Cell Biology

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Low dose of a four-drug combination helps prevent cancer metastasis in mice

Low doses of a four-drug combination helps prevent the spread of cancer in mice without triggering drug resistance or recurrence, shows a study published today in eLife.

11 May 2021

Cerebral organoids provide new insight into role of key enzyme in natural brain development

Like many around the world, the lab of Professor Mriganka Sur in The Picower Institute for Learning and Memory at MIT has embraced the young technology of cerebral organoids, or "minibrains," for studying human brain development in health and disease.

11 May 2021

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

A new approach to tackling viruses by targeting the 'control center' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defense against future pandemics, according to new research at the University of Birmingham.

11 May 2021

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires' disease to set up house in the cells of humans and other hosts.

10 May 2021

Machine learning technique detects epigenetic drivers of cancers

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

10 May 2021

New findings challenge the decades-old working mechanism of the hearing organ

Researchers at Linköping University, Sweden, have made several discoveries on the functioning mechanisms of the inner hair cells of the ear, which convert sounds into nerve signals that are processed in the brain.

10 May 2021

Rice University neurobiologist wins NIH grant to study enteric nervous system development

Rice University neurobiologist Rosa Uribe will be hitting the books for her latest study of the digestive system, but some of the pages in her books are a billion years old.

10 May 2021

Researchers study how cancer cells re-organize 3D structure of DNA to ramp up oncogene activity

In cancer, a lot of biology goes awry: Genes mutate, molecular processes change dramatically, and cells proliferate uncontrollably to form entirely new tissues that we call tumors.

10 May 2021

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified.

10 May 2021

Microneedle patch delivers antibiotics to effectively reduce MRSA bacteria in the skin

MRSA skin infections are often treated with intravenous injection of antibiotics, which can cause significant side effects and promote the development of resistant bacterial strains.

10 May 2021

Researchers improve method to inhibit viruses that cause childhood respiratory infections

By engineering a short chunk of protein, or peptide, that can prevent the attachment of human parainfluenza viruses to cells, researchers have improved a method in rodent models intended to help keep children healthy.

10 May 2021

New research lays the groundwork for an effective salmonella vaccine

With the COVID-19 vaccines on many people's minds, some may be surprised to learn that we do not yet have vaccines for many common infectious diseases.

7 May 2021

Absence of key gene causes severe hearing loss

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

7 May 2021

Brain-targeting drug delivery with nano-scaled apoptotic bodies

Scientists from Nanjing University and University of Macau have discovered nano-scaled apoptotic bodies (ABs) as a new brain-targeting drug carrier, bringing new promise for the Parkinson's Disease as well as other brain diseases.

7 May 2021

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means 'eating cells.' The housekeepers engulf and ingest the dying cells and break them down to effectively eliminate them.

7 May 2021

Researchers describe the key facet of sexual determination in mammalian models

Early in human development, during the first trimester of gestation, a fetus may have XX or XY chromosomes that indicate its sex. Yet at this stage a mass of cells known as the bipotential gonad that ultimately develops into either ovaries or testes has yet to commit to its final destiny.

7 May 2021

Cell Biology

Low dose of a four-drug combination helps prevent cancer metastasis in mice

Cerebral organoids provide new insight into role of key enzyme in natural brain development

New approach targeting viral RNA could lead to broad spectrum anti-viral drugs

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Machine learning technique detects epigenetic drivers of cancers

New findings challenge the decades-old working mechanism of the hearing organ

Rice University neurobiologist wins NIH grant to study enteric nervous system development

Researchers study how cancer cells re-organize 3D structure of DNA to ramp up oncogene activity

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

Microneedle patch delivers antibiotics to effectively reduce MRSA bacteria in the skin

Researchers improve method to inhibit viruses that cause childhood respiratory infections

New research lays the groundwork for an effective salmonella vaccine

Absence of key gene causes severe hearing loss

Brain-targeting drug delivery with nano-scaled apoptotic bodies

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Researchers describe the key facet of sexual determination in mammalian models

A single archaeal enzyme can produce a spectacular range of natural and non-natural cardiolipins

UMass Amherst researchers achieve breakthrough in the fight against cancer

Study provides a better understanding of the complex interplay of ncRNAs with gene regulation

Scientists discover fundamental regulation mechanism of proteins

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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