Biochemistry

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Structure of bacteria responsible for traveler's diarrhea deciphered

For the first time researchers have deciphered the near-atomic structure of filaments, called 'pili', that extend from the surface of bacteria that cause traveler's diarrhea.

10 Jul 2019

Curved shape of bacteria can make it easier to find food

Research by scientists into why some bacteria have different shapes has found that a curved shape can make it easier to find food.

8 Jul 2019

Ludwig Cancer Research study discovers new cellular oxygen sensor

A Ludwig Cancer Research study led by Peter Ratcliffe and colleagues has discovered a previously overlooked oxygen sensor in animal cells that functions very much like one used by plants.

5 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin - NMR, EPR and Imaging 4 Jul 2019

HER2-positive breast cancer may be treated with imprinted nanospheres

A particularly aggressive, metastasizing form of cancer, HER2-positive breast cancer, may be treated with nanoscopic particles “imprinted” with specific binding sites for the receptor molecule HER2.

4 Jul 2019

Researchers reveal virulence regulatory mechanism in a superbug

As antibiotic resistance is growing and posing a threat on public health, developing new antibiotics has become more urgent than ever.

4 Jul 2019

Scientists discover new way to direct stem cells to heart tissue

In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK.

4 Jul 2019

Asynt's DrySyn OCTO Mini reaction helps optimize biocatalytic hydrogenation

The DrySyn OCTO Mini reaction station from Asynt is enabling researchers to optimise and expand the applications of HydRegen - an innovative, heterogeneous biocatalytic hydrogenation technology currently under development within the group of Prof. Kylie Vincent at the University of Oxford (UK).

From Asynt 3 Jul 2019

Unique method to study proteins could open new doors for medicinal research

Researchers at Chalmers University of Technology, Sweden, have developed a unique method for studying proteins which could open new doors for medicinal research.

3 Jul 2019

Carbohydrate plays important role in regulating blood pressure, research suggests

New research suggests that a particular type of carbohydrate plays an important role in regulating the blood pressure in the human body.

2 Jul 2019

Using popular anticonvulsant drug to thwart inflammation

Serious conditions, including sepsis, stem from inflammation in the body, and there is a lack of effective medication for sepsis.

2 Jul 2019

Study reveals time taken for DNA repair after chemotherapy

In the time it takes for an Amazon Prime delivery to arrive, cells damaged by chemotherapy can almost completely fix their most important DNA. That is the case in the livers of mice at least, according to a new study.

2 Jul 2019

Researchers determine atomic interactions that stabilize phase-changing proteins

Most of the well-studied proteins in our bodies are like metal; some can change shape easily, like aluminum foil, and others are rigid, like steel beams, but they typically have a solid, well-defined structure.

2 Jul 2019

Scientists unravel how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in unraveling the spent proteins.

29 Jun 2019

Artificial DNA can help release active ingredients from drugs in sequence

A drug with three active ingredients that are released in sequence at specific times: Thanks to the work of a team at the Technical University of Munich, what was once a pharmacologist's dream is now much closer to reality.

29 Jun 2019

Study solves mysteries of complex microRNA oncogenes

MicroRNAs are tiny molecules of nucleic acid that control gene expression, acting like a dimmer switch to tone down gene output at key positions in the network of information that governs a cell's function.

28 Jun 2019

Disrupting ChIP Assay Technology with New Advancements

The Chromatrap ChIP technology is a bead-free method of performing ChIP. The potential of the technology emerged from our capabilities in manufacturing porous plastic filters for the filtration and separation of biological materials.

From Chromatrap® - Porvair Sciences Ltd 27 Jun 2019

Compelling New Evidence Further Suggests Parkinson’s Disease Begins in the Gut

A new mouse study has revealed more evidence that Parkinson’s disease originates in the gut before traveling to the brain via the body’s neurons.

27 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Bruker announces novel phenomics solutions at Metabolomics 2019

At Metabolomics 2019, Bruker highlights innovative MS and NMR systems, and novel high-value solutions for molecular phenomics and clinical metabolomics.

From Bruker Life Sciences Mass Spectrometry 26 Jun 2019