Biochemistry

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Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Determining microsatellite instability status using multiplex PCR-based methods used to screen for Lynch Syndrome, a dominant hereditary cancer propensity.

From Promega Corporation 24 Jan 2020

New discovery changes the understanding of gene expression

A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality.

22 Jan 2020

High-speed, precise liquid and gas handling products at SLAS 2020

Festo debuts a new generation of high speed, flexible, and precise liquid dispensing and gas handling products at SLAS, January 27-29, in San Diego.

22 Jan 2020

New method determines the atomic structure of natural products more rapidly, accurately

Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry.

21 Jan 2020

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

Enterprise Therapeutics Ltd, a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of patients suffering with respiratory disease, today announced the publication of its first peer-reviewed paper.

21 Jan 2020

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

PhoreMost will deploy its in-house expertise and next-generation phenotypic screening platform, SITESEEKER, in disease-relevant pathways nominated by Otsuka.

From PhoreMost 21 Jan 2020

Certain enzymes implicated in diseases like cancer also destroy each other

Like motley bandits, certain enzymes implicated in cancer and other diseases also annihilate each other. A new study reveals details of their mutual foils in the hopes that these behaviors can be leveraged to fight the enzymes' disease potential.

20 Jan 2020

Researchers develop self-assembled artificial microtubule like LEGO building blocks

Simple LEGO bricks can be assembled to more complicated structures, which can be further associated into a wide variety of complex architectures, from automobiles, rockets, and ships to gigantic castles and amusement parks.

17 Jan 2020

Editor's Pick: Life Science Interviews from 2019

In this article, our editors look back at their favorite life science interviews from 2019.

17 Jan 2020

Research could be starting point for wound dressings with 'built-in infection stoppers'

Infections are a dreaded threat that can have fatal consequences after an operation, in the treatment of wounds, and during tissue engineering.

17 Jan 2020

'Pulling the plug' on calcium pumps to kill pancreatic cancer cells

UK scientists have identified a new way to kill pancreatic cancer cells by 'pulling the plug' on the energy generator that fuels calcium pumps on their cell surface.

16 Jan 2020

Molecular-level understanding of drug interactions could pave way for better malaria treatments

The process of crystallization is central to drug development, petrochemical processing and other industrial actions, but scientists say they still are learning about the complex interactions involved in the building and dissolution of crystals.

16 Jan 2020

New method for detection of microcystins and nodularin in human urine

Blooms of toxin-producing algae exploded in both fresh and salt water ecosystems in southern Florida during the summer months of 2018, impacting wildlife and humans living in these marine environments.

16 Jan 2020

MDI Biological Laboratory will use African turquoise killifish model to study aging

The study of therapies and interventions to expand healthy human lifespan has been limited by a lack of animal models: traditional vertebrate models such as the mouse live too long to get rapid results, while the most popular model, a roundworm called C.elegans that lives for only three weeks, is rungs away from humans on the evolutionary ladder.

16 Jan 2020

BPA activates immune response in mice that persists for at least three generations

Some plastic food and beverage containers still contain bisphenol A, which can mimic the hormone estrogen. Although experts say that small amounts of BPA detected in foods are unlikely to cause problems, some people worry that constant low-level exposures could have health effects, especially for developing fetuses, infants and children.

16 Jan 2020

New tool could speed up neuroscience research into pheromones

Researchers at Worcester Polytechnic Institute have developed a tool to identify molecular receptors in worms that are involved in sensing pheromones related to mating, an advance that could speed up neuroscience research into pheromones by eliminating months of work.

14 Jan 2020

Bath scientists identify promising route to develop new treatments for skin cancer

A promising route to develop new treatments for skin cancer has been identified by University of Bath scientists, who have found a molecule that suppresses melanoma tumor growth.

14 Jan 2020

Study uncovers how rice blast fungus uses its own cell wall to launch an attack

In response to environmental changes and nutrient starvation, cells are known to undergo extreme alterations. This includes switching from one type to another (“differentiation”) and changes in metabolic pathways (“metabolic switching”).

14 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Life Sciences Mass Spectrometry 14 Jan 2020

A controlled phage therapy to target drug-resistant pathogens

The fight against drug-resistant pathogens remains an intense one. While the Centers for Disease Control's 2019 "biggest threats" report reveals an overall decrease in drug-resistant microbe-related deaths as compared to its previous report (2013) the agency also cautions that new forms of drug-resistant pathogens are still emerging.

13 Jan 2020

Biochemistry

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

New discovery changes the understanding of gene expression

High-speed, precise liquid and gas handling products at SLAS 2020

New method determines the atomic structure of natural products more rapidly, accurately

Enterprise Therapeutics publishes open access paper on novel approach to treat cystic fibrosis

SITESEEKER to be used for Otsuka’s therapeutics discovery programs

Certain enzymes implicated in diseases like cancer also destroy each other

Researchers develop self-assembled artificial microtubule like LEGO building blocks

Editor's Pick: Life Science Interviews from 2019

Research could be starting point for wound dressings with 'built-in infection stoppers'

'Pulling the plug' on calcium pumps to kill pancreatic cancer cells

Molecular-level understanding of drug interactions could pave way for better malaria treatments

New method for detection of microcystins and nodularin in human urine

MDI Biological Laboratory will use African turquoise killifish model to study aging

BPA activates immune response in mice that persists for at least three generations

New tool could speed up neuroscience research into pheromones

Bath scientists identify promising route to develop new treatments for skin cancer

Study uncovers how rice blast fungus uses its own cell wall to launch an attack

How SpatialOMx is Delivering New Insights into Disease Research

A controlled phage therapy to target drug-resistant pathogens

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News