Biochemistry

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New process could fast track antiviral and anticancer drug discovery

Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team.

7 Aug 2020

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

7 Aug 2020

A titanium oxide nanowire-based air filter can trap and destroy pathogens

Filter “paper” made from titanium oxide nanowires is capable of trapping pathogens and destroying them with light. This discovery by an EPFL laboratory could be put to use in personal protective equipment, as well as in ventilation and air conditioning systems.

7 Aug 2020

NSD2 enzyme protects against cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging.

7 Aug 2020

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

Despite frequent news announcing "medical breakthroughs," advancements in biomedical and clinical science typically happen incrementally.

7 Aug 2020

An 'intelligent' strategy for real-time evaluation of photothermal therapy efficiency on tumors

Photothermal therapy (PTT) is a promising alternative method for cancer treatment due to advantages of non-invasiveness, precise temporal and spatial control, strong specificity and high tumor destruction efficiency.

6 Aug 2020

Chemists discover a way to create synthetic version of natural anti-cancer compound

Scripps Research chemists Hans Renata, PhD, and Alexander Adibekian, PhD, have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as an anti-cancer agent.

6 Aug 2020

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

6 Aug 2020

Study shows how microbes influence the quality of sausage and other fermented foods

Microbes in "starter cultures" impart a distinctive tang and longer shelf life to food like sourdough bread, yogurt and kimchi through the process of fermentation.

6 Aug 2020

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center.

6 Aug 2020

SARS-CoV-2 may not be targeting taste bud cells

An intriguing early symptom among some COVID-19 patients is the loss of the sense of smell and/or taste, which has led to the suspicion that the virus that causes the illness, SARS-CoV-2, could be targeting taste buds.

5 Aug 2020

Study provides comprehensive update on ACE2 enzyme with key role in SARS-CoV-2 infection

Researchers at Uppsala University have described the presence, throughout the human body, of the enzyme ACE2.

5 Aug 2020

Biomedical engineers create artificial organelles to control biological function in cells

Biomedical engineers at Duke University have demonstrated a method for controlling the phase separation of an emerging class of proteins to create artificial membrane-less organelles within human cells.

4 Aug 2020

UC Riverside joins ATP-Bio to preserve a wide range of biological systems

The National Science Foundation, or NSF, announced today that it has awarded a $26 million Engineering Research Center grant to the University of Minnesota and Massachusetts General Hospital, in collaboration with UC Riverside and UC Berkeley.

4 Aug 2020

Decoy receptor neutralizes SARS-CoV-2 virus in tissue cultures

As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they're exposed. A new study suggests luring the virus with a decoy - an engineered, free-floating receptor protein - binds the virus and blocks infection.

4 Aug 2020

Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Researchers develop a redox potential-controlled, cost-effective chemical production method

A team of researchers from Japan has demonstrated a light-based reaction that yields high numbers of the base chemical component required to produce bioactive compounds used in common industry products.

3 Aug 2020

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron.

3 Aug 2020

Konstanz biologists receive Ursula M. Händel Animal Welfare Prize

Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the German Research Foundation.

31 Jul 2020

Research may provide new insights into wound healing

When we get a wound on our skin, the cells in our bodies quickly mobilize to repair it. While it has been known how cells heal wounds and how scars form, a team led by researchers from Washington University in St. Louis has determined for the first time how the process begins, which may provide new insight into wound healing, fibrosis and cancer metastasis.

29 Jul 2020

Biochemistry

New process could fast track antiviral and anticancer drug discovery

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

A titanium oxide nanowire-based air filter can trap and destroy pathogens

NSD2 enzyme protects against cellular senescence

USF Health researchers develop new reporter mouse strain for identifying P2X2-expressing cells

An 'intelligent' strategy for real-time evaluation of photothermal therapy efficiency on tumors

Chemists discover a way to create synthetic version of natural anti-cancer compound

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Study shows how microbes influence the quality of sausage and other fermented foods

HDAC6 inhibitors increase efficacy of immunotherapy in triple-negative breast cancer

SARS-CoV-2 may not be targeting taste bud cells

Study provides comprehensive update on ACE2 enzyme with key role in SARS-CoV-2 infection

Biomedical engineers create artificial organelles to control biological function in cells

UC Riverside joins ATP-Bio to preserve a wide range of biological systems

Decoy receptor neutralizes SARS-CoV-2 virus in tissue cultures

Researchers develop scalable strategy to find novel molecular glue degraders

Researchers develop a redox potential-controlled, cost-effective chemical production method

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

Konstanz biologists receive Ursula M. Händel Animal Welfare Prize

Research may provide new insights into wound healing

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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