotics work by interfering with critical functions such as DNA replication or construction of the bacterial cell wall.

10 May 2019

Biochemistry

Research into structure of anticoagulant protein may open new avenues for treatment of thrombosis

University of Freiburg to receive 25.8 million euros for collaborative research centers

Scientist studies people with Cockayne syndrome, who don’t get cancer

Genetic switch that controls conversion of bad to good fat identified

Researchers decode how molecular escorts help prevent cancer

Study provides new insights into key beneficial function of small ancient protein

Cutting the test time for disease biomarkers using extracellular vesicles

Host-cell enzymes vital for inhibiting mutant forms of coronavirus, study finds

Researchers map molecular structure and dynamics of one of Alzheimer's stickier culprits

Marine natural compounds could be potential treatments for triple negative breast cancer

University of Virginia chemist identifies potential addiction-free pain reliever

Neurological Side Effects of CAR T-Cell Therapy Revealed

New technique for separation of cancer cells enables comprehensive genetic profiling

LC-MS/MS test for progesterone outperforms traditional immunoassays

Microextraction gets an eco-friendly makeover in new cannabis study

Probiotic-derived molecule optimizes the immune system to combat viral inflammatory diseases

Brazilian researchers develop new strategy to starve triple negative breast cancer cells

Scientists create building blocks that could be the basis for anti-cancer medicine

Nanotubes enable movement of toxic protein linked to Huntington's disease

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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