Biochemistry

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Researchers develop scalable strategy to find novel molecular glue degraders

Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development.

4 Aug 2020

Researchers develop a redox potential-controlled, cost-effective chemical production method

A team of researchers from Japan has demonstrated a light-based reaction that yields high numbers of the base chemical component required to produce bioactive compounds used in common industry products.

3 Aug 2020

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron.

3 Aug 2020

Konstanz biologists receive Ursula M. Händel Animal Welfare Prize

Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the German Research Foundation.

31 Jul 2020

Research may provide new insights into wound healing

When we get a wound on our skin, the cells in our bodies quickly mobilize to repair it. While it has been known how cells heal wounds and how scars form, a team led by researchers from Washington University in St. Louis has determined for the first time how the process begins, which may provide new insight into wound healing, fibrosis and cancer metastasis.

29 Jul 2020

Investigational drug for Alzheimer's disease may help autistic children

An extensive international study led by Prof. Illana Gozes of Tel Aviv University's Department of Human Molecular Genetics and Biochemistry found deposits of the tau protein typically found in Alzheimer's patients in tissues taken from the postmortem brain of a 7-year-old autistic child.

28 Jul 2020

Low-cost, environmentally-friendly hand sanitizer produced from plant and paper waste

A Tel Aviv University breakthrough allows, for the first time, a local production of ethanol -- and hand sanitizer -- based on plant and paper waste, using a novel lignin (a substance found in plants) degradation process.

27 Jul 2020

Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt crystals do occur even at low salt concentrations in nanoscales, and that it can accelerate the aggregation of the neurotoxic amyloid-β peptides implicated in its pathogenesis.

27 Jul 2020

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest® bio-ADM®, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin. Blood levels of bio-ADM® reflect in real-time the functional status of the endothelium, the inner cell sheet of blood vessels.

24 Jul 2020

Century-old mercury pollution is persistent in Connecticut's Still River

Western Connecticut is known for rolling hills, rich history, and industry, such as hat making. Once called the "Hat City of the World," Danbury thrived.

23 Jul 2020

Gene in fat cells plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

23 Jul 2020

Disinfection of drinking water using UV light

While awaiting full access to their labs due to COVID-19 restrictions, scientists at the National Institute of Standards and Technology have taken this rare opportunity to report the technical details of pioneering research they conducted on the disinfection of drinking water using ultraviolet light.

23 Jul 2020

New biomolecules can benefit agricultural and pharmaceutical sectors

These molecules of plant origin may be of use to the agricultural and pharmaceutical sectors. Researchers from the Biochemistry and Biotechnology Research Group at the Universitat Jaume Ihave identified and obtained biomolecules of plant origin, which have been tested against plant pathogens and pathogens of clinical interest, with the aim of obtaining high-quality commercial products that can be applied in the agricultural and pharmaceutical sectors.

23 Jul 2020

New project explores how algae could be key to next generation of sunscreens

A Swansea University project exploring how to use algae to create the next generation of sunscreens has now teamed up with an award-winning skincare firm to help develop the idea.

22 Jul 2020

Antioxidant-rich blueberry, persimmon waste powders may have beneficial effects on gut microbiota

Feeding the world's growing population in a sustainable way is no easy task. That's why scientists are exploring options for transforming fruit and vegetable byproducts -- such as peels or pulp discarded during processing -- into nutritious food ingredients and supplements.

22 Jul 2020