Biochemistry

RSS

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level.

21 Jul 2020

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.

21 Jul 2020

Brains of all mammals exhibit equal connectivity, study finds

Researchers at Tel Aviv University, led by Prof. Yaniv Assaf of the School of Neurobiology, Biochemistry and Biophysics and the Sagol School of Neuroscience and Prof. Yossi Yovel of the School of Zoology, the Sagol School of Neuroscience, and the Steinhardt Museum of Natural History, conducted a first-of-its-kind study designed to investigate brain connectivity in 130 mammalian species.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Study shows a promising, new approach to treating Alzheimer's disease

With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

17 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Emerging hydrogel material could improve oral drug delivery

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

16 Jul 2020

Durable coating for hard surfaces could help avoid food contamination

In the future, a durable coating could help keep food-contact surfaces clean in the food processing industry, including in meat processing plants.

16 Jul 2020

Scientists explore how scorpion toxin may help treat heart attacks

Scientists are discovering potential life-saving medicines from an unlikely source: the venom of creatures like snakes, spiders and scorpions.

15 Jul 2020

UMass Amherst chemist and kinesiologist synthesize artificial fuel for muscle

A chemist and kinesiologist got on a bus, but this isn't the set-up to a joke. Instead, kinesiologist and lead author Ned Debold and chemist Dhandapani Venkataraman, "DV," began talking on their bus commute to the University of Massachusetts Amherst and discovered their mutual interest in how energy is converted from one form to another - for Debold, in muscle tissue and for DV, in solar cells.

14 Jul 2020

Compound in pickled capers can directly regulate proteins required for bodily processes

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

14 Jul 2020

New method can enhance the effectiveness of bacteria used in biotechnological applications

Scientists have developed a new computational technique that can be used to enhance the effectiveness of bacteria used in biotechnological applications.

13 Jul 2020

Fully automated chip can reliably determine blood type within minutes

The need to first zero in on a blood group can delay blood transfusions in emergency situations, and this in turn can prove fatal.

13 Jul 2020

Novel drug could enable the immune system to attack ovarian cancer

A drug known as SP-2577 could help enable the body's own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

13 Jul 2020

Research identifies specific brain cells that trigger sugar consumption and cravings

New research has identified the specific brain cells that control how much sugar you eat and how much you crave sweet tasting food.

12 Jul 2020

Newly discovered chemical compound shows potential to become treatment for brain disorders

Researchers at IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) discovered a novel chemical compound, which has the potential to became a new drug for the treatment of core symptoms of brain disorders like Down syndrome and autism.

11 Jul 2020

UQ researchers reveal three-dimensional structure of important enzyme

Advanced herbicides and treatments for infection may result from the unravelling of a 50-year-old mystery by University of Queensland researchers.

11 Jul 2020

Scientists identify a new role for covalent linker in transmembrane ion channels

In the molecular-level world of ion channels - passageways through membranes that carry signals in a cell's environment and allow it to respond - researchers have debated about the role of a small piece of the channel called a linker, says computational biophysicist Jianhan Chen at the University of Massachusetts Amherst.

10 Jul 2020

UC Santa Cruz- led research center focuses on botanical natural products

Although millions of people take plant-based dietary supplements or herbal medicines, understanding the effects of these natural products on human health has proven to be extremely challenging.

8 Jul 2020

Biochemistry

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

Brains of all mammals exhibit equal connectivity, study finds

How immune cells switch to attack mode

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Study shows a promising, new approach to treating Alzheimer's disease

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Emerging hydrogel material could improve oral drug delivery

Durable coating for hard surfaces could help avoid food contamination

Scientists explore how scorpion toxin may help treat heart attacks

UMass Amherst chemist and kinesiologist synthesize artificial fuel for muscle

Compound in pickled capers can directly regulate proteins required for bodily processes

New method can enhance the effectiveness of bacteria used in biotechnological applications

Fully automated chip can reliably determine blood type within minutes

Novel drug could enable the immune system to attack ovarian cancer

Research identifies specific brain cells that trigger sugar consumption and cravings

Newly discovered chemical compound shows potential to become treatment for brain disorders

UQ researchers reveal three-dimensional structure of important enzyme

Scientists identify a new role for covalent linker in transmembrane ion channels

UC Santa Cruz- led research center focuses on botanical natural products

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News